Ligand: 7KC

Total number of chains: 4
Active chains: 2
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4KS7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK MELK MELK_HUMAN 5MAGA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KC Type1 3 - 335 0 None None Maternal embryonic leucine zipper kinase
STE PAK1 PAK1_HUMAN 4O0RA 2.4 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK4 PAK4_HUMAN 2X4ZA 2.1 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 299 - 590 0 SEP474 P296G,Q297S,R298H,V299M Serine/threonine-protein kinase PAK 4
STE PAK6 PAK6_HUMAN 4KS7A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 386 - 672 0 SEP560 None Serine/threonine-protein kinase PAK 6

Ligand: 7KC

Total number of chains: 4
Active chains: 2
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4KS7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK MELK MELK_HUMAN 5MAGA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KC Type1 3 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
STE PAK1 PAK1_HUMAN 4O0RA 2.4 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK4 PAK4_HUMAN 2X4ZA 2.1 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 299 - 590 0 SEP474 P296G,Q297S,R298H,V299M Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK6 PAK6_HUMAN 4KS7A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 386 - 672 0 SEP560 None Serine/threonine-protein kinase PAK 6 Homo sapiens

Ligand: 7KC

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism