Ligand: 5CN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 2I1MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR CSF1R CSF1R_HUMAN 2I1MA P07333 547 921 972.0 5CN:61000 Type1 Inactive DFGout 12.3228 11.1859 BBAminus -165.19, 169.45 -79.56, 109.66 -111.25, 8.35 308.47, 136.96 -49.04, -52.97 in-out in 8.1192 Saltbr-out 3.6117 HRD-in -87.64, -57.31 78.72, -7.69 out-out-in SNCooi out-in ActLoopNT-out 15.5718 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -126.26, 115.95 APE9-dihe-in -121.8, 145.36 APE8-dihe-in -81.22, 65.36 APE8-rot-na 37.81 APE67-dihe-in -63.67, -16.66 -45.68, -43.82 APE12-dist-na 17.438 APE11-dist-na 14.1582 APE10-dist-na 12.2046 APE9-dist-in 7.505 None None None XRAY 1.8 0.25 0.282 A 333.0 311.0 7 30 30 0 [[582, 912]] 1.0 2i1m TYR_CSF1R_HUMAN TYR 1.9e-104 356.3 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0YA P07333 548 916 972.0 5CN:61000 Type1 Inactive DFGout 12.2816 11.3436 BBAminus -165.97, 175.75 -91.87, 106.47 -107.9, 6.58 310.92, 141.83 -49.48, -41.66 in-in in 7.9023 Saltbr-in 2.8473 HRD-in -90.07, -51.41 71.45, -1.27 in-out-in SNCioi out-in ActLoopNT-out 15.3689 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.69, 108.9 APE9-dihe-in -117.45, 142.95 APE8-dihe-in -79.32, 69.94 APE8-rot-na 34.17 APE67-dihe-in -65.64, -10.36 -48.82, -42.67 APE12-dist-na 999.0 APE11-dist-na 14.7786 APE10-dist-na 12.2545 APE9-dist-in 7.5694 None None None XRAY 1.9 0.246 0.263 A 335.0 289.0 17 30 29 1 [[582, 912]] 1.0 2i0y TYR_CSF1R_HUMAN TYR 2.5e-105 359.2 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor

Ligand: 5CN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 2I1MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR CSF1R CSF1R_HUMAN 2I1MA P07333 547 921 972.0 5CN:61000 Type1 Inactive DFGout 12.3228 11.1859 BBAminus -165.19, 169.45 -79.56, 109.66 -111.25, 8.35 308.47, 136.96 -49.04, -52.97 in-out in 8.1192 Saltbr-out 3.6117 HRD-in -87.64, -57.31 78.72, -7.69 out-out-in SNCooi out-in ActLoopNT-out 15.5718 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -126.26, 115.95 APE9-dihe-in -121.8, 145.36 APE8-dihe-in -81.22, 65.36 APE8-rot-na 37.81 APE67-dihe-in -63.67, -16.66 -45.68, -43.82 APE12-dist-na 17.438 APE11-dist-na 14.1582 APE10-dist-na 12.2046 APE9-dist-in 7.505 None None None XRAY 1.8 0.25 0.282 A 333.0 311.0 7 30 30 0 [[582, 912]] 1.0 2i1m Homo sapiens TYR_CSF1R_HUMAN TYR 1.9e-104 356.3 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0YA P07333 548 916 972.0 5CN:61000 Type1 Inactive DFGout 12.2816 11.3436 BBAminus -165.97, 175.75 -91.87, 106.47 -107.9, 6.58 310.92, 141.83 -49.48, -41.66 in-in in 7.9023 Saltbr-in 2.8473 HRD-in -90.07, -51.41 71.45, -1.27 in-out-in SNCioi out-in ActLoopNT-out 15.3689 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.69, 108.9 APE9-dihe-in -117.45, 142.95 APE8-dihe-in -79.32, 69.94 APE8-rot-na 34.17 APE67-dihe-in -65.64, -10.36 -48.82, -42.67 APE12-dist-na 999.0 APE11-dist-na 14.7786 APE10-dist-na 12.2545 APE9-dist-in 7.5694 None None None XRAY 1.9 0.246 0.263 A 335.0 289.0 17 30 29 1 [[582, 912]] 1.0 2i0y Homo sapiens TYR_CSF1R_HUMAN TYR 2.5e-105 359.2 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor

Ligand: 5CN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name