Ligand: 8OU

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5Y5UA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR SYK KSYK_HUMAN 5Y5UA 2.14 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 8OU Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UB 2.14 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 8OU Type1 363 - 629 0 None None Tyrosine-protein kinase SYK

Ligand: 8OU

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5Y5UA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SYK KSYK_HUMAN 5Y5UA 2.14 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 8OU Type1 364 - 634 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 5Y5UB 2.14 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 8OU Type1 363 - 629 0 None None Tyrosine-protein kinase SYK Homo sapiens

Ligand: 8OU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism