Ligand: 59T

Total number of chains: 5
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 60.0% 7B36A
DFGin BLAminus 1 20.0% 5DEYA
DFGin None 1 20.0% 5DEYB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE PAK1 PAK1_HUMAN 5DEYA Q13153 250 544 545.0 59T:601 Type1.5_Back Inactive DFGin 6.6004 16.1661 BLAminus -131.14, -174.85 50.94, 92.95 -106.38, 27.39 288.04, 68.31 -72.58, -10.67 out-out out 10.3982 Saltbr-out 5.8342 HRD-in -69.08, -50.91 69.33, -1.54 out-in-in SNCoii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.31, 128.21 APE9-dihe-na 145.37, -164.07 APE8-dihe-in -109.42, 124.2 APE8-rot-in 309.98 APE67-dihe-in -54.43, -26.29 -42.69, -59.37 APE12-dist-in 10.1661 APE11-dist-in 11.8261 APE10-dist-in 6.0856 APE9-dist-in 3.5747 D389N,T423E None None XRAY 2.1 0.186 0.228 A 297.0 295.0 0 28 28 0 [[270, 521]] 1.0 5dey STE_PAK1_HUMAN STE 3.3e-94 321.0 1.0 257.0 257.0 406 407 408 410 412 299 315 319 386 388 387 389.0 446 434 429 428 427 426 425 424 423 345 Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 5DEYB Q13153 255 542 545.0 59T:601 Type1 Inactive DFGin 7.3498 15.4583 None -123.29, 170.33 -82.44, 174.75 -121.32, 55.91 7.6, 122.84 -96.3, -43.82 out-out out 11.7695 Saltbr-out 9.8581 HRD-in -72.29, -49.87 79.14, -22.24 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oooo APE10-dihe-na -79.22, -70.08 APE9-dihe-na -89.37, 158.31 APE8-dihe-in -85.28, 117.06 APE8-rot-in 296.79 APE67-dihe-out -66.47, -20.46 -79.34, 69.72 APE12-dist-out 19.4815 APE11-dist-out 16.9726 APE10-dist-out 15.3171 APE9-dist-out 12.9671 D389N,T423E None None XRAY 2.1 0.186 0.228 B 297.0 281.0 7 28 21 7 [[270, 521]] 1.0 5dey STE_PAK1_HUMAN STE 3.3e-94 321.0 1.0 257.0 257.0 406 407 408 410 412 299 315 319 386 388 387 389.0 446 434 429 428 427 426 425 424 423 345 Serine/threonine-protein kinase PAK 1
STE STK24 STK24_HUMAN 7B30A Q9Y6E0 26 301 443.0 59T:60401 Type1.5_Front Inactive DFGin 5.9977 16.3415 BLBminus -142.66, 171.86 53.27, 62.4 -55.16, 145.73 286.02, 54.35 -77.45, 152.93 out-out out 10.1519 Saltbr-out 5.1549 HRD-in -71.84, -49.63 80.65, -3.71 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 136.97 APE8-rot-out 199.34 APE67-dihe-in -62.34, -30.7 -96.14, -7.31 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.178 0.196 A 306.0 259.0 17 28 13 15 [[36, 286]] 1.0 7b30 STE_STK24_HUMAN STE 3.7e-100 340.5 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24
STE STK26 STK26_HUMAN 7B36C Q9P289 17 299 416.0 59T:502 Type1.5_Back Inactive DFGin 6.1836 16.2685 BLBminus -154.18, 168.23 53.02, 70.41 -66.08, 149.17 285.3, 45.82 -70.53, 152.13 out-out out 10.4503 Saltbr-out 5.6717 HRD-in -65.22, -54.58 87.76, -9.0 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -169.33 APE9-dihe-na 95.0, -91.12 APE8-dihe-in -128.55, 97.01 APE8-rot-out 39.35 APE67-dihe-in -63.97, -27.56 -96.14, 11.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.011 APE9-dist-out 11.4271 None None None XRAY 2.107 0.203 0.244 C 301.0 267.0 16 28 15 13 [[24, 274]] 1.0 7b36 STE_STK26_HUMAN STE 3.5e-100 340.6 1.0 257.0 257.0 161 162 163 165 167 53 70 74 141 143 142 144.0 201 189 184 183 182 181 180 179 178 100 Serine/threonine-protein kinase 26
STE STK26 STK26_HUMAN 7B36A Q9P289 18 300 416.0 59T:703 Type1.5_Front Inactive DFGin 5.9182 16.4965 BLBminus -143.98, 170.7 56.84, 62.11 -60.85, 154.55 283.92, 44.19 -84.52, 163.38 out-out out 10.5287 Saltbr-out 5.4338 HRD-in -65.72, -54.18 91.14, -9.72 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -122.53 APE8-dihe-in -102.71, 115.66 APE8-rot-out 39.32 APE67-dihe-in -69.82, -27.39 -95.85, 15.56 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8351 None None None XRAY 2.107 0.203 0.244 A 301.0 268.0 15 28 14 14 [[24, 274]] 1.0 7b36 STE_STK26_HUMAN STE 3.5e-100 340.6 1.0 257.0 257.0 161 162 163 165 167 53 70 74 141 143 142 144.0 201 189 184 183 182 181 180 179 178 100 Serine/threonine-protein kinase 26

Ligand: 59T

Total number of chains: 5
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 60.0% 7B36A
DFGin BLAminus 1 20.0% 5DEYA
DFGin None 1 20.0% 5DEYB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE PAK1 PAK1_HUMAN 5DEYA Q13153 250 544 545.0 59T:601 Type1.5_Back Inactive DFGin 6.6004 16.1661 BLAminus -131.14, -174.85 50.94, 92.95 -106.38, 27.39 288.04, 68.31 -72.58, -10.67 out-out out 10.3982 Saltbr-out 5.8342 HRD-in -69.08, -50.91 69.33, -1.54 out-in-in SNCoii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.31, 128.21 APE9-dihe-na 145.37, -164.07 APE8-dihe-in -109.42, 124.2 APE8-rot-in 309.98 APE67-dihe-in -54.43, -26.29 -42.69, -59.37 APE12-dist-in 10.1661 APE11-dist-in 11.8261 APE10-dist-in 6.0856 APE9-dist-in 3.5747 D389N,T423E None None XRAY 2.1 0.186 0.228 A 297.0 295.0 0 28 28 0 [[270, 521]] 1.0 5dey Homo sapiens STE_PAK1_HUMAN STE 3.3e-94 321.0 1.0 257.0 257.0 406 407 408 410 412 299 315 319 386 388 387 389.0 446 434 429 428 427 426 425 424 423 345 Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 5DEYB Q13153 255 542 545.0 59T:601 Type1 Inactive DFGin 7.3498 15.4583 None -123.29, 170.33 -82.44, 174.75 -121.32, 55.91 7.6, 122.84 -96.3, -43.82 out-out out 11.7695 Saltbr-out 9.8581 HRD-in -72.29, -49.87 79.14, -22.24 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oooo APE10-dihe-na -79.22, -70.08 APE9-dihe-na -89.37, 158.31 APE8-dihe-in -85.28, 117.06 APE8-rot-in 296.79 APE67-dihe-out -66.47, -20.46 -79.34, 69.72 APE12-dist-out 19.4815 APE11-dist-out 16.9726 APE10-dist-out 15.3171 APE9-dist-out 12.9671 D389N,T423E None None XRAY 2.1 0.186 0.228 B 297.0 281.0 7 28 21 7 [[270, 521]] 1.0 5dey Homo sapiens STE_PAK1_HUMAN STE 3.3e-94 321.0 1.0 257.0 257.0 406 407 408 410 412 299 315 319 386 388 387 389.0 446 434 429 428 427 426 425 424 423 345 Serine/threonine-protein kinase PAK 1
STE STK24 STK24_HUMAN 7B30A Q9Y6E0 26 301 443.0 59T:60401 Type1.5_Front Inactive DFGin 5.9977 16.3415 BLBminus -142.66, 171.86 53.27, 62.4 -55.16, 145.73 286.02, 54.35 -77.45, 152.93 out-out out 10.1519 Saltbr-out 5.1549 HRD-in -71.84, -49.63 80.65, -3.71 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 136.97 APE8-rot-out 199.34 APE67-dihe-in -62.34, -30.7 -96.14, -7.31 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.178 0.196 A 306.0 259.0 17 28 13 15 [[36, 286]] 1.0 7b30 Homo sapiens STE_STK24_HUMAN STE 3.7e-100 340.5 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24
STE STK26 STK26_HUMAN 7B36C Q9P289 17 299 416.0 59T:502 Type1.5_Back Inactive DFGin 6.1836 16.2685 BLBminus -154.18, 168.23 53.02, 70.41 -66.08, 149.17 285.3, 45.82 -70.53, 152.13 out-out out 10.4503 Saltbr-out 5.6717 HRD-in -65.22, -54.58 87.76, -9.0 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -169.33 APE9-dihe-na 95.0, -91.12 APE8-dihe-in -128.55, 97.01 APE8-rot-out 39.35 APE67-dihe-in -63.97, -27.56 -96.14, 11.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.011 APE9-dist-out 11.4271 None None None XRAY 2.107 0.203 0.244 C 301.0 267.0 16 28 15 13 [[24, 274]] 1.0 7b36 Homo sapiens STE_STK26_HUMAN STE 3.5e-100 340.6 1.0 257.0 257.0 161 162 163 165 167 53 70 74 141 143 142 144.0 201 189 184 183 182 181 180 179 178 100 Serine/threonine-protein kinase 26
STE STK26 STK26_HUMAN 7B36A Q9P289 18 300 416.0 59T:703 Type1.5_Front Inactive DFGin 5.9182 16.4965 BLBminus -143.98, 170.7 56.84, 62.11 -60.85, 154.55 283.92, 44.19 -84.52, 163.38 out-out out 10.5287 Saltbr-out 5.4338 HRD-in -65.72, -54.18 91.14, -9.72 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -122.53 APE8-dihe-in -102.71, 115.66 APE8-rot-out 39.32 APE67-dihe-in -69.82, -27.39 -95.85, 15.56 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8351 None None None XRAY 2.107 0.203 0.244 A 301.0 268.0 15 28 14 14 [[24, 274]] 1.0 7b36 Homo sapiens STE_STK26_HUMAN STE 3.5e-100 340.6 1.0 257.0 257.0 161 162 163 165 167 53 70 74 141 143 142 144.0 201 189 184 183 182 181 180 179 178 100 Serine/threonine-protein kinase 26

Ligand: 59T

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name