Ligand: A1ESX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VMBA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 9VMBA P22607 456 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.993 13.461 BLAplus DFGAsp-rot-out -106.5175, 161.6879 65.3472, 18.46 293.7428, -21.3049 -70.1659, -20.2448 57.7617, 91.439 -90.0125, 3.5321 in-in in 8.114 Saltbr-in 3.154 HRD-in -73.0442, -49.8537 77.8647, -11.6549 in-out-out SNCioo out-out ActLoopNT-out 7.526 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -152.7604, 163.4923 APE9-dihe-in -109.8641, 99.2708 APE8-dihe-out -57.3812, -21.1375 APE8-rot-na 333.2281 APE67-dihe-in -72.5898, -10.0313 -56.6744, -26.6672 APE12-dist-na 15.764 APE11-dist-na 19.999 APE10-dist-na 18.055 APE9-dist-out 11.148 None None None XRAY 1.97 0.19 0.237 A 292 287 2 0 0 0 [[472, 750]] 1.0 9vmb TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBB P22607 456 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.918 13.334 BLAplus DFGAsp-rot-out -101.2362, 162.3019 65.7035, 22.9263 296.0175, -18.1175 -75.1338, -16.684 57.728, 90.9936 -87.9579, -1.2468 in-in in 8.139 Saltbr-in 2.932 HRD-in -80.3523, -46.5517 70.8057, -7.6489 in-out-out SNCioo out-out ActLoopNT-out 7.213 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -154.8117, 163.1472 APE9-dihe-in -110.4807, 104.3122 APE8-dihe-out -59.7288, -18.7285 APE8-rot-na 334.721 APE67-dihe-in -68.6335, -11.7253 -64.2068, -25.2113 APE12-dist-na 16.031 APE11-dist-na 20.139 APE10-dist-na 18.09 APE9-dist-out 11.151 None None None XRAY 1.97 0.19 0.237 B 292 287 2 0 0 0 [[472, 750]] 1.0 9vmb TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBC P22607 457 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.945 13.666 BLAplus DFGAsp-rot-out -103.8136, 162.5884 63.5687, 24.7591 293.6162, -20.9054 -75.1988, -20.3203 56.9995, 90.1495 -91.5147, 3.3859 in-in in 8.479 Saltbr-in 3.31 HRD-in -72.8221, -49.2111 77.839, -8.105 in-out-out SNCioo out-out ActLoopNT-out 7.476 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -157.0324, 160.7269 APE9-dihe-in -107.8221, 103.0352 APE8-dihe-out -59.0895, -17.7937 APE8-rot-na 339.4939 APE67-dihe-in -70.5257, -10.852 -59.7611, -29.5081 APE12-dist-na 15.382 APE11-dist-na 19.602 APE10-dist-na 17.694 APE9-dist-out 11.087 None None None XRAY 1.97 0.19 0.237 C 292 286 2 0 0 0 [[472, 750]] 1.0 9vmb TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBD P22607 462 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.791 13.46 BLAplus DFGAsp-rot-out -100.7828, 162.3753 66.1417, 19.9883 295.7498, -20.8087 -67.6844, -21.8861 57.61, 88.7193 -92.2668, 3.4935 in-out in 8.295 Saltbr-out 3.757 HRD-in -74.0736, -49.8159 78.6982, -9.5659 out-out-out SNCooo out-out ActLoopNT-out 7.159 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -147.9897, 158.6846 APE9-dihe-in -103.9422, 104.6784 APE8-dihe-out -56.8069, -24.4311 APE8-rot-na 333.5062 APE67-dihe-in -75.6433, -10.8102 -61.0327, -20.764 APE12-dist-na 15.923 APE11-dist-na 20.119 APE10-dist-na 17.988 APE9-dist-out 11.1 None None None XRAY 1.97 0.19 0.237 D 292 281 2 0 0 0 [[472, 750]] 1.0 9vmb TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1ESX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VMBA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 9VMBA P22607 456 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.993 13.461 BLAplus DFGAsp-rot-out -106.5175, 161.6879 65.3472, 18.46 293.7428, -21.3049 -70.1659, -20.2448 57.7617, 91.439 -90.0125, 3.5321 in-in in 8.114 Saltbr-in 3.154 HRD-in -73.0442, -49.8537 77.8647, -11.6549 in-out-out SNCioo out-out ActLoopNT-out 7.526 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -152.7604, 163.4923 APE9-dihe-in -109.8641, 99.2708 APE8-dihe-out -57.3812, -21.1375 APE8-rot-na 333.2281 APE67-dihe-in -72.5898, -10.0313 -56.6744, -26.6672 APE12-dist-na 15.764 APE11-dist-na 19.999 APE10-dist-na 18.055 APE9-dist-out 11.148 None None None XRAY 1.97 0.19 0.237 A 292 287 2 0 0 0 [[472, 750]] 1.0 9vmb Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBB P22607 456 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.918 13.334 BLAplus DFGAsp-rot-out -101.2362, 162.3019 65.7035, 22.9263 296.0175, -18.1175 -75.1338, -16.684 57.728, 90.9936 -87.9579, -1.2468 in-in in 8.139 Saltbr-in 2.932 HRD-in -80.3523, -46.5517 70.8057, -7.6489 in-out-out SNCioo out-out ActLoopNT-out 7.213 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -154.8117, 163.1472 APE9-dihe-in -110.4807, 104.3122 APE8-dihe-out -59.7288, -18.7285 APE8-rot-na 334.721 APE67-dihe-in -68.6335, -11.7253 -64.2068, -25.2113 APE12-dist-na 16.031 APE11-dist-na 20.139 APE10-dist-na 18.09 APE9-dist-out 11.151 None None None XRAY 1.97 0.19 0.237 B 292 287 2 0 0 0 [[472, 750]] 1.0 9vmb Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBC P22607 457 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.945 13.666 BLAplus DFGAsp-rot-out -103.8136, 162.5884 63.5687, 24.7591 293.6162, -20.9054 -75.1988, -20.3203 56.9995, 90.1495 -91.5147, 3.3859 in-in in 8.479 Saltbr-in 3.31 HRD-in -72.8221, -49.2111 77.839, -8.105 in-out-out SNCioo out-out ActLoopNT-out 7.476 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -157.0324, 160.7269 APE9-dihe-in -107.8221, 103.0352 APE8-dihe-out -59.0895, -17.7937 APE8-rot-na 339.4939 APE67-dihe-in -70.5257, -10.852 -59.7611, -29.5081 APE12-dist-na 15.382 APE11-dist-na 19.602 APE10-dist-na 17.694 APE9-dist-out 11.087 None None None XRAY 1.97 0.19 0.237 C 292 286 2 0 0 0 [[472, 750]] 1.0 9vmb Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBD P22607 462 756 806.0 A1ESX:801 Type1 Inactive DFGin 4.791 13.46 BLAplus DFGAsp-rot-out -100.7828, 162.3753 66.1417, 19.9883 295.7498, -20.8087 -67.6844, -21.8861 57.61, 88.7193 -92.2668, 3.4935 in-out in 8.295 Saltbr-out 3.757 HRD-in -74.0736, -49.8159 78.6982, -9.5659 out-out-out SNCooo out-out ActLoopNT-out 7.159 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -147.9897, 158.6846 APE9-dihe-in -103.9422, 104.6784 APE8-dihe-out -56.8069, -24.4311 APE8-rot-na 333.5062 APE67-dihe-in -75.6433, -10.8102 -61.0327, -20.764 APE12-dist-na 15.923 APE11-dist-na 20.119 APE10-dist-na 17.988 APE9-dist-out 11.1 None None None XRAY 1.97 0.19 0.237 D 292 281 2 0 0 0 [[472, 750]] 1.0 9vmb Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1ESX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name