| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_CRIGR | 5OTGA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.6641 | 14.8724 | ABAminus | -116.07, -34.14 | -101.63, 135.19 | -132.51, 30.55 | 284.27, 81.94 | -65.58, -28.86 | in-in | in | 9.2076 | Saltbr-in | 2.8838 | HRD-in | -87.0, -54.6 | 75.88, 1.07 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9513 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -156.1, 159.53 | APE9-dihe-na | 126.93, -164.36 | APE8-dihe-in | -118.42, 136.98 | APE8-rot-in | 301.94 | APE67-dihe-in | -61.55, -22.37 | -50.07, -49.22 | APE12-dist-in | 8.3277 | APE11-dist-in | 11.5661 | APE10-dist-in | 5.9649 | APE9-dist-in | 3.7403 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.73 | 0.187 | 0.206 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 5otg | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_CRIGR | 5OUCA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.5448 | 14.6897 | ABAminus | -118.72, -31.35 | -98.66, 124.06 | -126.19, 22.18 | 285.25, 84.4 | -64.9, -29.38 | in-none | in | 9.0152 | Saltbr-none | 999.0 | HRD-in | -89.21, -57.44 | 74.92, -2.84 | none-in-in | SNCnii | in-in | ActLoopNT-in | 2.9042 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.91, 152.91 | APE9-dihe-na | 134.96, -159.63 | APE8-dihe-in | -125.22, 135.43 | APE8-rot-in | 300.15 | APE67-dihe-in | -61.76, -25.06 | -48.4, -50.36 | APE12-dist-in | 8.2727 | APE11-dist-in | 11.4814 | APE10-dist-in | 5.9359 | APE9-dist-in | 4.0149 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.46 | 0.151 | 0.175 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 5ouc | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_CRIGR | 6I2HA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.5671 | 14.8085 | ABAminus | -115.56, -38.67 | -109.61, 104.13 | -103.25, 25.9 | 285.61, 77.71 | -66.17, -17.47 | in-in | in | 8.9865 | Saltbr-in | 2.9304 | HRD-in | -83.42, -55.73 | 70.56, 10.93 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8462 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -157.42, 160.46 | APE9-dihe-na | 121.97, -162.48 | APE8-dihe-in | -116.28, 135.78 | APE8-rot-in | 298.33 | APE67-dihe-in | -60.57, -22.98 | -48.67, -52.6 | APE12-dist-in | 8.1576 | APE11-dist-in | 11.371 | APE10-dist-in | 5.6959 | APE9-dist-in | 3.5478 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.68 | 0.182 | 0.202 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 6i2h | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_CRIGR | 5OTGA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.6641 | 14.8724 | ABAminus | -116.07, -34.14 | -101.63, 135.19 | -132.51, 30.55 | 284.27, 81.94 | -65.58, -28.86 | in-in | in | 9.2076 | Saltbr-in | 2.8838 | HRD-in | -87.0, -54.6 | 75.88, 1.07 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9513 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -156.1, 159.53 | APE9-dihe-na | 126.93, -164.36 | APE8-dihe-in | -118.42, 136.98 | APE8-rot-in | 301.94 | APE67-dihe-in | -61.55, -22.37 | -50.07, -49.22 | APE12-dist-in | 8.3277 | APE11-dist-in | 11.5661 | APE10-dist-in | 5.9649 | APE9-dist-in | 3.7403 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.73 | 0.187 | 0.206 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 5otg | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_CRIGR | 5OUCA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.5448 | 14.6897 | ABAminus | -118.72, -31.35 | -98.66, 124.06 | -126.19, 22.18 | 285.25, 84.4 | -64.9, -29.38 | in-none | in | 9.0152 | Saltbr-none | 999.0 | HRD-in | -89.21, -57.44 | 74.92, -2.84 | none-in-in | SNCnii | in-in | ActLoopNT-in | 2.9042 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.91, 152.91 | APE9-dihe-na | 134.96, -159.63 | APE8-dihe-in | -125.22, 135.43 | APE8-rot-in | 300.15 | APE67-dihe-in | -61.76, -25.06 | -48.4, -50.36 | APE12-dist-in | 8.2727 | APE11-dist-in | 11.4814 | APE10-dist-in | 5.9359 | APE9-dist-in | 4.0149 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.46 | 0.151 | 0.175 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 5ouc | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_CRIGR | 6I2HA | P25321 | 1 | 351 | 351.0 | AO8:60401 | Type1 | Inactive | DFGin | 6.5671 | 14.8085 | ABAminus | -115.56, -38.67 | -109.61, 104.13 | -103.25, 25.9 | 285.61, 77.71 | -66.17, -17.47 | in-in | in | 8.9865 | Saltbr-in | 2.9304 | HRD-in | -83.42, -55.73 | 70.56, 10.93 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8462 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -157.42, 160.46 | APE9-dihe-na | 121.97, -162.48 | APE8-dihe-in | -116.28, 135.78 | APE8-rot-in | 298.33 | APE67-dihe-in | -60.57, -22.98 | -48.67, -52.6 | APE12-dist-in | 8.1576 | APE11-dist-in | 11.371 | APE10-dist-in | 5.6959 | APE9-dist-in | 3.5478 | None | SEP11,SEP140,TPO198,SEP339 | SEP11,SEP140,TPO198,SEP339 | XRAY | 1.68 | 0.182 | 0.202 | A | 353.0 | 351.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 6i2h | Cricetulus griseus | AGC_PRKACA_CRIGR | AGC | 6.6e-95 | 323.2 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |