Ligand: 8OU

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5Y5UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SYK KSYK_HUMAN 5Y5UA P43405 364 634 635.0 8OU:701 Type1 Active DFGin 6.4344 14.0988 BLAminus -136.65, 173.94 66.9, 89.62 -105.43, 28.84 296.27, 90.39 -60.97, -30.93 in-in in 7.9941 Saltbr-in 2.5848 HRD-in -70.93, -52.74 73.81, 2.31 in-in-in SNCiii in-in ActLoopNT-in 2.7997 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.85, 121.36 APE9-dihe-in -125.49, 151.88 APE8-dihe-in -80.17, 69.97 APE8-rot-na 36.19 APE67-dihe-in -65.59, -17.51 -56.34, -35.15 APE12-dist-na 13.3247 APE11-dist-na 10.8666 APE10-dist-na 11.8021 APE9-dist-in 7.2259 None None None XRAY 2.14 0.239 0.26 A 293.0 266.0 5 31 31 0 [[370, 628]] 1.0 5y5u TYR_SYK_HUMAN TYR 5.7e-90 307.1 5.0 260.0 256.0 511 512 513 515 517 402 420 424 491 493 492 494.0 554 542 537 536 535 534 533 532 531 449 Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UB P43405 363 629 635.0 8OU:701 Type1 None DFGin 6.3221 13.9991 BLAminus -136.83, 172.48 60.12, 69.06 -76.3, 17.06 301.14, 79.7 -45.71, -46.86 in-in in 7.647 Saltbr-in 2.7979 HRD-in -72.89, -51.34 74.65, -2.0 in-in-none SNCiin in-none ActLoopNT-in 2.8215 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 45.91 APE8-rot-na 27.44 APE67-dihe-in -59.42, -23.8 -55.69, -38.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.14 0.239 0.26 B 293.0 257.0 10 31 25 6 [[370, 628]] 1.0 5y5u TYR_SYK_HUMAN TYR 5.7e-90 307.1 5.0 260.0 256.0 511 512 513 515 517 402 420 424 491 493 492 494.0 554 542 537 536 535 534 533 532 531 449 Tyrosine-protein kinase SYK

Ligand: 8OU

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5Y5UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SYK KSYK_HUMAN 5Y5UA P43405 364 634 635.0 8OU:701 Type1 Active DFGin 6.4344 14.0988 BLAminus -136.65, 173.94 66.9, 89.62 -105.43, 28.84 296.27, 90.39 -60.97, -30.93 in-in in 7.9941 Saltbr-in 2.5848 HRD-in -70.93, -52.74 73.81, 2.31 in-in-in SNCiii in-in ActLoopNT-in 2.7997 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.85, 121.36 APE9-dihe-in -125.49, 151.88 APE8-dihe-in -80.17, 69.97 APE8-rot-na 36.19 APE67-dihe-in -65.59, -17.51 -56.34, -35.15 APE12-dist-na 13.3247 APE11-dist-na 10.8666 APE10-dist-na 11.8021 APE9-dist-in 7.2259 None None None XRAY 2.14 0.239 0.26 A 293.0 266.0 5 31 31 0 [[370, 628]] 1.0 5y5u Homo sapiens TYR_SYK_HUMAN TYR 5.7e-90 307.1 5.0 260.0 256.0 511 512 513 515 517 402 420 424 491 493 492 494.0 554 542 537 536 535 534 533 532 531 449 Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UB P43405 363 629 635.0 8OU:701 Type1 None DFGin 6.3221 13.9991 BLAminus -136.83, 172.48 60.12, 69.06 -76.3, 17.06 301.14, 79.7 -45.71, -46.86 in-in in 7.647 Saltbr-in 2.7979 HRD-in -72.89, -51.34 74.65, -2.0 in-in-none SNCiin in-none ActLoopNT-in 2.8215 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 45.91 APE8-rot-na 27.44 APE67-dihe-in -59.42, -23.8 -55.69, -38.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.14 0.239 0.26 B 293.0 257.0 10 31 25 6 [[370, 628]] 1.0 5y5u Homo sapiens TYR_SYK_HUMAN TYR 5.7e-90 307.1 5.0 260.0 256.0 511 512 513 515 517 402 420 424 491 493 492 494.0 554 542 537 536 535 534 533 532 531 449 Tyrosine-protein kinase SYK

Ligand: 8OU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name