Ligand: DWT

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6FNJA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EPHA2 EPHA2_HUMAN 6FNGA 1.038 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_niiai APEdist_aaai DWT Type2 599 - 897 0 None None Ephrin type-A receptor 2
TYR EPHB4 EPHB4_HUMAN 6FNJA 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNJB 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4

Ligand: DWT

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6FNJA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EPHA2 EPHA2_HUMAN 6FNGA 1.038 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_niiai APEdist_aaai DWT Type2 599 - 897 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNJA 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNJB 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens

Ligand: DWT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism