Ligand: DJK

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2J5FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 2J5FA P00533 696 1020 1210.0 DJK:3021 Type1 None DFGin 5.657 14.3839 BLAminus -144.79, -170.55 64.0, 79.04 -97.73, 24.0 296.97, 99.2 -43.96, -47.9 in-in in 8.2671 Saltbr-in 2.8134 HRD-in -61.54, -44.58 69.15, -3.0 in-in-none SNCiin in-none ActLoopNT-in 2.6363 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 173.56 APE9-dihe-in -112.83, 120.26 APE8-dihe-in -93.5, 101.2 APE8-rot-na 33.0 APE67-dihe-in -64.88, -16.77 -72.19, -43.23 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.2266 APE9-dist-in 7.1462 None None None XRAY 3.0 0.194 0.246 A 327.0 309.0 8 30 22 8 [[712, 970]] 1.0 2j5f TYR_EGFR_HUMAN TYR 1e-87 299.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LQMA P00533 697 1019 1210.0 DJK:1101 Type1 Active DFGin 5.9785 14.5402 BLAminus -148.3, -172.91 62.11, 72.19 -94.6, 21.41 296.71, 99.46 -60.17, -37.69 in-in in 8.2189 Saltbr-in 2.8311 HRD-in -68.88, -49.63 72.39, 3.25 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.81, 131.0 APE9-dihe-in -102.62, 141.96 APE8-dihe-in -82.36, 88.32 APE8-rot-na 26.08 APE67-dihe-in -70.52, -7.71 -65.57, -41.89 APE12-dist-na 999.0 APE11-dist-na 11.5014 APE10-dist-na 12.1014 APE9-dist-in 7.5182 L858R None None XRAY 2.5 0.187 0.228 A 331.0 305.0 10 30 23 7 [[712, 970]] 1.0 4lqm TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: DJK

Total number of chains: 6
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% 2J5FA
DFGin None 1 16.7% 2HWPA
DFGinter None 1 16.7% 3LOKB
None None 1 16.7% 2HWPB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SRC SRC_CHICK 3LOKA P00523 257 533 533.0 DJK:1345 Type1 None DFGin 6.9718 15.1897 BLAminus -142.27, -178.52 61.56, 59.71 -73.15, 15.81 291.17, 75.02 7.94, -78.53 out-none out 12.5675 Saltbr-none 999.0 HRD-in -84.72, -53.13 84.0, -29.45 none-in-none SNCnin in-none ActLoopNT-in 2.9714 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -21.86 APE8-rot-na 353.04 APE67-dihe-in -78.27, -23.24 -85.98, 1.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T338M,S345C None None XRAY 2.48 0.225 0.286 A 286.0 248.0 29 29 15 14 [[267, 518]] 1.0 3lok Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 2HWPA P00523 256 533 533.0 DJK:1345 Type1 Inactive DFGin 4.9448 11.4913 None -149.7, 174.68 63.8, 24.74 24.42, 999.0 327.73, 96.53 999.0, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -76.7, -56.82 88.65, -21.99 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 140.02 APE8-dihe-in -78.72, 120.33 APE8-rot-na 32.38 APE67-dihe-in -69.35, -32.46 -64.49, -21.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.5907 S345C None None XRAY 2.48 0.228 0.276 A 286.0 245.0 33 29 11 18 [[267, 518]] 1.0 2hwp Gallus gallus TYR_SRC_CHICK TYR 4.5e-94 320.5 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 3LOKB P00523 258 533 533.0 DJK:1345 Type1 Inactive DFGinter 8.9976 7.3434 None -159.95, 165.79 -130.83, 138.21 -129.88, -38.43 343.22, 92.96 171.11, -62.33 none-none none 999.0 Saltbr-none 999.0 HRD-in -82.23, -48.63 85.47, -21.61 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -14.67 APE8-rot-na 348.92 APE67-dihe-in -76.3, -19.85 -81.25, -4.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T338M,S345C None None XRAY 2.48 0.225 0.286 B 286.0 242.0 34 29 12 17 [[267, 518]] 1.0 3lok Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 2HWPB P00523 258 533 533.0 DJK:1345 Type1 Inactive None 999.0 999.0 None -117.43, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -86.38, -51.49 81.58, -23.56 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 37.35 APE8-dihe-in -83.23, 97.91 APE8-rot-na 31.48 APE67-dihe-in -57.85, -20.33 -55.14, -44.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.7092 S345C None None XRAY 2.48 0.228 0.276 B 286.0 239.0 37 29 9 20 [[267, 518]] 1.0 2hwp Gallus gallus TYR_SRC_CHICK TYR 4.5e-94 320.5 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR EGFR EGFR_HUMAN 2J5FA P00533 696 1020 1210.0 DJK:3021 Type1 None DFGin 5.657 14.3839 BLAminus -144.79, -170.55 64.0, 79.04 -97.73, 24.0 296.97, 99.2 -43.96, -47.9 in-in in 8.2671 Saltbr-in 2.8134 HRD-in -61.54, -44.58 69.15, -3.0 in-in-none SNCiin in-none ActLoopNT-in 2.6363 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 173.56 APE9-dihe-in -112.83, 120.26 APE8-dihe-in -93.5, 101.2 APE8-rot-na 33.0 APE67-dihe-in -64.88, -16.77 -72.19, -43.23 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.2266 APE9-dist-in 7.1462 None None None XRAY 3.0 0.194 0.246 A 327.0 309.0 8 30 22 8 [[712, 970]] 1.0 2j5f Homo sapiens TYR_EGFR_HUMAN TYR 1e-87 299.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LQMA P00533 697 1019 1210.0 DJK:1101 Type1 Active DFGin 5.9785 14.5402 BLAminus -148.3, -172.91 62.11, 72.19 -94.6, 21.41 296.71, 99.46 -60.17, -37.69 in-in in 8.2189 Saltbr-in 2.8311 HRD-in -68.88, -49.63 72.39, 3.25 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.81, 131.0 APE9-dihe-in -102.62, 141.96 APE8-dihe-in -82.36, 88.32 APE8-rot-na 26.08 APE67-dihe-in -70.52, -7.71 -65.57, -41.89 APE12-dist-na 999.0 APE11-dist-na 11.5014 APE10-dist-na 12.1014 APE9-dist-in 7.5182 L858R None None XRAY 2.5 0.187 0.228 A 331.0 305.0 10 30 23 7 [[712, 970]] 1.0 4lqm Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: DJK

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 25.0% 3LOKA
DFGin None 1 25.0% 2HWPA
DFGinter None 1 25.0% 3LOKB
None None 1 25.0% 2HWPB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SRC SRC_CHICK 3LOKA P00523 257 533 533.0 DJK:1345 Type1 None DFGin 6.9718 15.1897 BLAminus -142.27, -178.52 61.56, 59.71 -73.15, 15.81 291.17, 75.02 7.94, -78.53 out-none out 12.5675 Saltbr-none 999.0 HRD-in -84.72, -53.13 84.0, -29.45 none-in-none SNCnin in-none ActLoopNT-in 2.9714 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -21.86 APE8-rot-na 353.04 APE67-dihe-in -78.27, -23.24 -85.98, 1.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T338M,S345C None None XRAY 2.48 0.225 0.286 A 286.0 248.0 29 29 15 14 [[267, 518]] 1.0 3lok Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 2HWPA P00523 256 533 533.0 DJK:1345 Type1 Inactive DFGin 4.9448 11.4913 None -149.7, 174.68 63.8, 24.74 24.42, 999.0 327.73, 96.53 999.0, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -76.7, -56.82 88.65, -21.99 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 140.02 APE8-dihe-in -78.72, 120.33 APE8-rot-na 32.38 APE67-dihe-in -69.35, -32.46 -64.49, -21.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.5907 S345C None None XRAY 2.48 0.228 0.276 A 286.0 245.0 33 29 11 18 [[267, 518]] 1.0 2hwp Gallus gallus TYR_SRC_CHICK TYR 4.5e-94 320.5 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 3LOKB P00523 258 533 533.0 DJK:1345 Type1 Inactive DFGinter 8.9976 7.3434 None -159.95, 165.79 -130.83, 138.21 -129.88, -38.43 343.22, 92.96 171.11, -62.33 none-none none 999.0 Saltbr-none 999.0 HRD-in -82.23, -48.63 85.47, -21.61 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -14.67 APE8-rot-na 348.92 APE67-dihe-in -76.3, -19.85 -81.25, -4.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T338M,S345C None None XRAY 2.48 0.225 0.286 B 286.0 242.0 34 29 12 17 [[267, 518]] 1.0 3lok Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_CHICK 2HWPB P00523 258 533 533.0 DJK:1345 Type1 Inactive None 999.0 999.0 None -117.43, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -86.38, -51.49 81.58, -23.56 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 37.35 APE8-dihe-in -83.23, 97.91 APE8-rot-na 31.48 APE67-dihe-in -57.85, -20.33 -55.14, -44.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.7092 S345C None None XRAY 2.48 0.228 0.276 B 286.0 239.0 37 29 9 20 [[267, 518]] 1.0 2hwp Gallus gallus TYR_SRC_CHICK TYR 4.5e-94 320.5 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src