Ligand: F8H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6GQMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 6GQMA P10721 569 931 976.0 F8H:61001 Type2 Inactive DFGout 16.2292 10.3879 BBAminus -136.57, -179.47 -147.93, 100.03 -59.52, -34.87 275.16, 81.94 48.12, -112.93 in-in in 7.5565 Saltbr-in 2.7555 HRD-in -68.29, -51.8 77.27, -17.33 in-out-in SNCioi out-in ActLoopNT-out 16.474 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.29, 100.87 APE9-dihe-in -115.89, 146.45 APE8-dihe-in -80.79, 61.87 APE8-rot-na 34.09 APE67-dihe-in -66.61, -10.92 -45.17, -44.75 APE12-dist-na 16.6024 APE11-dist-na 13.1429 APE10-dist-na 11.0048 APE9-dist-in 7.8815 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.0 0.205 0.23 A 328.0 296.0 6 30 30 0 [[589, 926]] 1.0 6gqm TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMB P10721 577 931 976.0 F8H:61001 Type2 Inactive DFGout 16.2081 10.3979 BBAminus -135.72, -179.99 -147.49, 100.7 -59.32, -34.43 274.81, 80.92 50.64, -114.3 in-in in 7.5501 Saltbr-in 2.7586 HRD-in -67.84, -52.64 77.31, -15.84 in-out-in SNCioi out-in ActLoopNT-out 16.4179 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.68, 94.89 APE9-dihe-in -113.11, 150.6 APE8-dihe-in -84.09, 61.58 APE8-rot-na 33.61 APE67-dihe-in -66.61, -10.94 -43.73, -45.44 APE12-dist-na 16.9463 APE11-dist-na 13.5349 APE10-dist-na 11.221 APE9-dist-in 7.9334 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.0 0.205 0.23 B 328.0 288.0 6 30 30 0 [[589, 926]] 1.0 6gqm TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: F8H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6GQMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 6GQMA P10721 569 931 976.0 F8H:61001 Type2 Inactive DFGout 16.2292 10.3879 BBAminus -136.57, -179.47 -147.93, 100.03 -59.52, -34.87 275.16, 81.94 48.12, -112.93 in-in in 7.5565 Saltbr-in 2.7555 HRD-in -68.29, -51.8 77.27, -17.33 in-out-in SNCioi out-in ActLoopNT-out 16.474 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.29, 100.87 APE9-dihe-in -115.89, 146.45 APE8-dihe-in -80.79, 61.87 APE8-rot-na 34.09 APE67-dihe-in -66.61, -10.92 -45.17, -44.75 APE12-dist-na 16.6024 APE11-dist-na 13.1429 APE10-dist-na 11.0048 APE9-dist-in 7.8815 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.0 0.205 0.23 A 328.0 296.0 6 30 30 0 [[589, 926]] 1.0 6gqm Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMB P10721 577 931 976.0 F8H:61001 Type2 Inactive DFGout 16.2081 10.3979 BBAminus -135.72, -179.99 -147.49, 100.7 -59.32, -34.43 274.81, 80.92 50.64, -114.3 in-in in 7.5501 Saltbr-in 2.7586 HRD-in -67.84, -52.64 77.31, -15.84 in-out-in SNCioi out-in ActLoopNT-out 16.4179 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.68, 94.89 APE9-dihe-in -113.11, 150.6 APE8-dihe-in -84.09, 61.58 APE8-rot-na 33.61 APE67-dihe-in -66.61, -10.94 -43.73, -45.44 APE12-dist-na 16.9463 APE11-dist-na 13.5349 APE10-dist-na 11.221 APE9-dist-in 7.9334 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.0 0.205 0.23 B 328.0 288.0 6 30 30 0 [[589, 926]] 1.0 6gqm Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: F8H

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name