Ligand: A1ESW

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VM9A
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 9VM9A P22607 456 756 806.0 A1ESW:801 Type1 Inactive DFGin 4.966 13.492 BLAplus DFGAsp-rot-out -119.2253, 164.0599 63.1421, 28.0452 298.4088, -20.5723 -80.6137, -19.722 58.8265, 88.3498 -89.4979, 3.838 in-in in 8.227 Saltbr-in 3.087 HRD-in -83.5015, -38.9421 67.609, -4.9778 in-out-out SNCioo out-out ActLoopNT-out 7.488 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -161.4206, 160.008 APE9-dihe-in -107.118, 107.4877 APE8-dihe-out -62.9034, -10.7817 APE8-rot-na 339.842 APE67-dihe-in -73.7411, -10.7298 -67.7033, -23.1684 APE12-dist-na 16.035 APE11-dist-na 20.242 APE10-dist-na 18.306 APE9-dist-out 11.034 None None None XRAY 2.65 0.262 0.312 A 292 287 2 0 0 0 [[472, 750]] 1.0 9vm9 TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9B P22607 457 755 806.0 A1ESW:801 Type1 Inactive DFGin 4.897 13.418 BLAplus DFGAsp-rot-out -118.1146, 165.3887 61.3627, 30.6061 300.2288, -39.0485 -82.5158, -20.0989 61.779, 89.971 -89.4214, 0.2931 in-out in 8.194 Saltbr-out 4.343 HRD-in -78.6959, -44.4486 76.8665, -18.6531 out-out-out SNCooo out-out ActLoopNT-out 7.085 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -164.1861, 155.5897 APE9-dihe-in -100.8219, 112.393 APE8-dihe-out -62.6805, -15.6899 APE8-rot-na 338.614 APE67-dihe-in -73.9513, -16.6434 -66.7504, -20.5086 APE12-dist-na 15.925 APE11-dist-na 20.12 APE10-dist-na 18.159 APE9-dist-out 10.971 None None None XRAY 2.65 0.262 0.312 B 292 285 2 0 0 0 [[472, 750]] 1.0 9vm9 TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9C P22607 462 756 806.0 A1ESW:801 Type1 Inactive DFGin 4.981 13.216 BLAplus DFGAsp-rot-out -117.2651, 166.7429 62.5729, 25.3486 294.8151, -23.2774 -78.3678, -24.8213 55.9088, 91.3153 -86.7896, 3.5439 in-out in 8.16 Saltbr-out 4.018 HRD-in -78.4924, -39.3464 68.6842, -7.6966 out-out-out SNCooo out-out ActLoopNT-out 7.457 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -158.0344, 156.8491 APE9-dihe-in -101.6007, 111.3298 APE8-dihe-out -63.9614, -13.0871 APE8-rot-na 340.3288 APE67-dihe-in -75.3695, -10.2261 -66.4686, -23.6326 APE12-dist-na 15.991 APE11-dist-na 20.237 APE10-dist-na 18.228 APE9-dist-out 11.099 None None None XRAY 2.65 0.262 0.312 C 292 281 2 0 0 0 [[472, 750]] 1.0 9vm9 TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9D P22607 459 756 806.0 A1ESW:802 Type1 Inactive DFGin 5.041 13.235 BLAplus DFGAsp-rot-out -113.9306, 165.2223 61.6624, 22.0486 298.8167, -19.0768 -73.4743, -22.6442 57.5347, 87.6331 -90.2727, 1.583 in-none in 8.154 Saltbr-none 999.0 HRD-in -71.1771, -50.6322 76.5196, -3.1321 none-out-out SNCnoo out-out ActLoopNT-out 7.536 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -152.0562, 156.2583 APE9-dihe-in -103.8127, 110.8616 APE8-dihe-out -64.3171, -15.4813 APE8-rot-na 338.7707 APE67-dihe-in -74.9476, -13.3888 -65.6453, -22.3392 APE12-dist-na 15.838 APE11-dist-na 20.012 APE10-dist-na 17.941 APE9-dist-out 10.904 None None None XRAY 2.65 0.262 0.312 D 292 284 2 0 0 0 [[472, 750]] 1.0 9vm9 TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1ESW

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VM9A
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 9VM9A P22607 456 756 806.0 A1ESW:801 Type1 Inactive DFGin 4.966 13.492 BLAplus DFGAsp-rot-out -119.2253, 164.0599 63.1421, 28.0452 298.4088, -20.5723 -80.6137, -19.722 58.8265, 88.3498 -89.4979, 3.838 in-in in 8.227 Saltbr-in 3.087 HRD-in -83.5015, -38.9421 67.609, -4.9778 in-out-out SNCioo out-out ActLoopNT-out 7.488 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -161.4206, 160.008 APE9-dihe-in -107.118, 107.4877 APE8-dihe-out -62.9034, -10.7817 APE8-rot-na 339.842 APE67-dihe-in -73.7411, -10.7298 -67.7033, -23.1684 APE12-dist-na 16.035 APE11-dist-na 20.242 APE10-dist-na 18.306 APE9-dist-out 11.034 None None None XRAY 2.65 0.262 0.312 A 292 287 2 0 0 0 [[472, 750]] 1.0 9vm9 Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9B P22607 457 755 806.0 A1ESW:801 Type1 Inactive DFGin 4.897 13.418 BLAplus DFGAsp-rot-out -118.1146, 165.3887 61.3627, 30.6061 300.2288, -39.0485 -82.5158, -20.0989 61.779, 89.971 -89.4214, 0.2931 in-out in 8.194 Saltbr-out 4.343 HRD-in -78.6959, -44.4486 76.8665, -18.6531 out-out-out SNCooo out-out ActLoopNT-out 7.085 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -164.1861, 155.5897 APE9-dihe-in -100.8219, 112.393 APE8-dihe-out -62.6805, -15.6899 APE8-rot-na 338.614 APE67-dihe-in -73.9513, -16.6434 -66.7504, -20.5086 APE12-dist-na 15.925 APE11-dist-na 20.12 APE10-dist-na 18.159 APE9-dist-out 10.971 None None None XRAY 2.65 0.262 0.312 B 292 285 2 0 0 0 [[472, 750]] 1.0 9vm9 Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9C P22607 462 756 806.0 A1ESW:801 Type1 Inactive DFGin 4.981 13.216 BLAplus DFGAsp-rot-out -117.2651, 166.7429 62.5729, 25.3486 294.8151, -23.2774 -78.3678, -24.8213 55.9088, 91.3153 -86.7896, 3.5439 in-out in 8.16 Saltbr-out 4.018 HRD-in -78.4924, -39.3464 68.6842, -7.6966 out-out-out SNCooo out-out ActLoopNT-out 7.457 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -158.0344, 156.8491 APE9-dihe-in -101.6007, 111.3298 APE8-dihe-out -63.9614, -13.0871 APE8-rot-na 340.3288 APE67-dihe-in -75.3695, -10.2261 -66.4686, -23.6326 APE12-dist-na 15.991 APE11-dist-na 20.237 APE10-dist-na 18.228 APE9-dist-out 11.099 None None None XRAY 2.65 0.262 0.312 C 292 281 2 0 0 0 [[472, 750]] 1.0 9vm9 Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9D P22607 459 756 806.0 A1ESW:802 Type1 Inactive DFGin 5.041 13.235 BLAplus DFGAsp-rot-out -113.9306, 165.2223 61.6624, 22.0486 298.8167, -19.0768 -73.4743, -22.6442 57.5347, 87.6331 -90.2727, 1.583 in-none in 8.154 Saltbr-none 999.0 HRD-in -71.1771, -50.6322 76.5196, -3.1321 none-out-out SNCnoo out-out ActLoopNT-out 7.536 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -152.0562, 156.2583 APE9-dihe-in -103.8127, 110.8616 APE8-dihe-out -64.3171, -15.4813 APE8-rot-na 338.7707 APE67-dihe-in -74.9476, -13.3888 -65.6453, -22.3392 APE12-dist-na 15.838 APE11-dist-na 20.012 APE10-dist-na 17.941 APE9-dist-out 10.904 None None None XRAY 2.65 0.262 0.312 D 292 284 2 0 0 0 [[472, 750]] 1.0 9vm9 Homo sapiens TYR_FGFR3_HUMAN TYR 8.1e-105 355.8 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1ESW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name