Ligand: 76P

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5T1TC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5T1TA Q9NWZ3 163 459 460.0 76P:9901 Type1 Inactive DFGin 6.887 13.956 BLAminus -133.7, 176.64 67.32, 81.1 -107.48, 15.55 308.96, 93.07 -63.8, -32.84 in-out in 8.856 Saltbr-out 4.692 HRD-in -67.26, -50.15 75.88, -1.73 out-in-in SNCoii in-in ActLoopNT-in 2.743 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.24, 158.51 APE9-dihe-na 129.02, -169.71 APE8-dihe-in -114.13, 114.14 APE8-rot-in 310.96 APE67-dihe-in -64.47, -17.8 -40.74, -50.47 APE12-dist-in 9.848 APE11-dist-in 11.755 APE10-dist-in 6.366 APE9-dist-in 3.88 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 A 301 286 11 0 0 6 [[183, 456]] 1.0 5t1t TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TB Q9NWZ3 161 459 460.0 76P:9901 Type1 Inactive DFGin 6.939 13.993 BLAminus -132.8, 176.38 67.63, 80.73 -108.02, 15.73 309.33, 93.37 -64.25, -32.84 in-out in 8.925 Saltbr-out 4.035 HRD-in -67.17, -50.18 76.11, -2.27 out-in-in SNCoii in-in ActLoopNT-in 2.741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.26, 158.14 APE9-dihe-na 129.32, -169.9 APE8-dihe-in -113.91, 113.67 APE8-rot-in 310.6 APE67-dihe-in -63.34, -18.99 -40.46, -50.32 APE12-dist-in 9.79 APE11-dist-in 11.762 APE10-dist-in 6.365 APE9-dist-in 3.878 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 B 301 283 16 0 0 5 [[183, 456]] 1.0 5t1t TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TC Q9NWZ3 164 460 460.0 76P:9901 Type1 Inactive DFGin 6.931 13.953 BLAminus -133.8, 176.71 66.9, 81.1 -106.8, 16.35 308.8, 92.24 -64.12, -32.99 in-out in 8.941 Saltbr-out 4.792 HRD-in -66.05, -49.3 74.35, -2.18 out-in-in SNCoii in-in ActLoopNT-in 2.738 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.21, 158.83 APE9-dihe-na 129.01, -170.01 APE8-dihe-in -113.41, 113.59 APE8-rot-in 310.43 APE67-dihe-in -64.34, -19.05 -39.55, -50.27 APE12-dist-in 9.735 APE11-dist-in 11.779 APE10-dist-in 6.376 APE9-dist-in 3.876 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 C 301 289 8 0 0 4 [[183, 456]] 1.0 5t1t TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TD Q9NWZ3 164 459 460.0 76P:9901 Type1 Inactive DFGin 6.969 13.999 BLAminus -132.86, 176.93 67.54, 80.5 -108.06, 15.43 309.35, 93.29 -64.49, -32.38 in-out in 9.075 Saltbr-out 4.29 HRD-in -67.54, -50.03 76.03, -1.74 out-in-in SNCoii in-in ActLoopNT-in 2.748 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.33, 157.65 APE9-dihe-na 129.81, -169.72 APE8-dihe-in -114.04, 113.72 APE8-rot-in 310.35 APE67-dihe-in -63.86, -17.96 -40.26, -50.55 APE12-dist-in 9.78 APE11-dist-in 11.755 APE10-dist-in 6.37 APE9-dist-in 3.897 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 D 301 286 10 0 0 5 [[183, 456]] 1.0 5t1t TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: 76P

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5T1TC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5T1TA Q9NWZ3 163 459 460.0 76P:9901 Type1 Inactive DFGin 6.887 13.956 BLAminus -133.7, 176.64 67.32, 81.1 -107.48, 15.55 308.96, 93.07 -63.8, -32.84 in-out in 8.856 Saltbr-out 4.692 HRD-in -67.26, -50.15 75.88, -1.73 out-in-in SNCoii in-in ActLoopNT-in 2.743 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.24, 158.51 APE9-dihe-na 129.02, -169.71 APE8-dihe-in -114.13, 114.14 APE8-rot-in 310.96 APE67-dihe-in -64.47, -17.8 -40.74, -50.47 APE12-dist-in 9.848 APE11-dist-in 11.755 APE10-dist-in 6.366 APE9-dist-in 3.88 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 A 301 286 11 0 0 6 [[183, 456]] 1.0 5t1t Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TB Q9NWZ3 161 459 460.0 76P:9901 Type1 Inactive DFGin 6.939 13.993 BLAminus -132.8, 176.38 67.63, 80.73 -108.02, 15.73 309.33, 93.37 -64.25, -32.84 in-out in 8.925 Saltbr-out 4.035 HRD-in -67.17, -50.18 76.11, -2.27 out-in-in SNCoii in-in ActLoopNT-in 2.741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.26, 158.14 APE9-dihe-na 129.32, -169.9 APE8-dihe-in -113.91, 113.67 APE8-rot-in 310.6 APE67-dihe-in -63.34, -18.99 -40.46, -50.32 APE12-dist-in 9.79 APE11-dist-in 11.762 APE10-dist-in 6.365 APE9-dist-in 3.878 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 B 301 283 16 0 0 5 [[183, 456]] 1.0 5t1t Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TC Q9NWZ3 164 460 460.0 76P:9901 Type1 Inactive DFGin 6.931 13.953 BLAminus -133.8, 176.71 66.9, 81.1 -106.8, 16.35 308.8, 92.24 -64.12, -32.99 in-out in 8.941 Saltbr-out 4.792 HRD-in -66.05, -49.3 74.35, -2.18 out-in-in SNCoii in-in ActLoopNT-in 2.738 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.21, 158.83 APE9-dihe-na 129.01, -170.01 APE8-dihe-in -113.41, 113.59 APE8-rot-in 310.43 APE67-dihe-in -64.34, -19.05 -39.55, -50.27 APE12-dist-in 9.735 APE11-dist-in 11.779 APE10-dist-in 6.376 APE9-dist-in 3.876 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 C 301 289 8 0 0 4 [[183, 456]] 1.0 5t1t Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TD Q9NWZ3 164 459 460.0 76P:9901 Type1 Inactive DFGin 6.969 13.999 BLAminus -132.86, 176.93 67.54, 80.5 -108.06, 15.43 309.35, 93.29 -64.49, -32.38 in-out in 9.075 Saltbr-out 4.29 HRD-in -67.54, -50.03 76.03, -1.74 out-in-in SNCoii in-in ActLoopNT-in 2.748 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.33, 157.65 APE9-dihe-na 129.81, -169.72 APE8-dihe-in -114.04, 113.72 APE8-rot-in 310.35 APE67-dihe-in -63.86, -17.96 -40.26, -50.55 APE12-dist-in 9.78 APE11-dist-in 11.755 APE10-dist-in 6.37 APE9-dist-in 3.897 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.34 0.207 0.228 D 301 286 10 0 0 5 [[183, 456]] 1.0 5t1t Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: 76P

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name