Ligand: BR2

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 3SKCB
DFGin BLBminus 1 50.0% 3SKCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf

Ligand: BR2

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 3SKCB
DFGin BLBminus 1 50.0% 3SKCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens

Ligand: BR2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism