Ligand: EX6

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 7T4UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKG1 KGP1_HUMAN 7T4UA Q13976 205 671 671.0 EX6:69901 Allosteric Inactive DFGin 5.8928 14.5109 ABAminus -110.98, -36.23 -113.94, 119.68 -109.65, 38.15 284.57, 73.72 -68.19, -46.47 in-in in 9.7533 Saltbr-in 2.9444 HRD-in -80.27, -49.41 62.96, -11.31 in-in-in SNCiii in-in ActLoopNT-in 2.9436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.82, 170.87 APE9-dihe-na 95.36, 163.3 APE8-dihe-in -65.83, 127.77 APE8-rot-in 297.19 APE67-dihe-in -61.65, -25.18 -50.5, -36.94 APE12-dist-in 8.3016 APE11-dist-in 11.5495 APE10-dist-in 5.8864 APE9-dist-in 5.0426 None TPO517 TPO517 XRAY 1.99 0.216 0.26 A 469.0 467.0 0 27 27 0 [[360, 619]] 1.0 7t4u AGC_PRKG1_HUMAN AGC 6.4e-84 287.2 1.0 260.0 260.0 501 502 503 505 507 390 409 413 481 483 482 484.0 540 528 523 522 521 520 519 518 517 439 cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4UB Q13976 205 671 671.0 EX6:69901 Allosteric Inactive DFGin 5.8817 14.6709 ABAminus -116.42, -27.15 -112.65, 115.98 -107.16, 33.12 284.12, 70.33 -62.23, -46.18 in-in in 9.7607 Saltbr-in 2.9206 HRD-in -79.97, -49.4 62.99, -11.71 in-in-in SNCiii in-in ActLoopNT-in 2.9244 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.62, 162.77 APE9-dihe-na 104.48, 162.22 APE8-dihe-in -65.39, 128.54 APE8-rot-in 296.86 APE67-dihe-in -62.65, -24.95 -50.24, -36.77 APE12-dist-in 8.2598 APE11-dist-in 11.5735 APE10-dist-in 5.9624 APE9-dist-in 5.0144 None TPO517 TPO517 XRAY 1.99 0.216 0.26 B 469.0 461.0 0 27 27 0 [[360, 619]] 1.0 7t4u AGC_PRKG1_HUMAN AGC 6.4e-84 287.2 1.0 260.0 260.0 501 502 503 505 507 390 409 413 481 483 482 484.0 540 528 523 522 521 520 519 518 517 439 cGMP-dependent protein kinase 1

Ligand: EX6

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 7T4UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKG1 KGP1_HUMAN 7T4UA Q13976 205 671 671.0 EX6:69901 Allosteric Inactive DFGin 5.8928 14.5109 ABAminus -110.98, -36.23 -113.94, 119.68 -109.65, 38.15 284.57, 73.72 -68.19, -46.47 in-in in 9.7533 Saltbr-in 2.9444 HRD-in -80.27, -49.41 62.96, -11.31 in-in-in SNCiii in-in ActLoopNT-in 2.9436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.82, 170.87 APE9-dihe-na 95.36, 163.3 APE8-dihe-in -65.83, 127.77 APE8-rot-in 297.19 APE67-dihe-in -61.65, -25.18 -50.5, -36.94 APE12-dist-in 8.3016 APE11-dist-in 11.5495 APE10-dist-in 5.8864 APE9-dist-in 5.0426 None TPO517 TPO517 XRAY 1.99 0.216 0.26 A 469.0 467.0 0 27 27 0 [[360, 619]] 1.0 7t4u Homo sapiens AGC_PRKG1_HUMAN AGC 6.4e-84 287.2 1.0 260.0 260.0 501 502 503 505 507 390 409 413 481 483 482 484.0 540 528 523 522 521 520 519 518 517 439 cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4UB Q13976 205 671 671.0 EX6:69901 Allosteric Inactive DFGin 5.8817 14.6709 ABAminus -116.42, -27.15 -112.65, 115.98 -107.16, 33.12 284.12, 70.33 -62.23, -46.18 in-in in 9.7607 Saltbr-in 2.9206 HRD-in -79.97, -49.4 62.99, -11.71 in-in-in SNCiii in-in ActLoopNT-in 2.9244 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.62, 162.77 APE9-dihe-na 104.48, 162.22 APE8-dihe-in -65.39, 128.54 APE8-rot-in 296.86 APE67-dihe-in -62.65, -24.95 -50.24, -36.77 APE12-dist-in 8.2598 APE11-dist-in 11.5735 APE10-dist-in 5.9624 APE9-dist-in 5.0144 None TPO517 TPO517 XRAY 1.99 0.216 0.26 B 469.0 461.0 0 27 27 0 [[360, 619]] 1.0 7t4u Homo sapiens AGC_PRKG1_HUMAN AGC 6.4e-84 287.2 1.0 260.0 260.0 501 502 503 505 507 390 409 413 481 483 482 484.0 540 528 523 522 521 520 519 518 517 439 cGMP-dependent protein kinase 1

Ligand: EX6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name