Ligand: 8BV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5UIQC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5UIQA Q9NWZ3 164 459 460.0 8BV:501 Type1 Inactive DFGin 6.931 14.309 BLAminus -127.76, 177.14 59.33, 95.8 -119.34, 15.89 308.77, 95.83 -65.11, -29.47 in-out in 8.65 Saltbr-out 4.302 HRD-in -67.28, -50.5 79.56, -0.59 out-in-in SNCoii in-in ActLoopNT-in 2.805 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.14, 152.7 APE9-dihe-na 138.15, -166.94 APE8-dihe-in -116.13, 111.27 APE8-rot-in 312.43 APE67-dihe-in -63.93, -18.01 -42.44, -46.16 APE12-dist-in 9.869 APE11-dist-in 11.872 APE10-dist-in 6.442 APE9-dist-in 3.93 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 A 323 271 25 0 0 4 [[183, 456]] 1.0 5uiq TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQB Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.804 14.376 BLAminus -130.56, -176.5 54.94, 94.68 -118.91, 16.72 307.57, 95.93 -64.01, -29.62 in-out in 8.829 Saltbr-out 4.386 HRD-in -70.9, -49.5 78.92, -1.32 out-in-in SNCoii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.36, 153.22 APE9-dihe-na 140.63, -165.78 APE8-dihe-in -116.87, 110.95 APE8-rot-in 311.97 APE67-dihe-in -63.22, -18.39 -42.29, -46.59 APE12-dist-in 9.971 APE11-dist-in 11.837 APE10-dist-in 6.403 APE9-dist-in 3.904 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 B 323 275 20 0 0 5 [[183, 456]] 1.0 5uiq TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQC Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.99 14.088 BLAminus -129.3, 173.99 64.73, 91.59 -115.5, 16.73 307.85, 97.93 -64.38, -30.3 in-out in 8.785 Saltbr-out 4.402 HRD-in -65.88, -50.65 76.92, 0.42 out-in-in SNCoii in-in ActLoopNT-in 2.793 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.19, 152.87 APE9-dihe-na 139.13, -167.26 APE8-dihe-in -115.65, 111.65 APE8-rot-in 310.37 APE67-dihe-in -63.01, -19.88 -42.68, -46.48 APE12-dist-in 9.642 APE11-dist-in 11.831 APE10-dist-in 6.393 APE9-dist-in 3.9 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 C 323 283 12 0 0 4 [[183, 456]] 1.0 5uiq TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQD Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.959 14.266 BLAminus -119.1, 174.77 64.33, 95.9 -120.23, 16.26 309.43, 94.98 -65.41, -29.0 in-out in 8.631 Saltbr-out 4.261 HRD-in -57.37, -47.98 74.72, -2.81 out-in-in SNCoii in-in ActLoopNT-in 2.932 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.96, 150.91 APE9-dihe-na 138.88, -168.68 APE8-dihe-in -114.25, 111.41 APE8-rot-in 310.92 APE67-dihe-in -61.78, -19.41 -45.33, -46.22 APE12-dist-in 9.614 APE11-dist-in 11.792 APE10-dist-in 6.373 APE9-dist-in 3.99 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 D 323 274 21 0 0 6 [[183, 456]] 1.0 5uiq TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: 8BV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5UIQC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5UIQA Q9NWZ3 164 459 460.0 8BV:501 Type1 Inactive DFGin 6.931 14.309 BLAminus -127.76, 177.14 59.33, 95.8 -119.34, 15.89 308.77, 95.83 -65.11, -29.47 in-out in 8.65 Saltbr-out 4.302 HRD-in -67.28, -50.5 79.56, -0.59 out-in-in SNCoii in-in ActLoopNT-in 2.805 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.14, 152.7 APE9-dihe-na 138.15, -166.94 APE8-dihe-in -116.13, 111.27 APE8-rot-in 312.43 APE67-dihe-in -63.93, -18.01 -42.44, -46.16 APE12-dist-in 9.869 APE11-dist-in 11.872 APE10-dist-in 6.442 APE9-dist-in 3.93 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 A 323 271 25 0 0 4 [[183, 456]] 1.0 5uiq Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQB Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.804 14.376 BLAminus -130.56, -176.5 54.94, 94.68 -118.91, 16.72 307.57, 95.93 -64.01, -29.62 in-out in 8.829 Saltbr-out 4.386 HRD-in -70.9, -49.5 78.92, -1.32 out-in-in SNCoii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.36, 153.22 APE9-dihe-na 140.63, -165.78 APE8-dihe-in -116.87, 110.95 APE8-rot-in 311.97 APE67-dihe-in -63.22, -18.39 -42.29, -46.59 APE12-dist-in 9.971 APE11-dist-in 11.837 APE10-dist-in 6.403 APE9-dist-in 3.904 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 B 323 275 20 0 0 5 [[183, 456]] 1.0 5uiq Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQC Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.99 14.088 BLAminus -129.3, 173.99 64.73, 91.59 -115.5, 16.73 307.85, 97.93 -64.38, -30.3 in-out in 8.785 Saltbr-out 4.402 HRD-in -65.88, -50.65 76.92, 0.42 out-in-in SNCoii in-in ActLoopNT-in 2.793 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.19, 152.87 APE9-dihe-na 139.13, -167.26 APE8-dihe-in -115.65, 111.65 APE8-rot-in 310.37 APE67-dihe-in -63.01, -19.88 -42.68, -46.48 APE12-dist-in 9.642 APE11-dist-in 11.831 APE10-dist-in 6.393 APE9-dist-in 3.9 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 C 323 283 12 0 0 4 [[183, 456]] 1.0 5uiq Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQD Q9NWZ3 164 458 460.0 8BV:501 Type1 Inactive DFGin 6.959 14.266 BLAminus -119.1, 174.77 64.33, 95.9 -120.23, 16.26 309.43, 94.98 -65.41, -29.0 in-out in 8.631 Saltbr-out 4.261 HRD-in -57.37, -47.98 74.72, -2.81 out-in-in SNCoii in-in ActLoopNT-in 2.932 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.96, 150.91 APE9-dihe-na 138.88, -168.68 APE8-dihe-in -114.25, 111.41 APE8-rot-in 310.92 APE67-dihe-in -61.78, -19.41 -45.33, -46.22 APE12-dist-in 9.614 APE11-dist-in 11.792 APE10-dist-in 6.373 APE9-dist-in 3.99 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.64 0.199 0.226 D 323 274 21 0 0 6 [[183, 456]] 1.0 5uiq Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: 8BV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name