Ligand: 7A7

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5LXDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CLK1 CLK1_HUMAN 6YTIA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7A7 Type1 150 - 482 0 None None Dual specificity protein kinase CLK1
CMGC DYRK2 DYRK2_HUMAN 5LXDA 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7A7 Type1 153 - 538 0 PTR382 None Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN 5LXDB 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7A7 Type1 153 - 538 0 PTR382 None Dual specificity tyrosine-phosphorylation-regulated kinase 2

Ligand: 7A7

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5LXDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CLK1 CLK1_HUMAN 6YTIA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7A7 Type1 150 - 482 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC DYRK2 DYRK2_HUMAN 5LXDA 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7A7 Type1 153 - 538 0 PTR382 None Dual specificity tyrosine-phosphorylation-regulated kinase 2 Homo sapiens
CMGC DYRK2 DYRK2_HUMAN 5LXDB 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7A7 Type1 153 - 538 0 PTR382 None Dual specificity tyrosine-phosphorylation-regulated kinase 2 Homo sapiens

Ligand: 7A7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism