Ligand: F8B

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6GQQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KDR VGFR2_HUMAN 6GQQA P35968 813 1167 1356.0 F8B:61201 Type2 Inactive DFGout 16.3179 9.8934 BBAminus -140.35, 179.68 -146.82, 105.0 -62.58, -33.91 278.73, 81.84 52.08, -122.03 in-in in 7.8551 Saltbr-in 2.8701 HRD-in -79.41, -58.06 81.99, -7.96 in-out-out SNCioo out-out ActLoopNT-out 16.6419 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -102.87, 113.66 APE9-dihe-in -116.65, 151.24 APE8-dihe-in -82.45, 66.44 APE8-rot-na 31.58 APE67-dihe-in -64.76, -12.48 -47.19, -45.1 APE12-dist-na 16.8675 APE11-dist-na 13.2075 APE10-dist-na 11.6327 APE9-dist-out 8.0466 None None None XRAY 1.52 0.178 0.204 A 322.0 304.0 0 30 30 0 [[834, 1162]] 1.0 6gqq TYR_KDR_HUMAN TYR 4.4e-100 340.2 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 6GQLA P10721 568 931 976.0 F8B:61001 Type2 Inactive DFGout 16.2978 10.4066 BBAminus -139.81, -179.58 -147.15, 104.1 -62.76, -35.23 278.0, 81.24 49.83, -115.81 in-in in 7.688 Saltbr-in 2.7024 HRD-in -69.78, -53.4 80.29, -13.23 in-out-in SNCioi out-in ActLoopNT-out 16.6043 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -122.57, 101.18 APE9-dihe-in -117.98, 151.43 APE8-dihe-in -83.84, 67.65 APE8-rot-na 33.5 APE67-dihe-in -63.86, -15.23 -50.06, -43.24 APE12-dist-na 16.889 APE11-dist-na 13.6286 APE10-dist-na 11.4181 APE9-dist-in 7.998 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.01 0.202 0.222 A 328.0 297.0 6 30 30 0 [[589, 926]] 1.0 6gql TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLB P10721 577 931 976.0 F8B:61001 Type2 Inactive DFGout 16.337 10.4783 BBAminus -138.32, -179.86 -148.07, 104.2 -62.14, -34.67 277.43, 81.68 50.68, -116.78 in-in in 7.7307 Saltbr-in 2.7414 HRD-in -68.79, -54.39 79.8, -13.05 in-out-out SNCioo out-out ActLoopNT-out 16.5368 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -117.3, 101.37 APE9-dihe-in -120.57, 151.18 APE8-dihe-in -84.13, 66.79 APE8-rot-na 32.76 APE67-dihe-in -64.17, -15.21 -49.48, -43.05 APE12-dist-na 17.1643 APE11-dist-na 13.913 APE10-dist-na 11.5187 APE9-dist-out 8.0601 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.01 0.202 0.222 B 328.0 286.0 8 30 30 0 [[589, 926]] 1.0 6gql TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: F8B

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6GQQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KDR VGFR2_HUMAN 6GQQA P35968 813 1167 1356.0 F8B:61201 Type2 Inactive DFGout 16.3179 9.8934 BBAminus -140.35, 179.68 -146.82, 105.0 -62.58, -33.91 278.73, 81.84 52.08, -122.03 in-in in 7.8551 Saltbr-in 2.8701 HRD-in -79.41, -58.06 81.99, -7.96 in-out-out SNCioo out-out ActLoopNT-out 16.6419 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -102.87, 113.66 APE9-dihe-in -116.65, 151.24 APE8-dihe-in -82.45, 66.44 APE8-rot-na 31.58 APE67-dihe-in -64.76, -12.48 -47.19, -45.1 APE12-dist-na 16.8675 APE11-dist-na 13.2075 APE10-dist-na 11.6327 APE9-dist-out 8.0466 None None None XRAY 1.52 0.178 0.204 A 322.0 304.0 0 30 30 0 [[834, 1162]] 1.0 6gqq Homo sapiens TYR_KDR_HUMAN TYR 4.4e-100 340.2 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 6GQLA P10721 568 931 976.0 F8B:61001 Type2 Inactive DFGout 16.2978 10.4066 BBAminus -139.81, -179.58 -147.15, 104.1 -62.76, -35.23 278.0, 81.24 49.83, -115.81 in-in in 7.688 Saltbr-in 2.7024 HRD-in -69.78, -53.4 80.29, -13.23 in-out-in SNCioi out-in ActLoopNT-out 16.6043 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -122.57, 101.18 APE9-dihe-in -117.98, 151.43 APE8-dihe-in -83.84, 67.65 APE8-rot-na 33.5 APE67-dihe-in -63.86, -15.23 -50.06, -43.24 APE12-dist-na 16.889 APE11-dist-na 13.6286 APE10-dist-na 11.4181 APE9-dist-in 7.998 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.01 0.202 0.222 A 328.0 297.0 6 30 30 0 [[589, 926]] 1.0 6gql Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLB P10721 577 931 976.0 F8B:61001 Type2 Inactive DFGout 16.337 10.4783 BBAminus -138.32, -179.86 -148.07, 104.2 -62.14, -34.67 277.43, 81.68 50.68, -116.78 in-in in 7.7307 Saltbr-in 2.7414 HRD-in -68.79, -54.39 79.8, -13.05 in-out-out SNCioo out-out ActLoopNT-out 16.5368 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -117.3, 101.37 APE9-dihe-in -120.57, 151.18 APE8-dihe-in -84.13, 66.79 APE8-rot-na 32.76 APE67-dihe-in -64.17, -15.21 -49.48, -43.05 APE12-dist-na 17.1643 APE11-dist-na 13.913 APE10-dist-na 11.5187 APE9-dist-out 8.0601 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.01 0.202 0.222 B 328.0 286.0 8 30 30 0 [[589, 926]] 1.0 6gql Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: F8B

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name