Ligand: A1D6I

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8YHFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 8YHLA P36897 200 501 503.0 A1D6I:60601 Type1 Active DFGin 6.0207 13.0482 BLAminus -124.89, -169.46 42.91, 75.25 -91.67, 10.82 300.67, 10.41 -67.27, -22.16 in-in in 7.6986 Saltbr-in 2.9646 HRD-in -79.41, -52.59 75.07, -1.34 in-in-in SNCiii in-in ActLoopNT-in 2.9317 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -72.3, 155.92 APE9-dihe-na 107.61, -172.07 APE8-dihe-in -88.21, 123.34 APE8-rot-in 304.18 APE67-dihe-in -56.11, -38.82 -61.94, -38.97 APE12-dist-in 13.3426 APE11-dist-in 12.5182 APE10-dist-in 6.3143 APE9-dist-in 3.8164 None None None XRAY 1.47 0.165 0.193 A 306.0 302.0 0 32 32 0 [[205, 494]] 1.0 8yhl TKL_TGFBR1_HUMAN TKL 3.3e-85 291.7 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 8YHFA P36897 201 498 503.0 A1D6I:601 Type1 Active DFGin 6.0367 13.1516 BLAminus -127.63, -168.18 39.33, 73.78 -89.91, 13.29 302.44, 7.93 -62.86, -27.56 in-in in 7.7993 Saltbr-in 3.0294 HRD-in -79.9, -54.99 79.42, -3.09 in-in-in SNCiii in-in ActLoopNT-in 2.9537 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -84.79, -23.11 APE9-dihe-na -96.35, -152.57 APE8-dihe-in -84.18, 124.71 APE8-rot-in 302.64 APE67-dihe-in -56.72, -32.39 -61.45, -41.11 APE12-dist-in 13.1782 APE11-dist-in 12.22 APE10-dist-in 6.2179 APE9-dist-in 3.8345 None None None XRAY 1.4 0.167 0.192 A 343.0 298.0 0 32 32 0 [[205, 494]] 1.0 8yhf TKL_TGFBR1_HUMAN TKL 5e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

Ligand: A1D6I

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8YHFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 8YHLA P36897 200 501 503.0 A1D6I:60601 Type1 Active DFGin 6.0207 13.0482 BLAminus -124.89, -169.46 42.91, 75.25 -91.67, 10.82 300.67, 10.41 -67.27, -22.16 in-in in 7.6986 Saltbr-in 2.9646 HRD-in -79.41, -52.59 75.07, -1.34 in-in-in SNCiii in-in ActLoopNT-in 2.9317 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -72.3, 155.92 APE9-dihe-na 107.61, -172.07 APE8-dihe-in -88.21, 123.34 APE8-rot-in 304.18 APE67-dihe-in -56.11, -38.82 -61.94, -38.97 APE12-dist-in 13.3426 APE11-dist-in 12.5182 APE10-dist-in 6.3143 APE9-dist-in 3.8164 None None None XRAY 1.47 0.165 0.193 A 306.0 302.0 0 32 32 0 [[205, 494]] 1.0 8yhl Homo sapiens TKL_TGFBR1_HUMAN TKL 3.3e-85 291.7 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 8YHFA P36897 201 498 503.0 A1D6I:601 Type1 Active DFGin 6.0367 13.1516 BLAminus -127.63, -168.18 39.33, 73.78 -89.91, 13.29 302.44, 7.93 -62.86, -27.56 in-in in 7.7993 Saltbr-in 3.0294 HRD-in -79.9, -54.99 79.42, -3.09 in-in-in SNCiii in-in ActLoopNT-in 2.9537 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -84.79, -23.11 APE9-dihe-na -96.35, -152.57 APE8-dihe-in -84.18, 124.71 APE8-rot-in 302.64 APE67-dihe-in -56.72, -32.39 -61.45, -41.11 APE12-dist-in 13.1782 APE11-dist-in 12.22 APE10-dist-in 6.2179 APE9-dist-in 3.8345 None None None XRAY 1.4 0.167 0.192 A 343.0 298.0 0 32 32 0 [[205, 494]] 1.0 8yhf Homo sapiens TKL_TGFBR1_HUMAN TKL 5e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

Ligand: A1D6I

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name