Ligand: 573

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 4MNEA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 4MNEA Q02750 63 379 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.382 13.69 BLBplus -140.61, 176.72 54.72, 28.13 -81.46, 161.59 52.56, 86.0 -81.78, 73.09 out-out out 15.497 Saltbr-out 15.779 HRD-in -64.01, -56.53 90.31, -35.13 out-out-out SNCooo out-out ActLoopNT-out 9.29 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -73.66, 137.78 APE9-dihe-na -84.79, 178.97 APE8-dihe-out -113.02, -24.38 APE8-rot-out 49.94 APE67-dihe-out -153.46, 146.56 -142.39, -172.52 APE12-dist-out 17.192 APE11-dist-out 21.653 APE10-dist-out 23.798 APE9-dist-out 13.497 None None None XRAY 2.848 0.186 0.24 A 341 286 31 0 0 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNED Q02750 66 382 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.263 13.873 BLBplus -124.78, 174.1 56.33, 33.25 -88.39, 154.28 50.46, 89.74 -73.02, 74.09 out-out out 15.538 Saltbr-out 15.614 HRD-in -64.9, -49.38 74.62, -12.51 out-out-out SNCooo out-out ActLoopNT-out 9.043 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -65.65, 150.79 APE9-dihe-na -95.28, -163.25 APE8-dihe-out -122.75, -11.87 APE8-rot-out 68.42 APE67-dihe-out -159.06, 142.59 -161.08, -176.92 APE12-dist-out 17.403 APE11-dist-out 21.784 APE10-dist-out 23.852 APE9-dist-out 13.632 None None None XRAY 2.848 0.186 0.24 D 341 285 32 0 0 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEE Q02750 62 379 393.0 ACP:901,573:903 ATPlike,Type3 Inactive DFGin 6.301 13.741 BLBplus -139.17, 176.14 61.58, 40.21 -96.23, 153.1 47.97, 96.35 -69.87, 64.71 out-out out 15.796 Saltbr-out 16.157 HRD-in -84.17, -39.22 69.48, -27.4 out-out-out SNCooo out-out ActLoopNT-out 9.277 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -76.04, 124.0 APE9-dihe-na -78.04, -178.79 APE8-dihe-out -111.0, -36.1 APE8-rot-out 69.56 APE67-dihe-out -140.43, 146.63 -132.48, 167.21 APE12-dist-out 17.663 APE11-dist-out 21.775 APE10-dist-out 24.237 APE9-dist-out 13.553 None None None XRAY 2.848 0.186 0.24 E 341 286 32 0 0 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEH Q02750 66 380 393.0 ACP:901,573:903,573:904 ATPlike,Type3,Allosteric Inactive DFGin 6.378 13.891 BLBplus -149.03, 175.24 52.75, 36.33 -93.4, 157.98 53.98, 84.28 -78.54, 56.84 out-out out 15.815 Saltbr-out 15.456 HRD-in -72.48, -51.28 80.05, -1.12 out-out-out SNCooo out-out ActLoopNT-out 9.111 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.87, 146.83 APE9-dihe-na -98.86, 164.39 APE8-dihe-out -71.61, -59.39 APE8-rot-in 294.12 APE67-dihe-out -156.42, 156.79 -128.0, -169.25 APE12-dist-out 17.747 APE11-dist-out 21.888 APE10-dist-out 24.157 APE9-dist-out 13.665 None None None XRAY 2.848 0.186 0.24 H 341 275 40 0 0 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

Ligand: 573

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 4MNEA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 4MNEA Q02750 63 379 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.382 13.69 BLBplus -140.61, 176.72 54.72, 28.13 -81.46, 161.59 52.56, 86.0 -81.78, 73.09 out-out out 15.497 Saltbr-out 15.779 HRD-in -64.01, -56.53 90.31, -35.13 out-out-out SNCooo out-out ActLoopNT-out 9.29 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -73.66, 137.78 APE9-dihe-na -84.79, 178.97 APE8-dihe-out -113.02, -24.38 APE8-rot-out 49.94 APE67-dihe-out -153.46, 146.56 -142.39, -172.52 APE12-dist-out 17.192 APE11-dist-out 21.653 APE10-dist-out 23.798 APE9-dist-out 13.497 None None None XRAY 2.848 0.186 0.24 A 341 286 31 0 0 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNED Q02750 66 382 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.263 13.873 BLBplus -124.78, 174.1 56.33, 33.25 -88.39, 154.28 50.46, 89.74 -73.02, 74.09 out-out out 15.538 Saltbr-out 15.614 HRD-in -64.9, -49.38 74.62, -12.51 out-out-out SNCooo out-out ActLoopNT-out 9.043 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -65.65, 150.79 APE9-dihe-na -95.28, -163.25 APE8-dihe-out -122.75, -11.87 APE8-rot-out 68.42 APE67-dihe-out -159.06, 142.59 -161.08, -176.92 APE12-dist-out 17.403 APE11-dist-out 21.784 APE10-dist-out 23.852 APE9-dist-out 13.632 None None None XRAY 2.848 0.186 0.24 D 341 285 32 0 0 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEE Q02750 62 379 393.0 ACP:901,573:903 ATPlike,Type3 Inactive DFGin 6.301 13.741 BLBplus -139.17, 176.14 61.58, 40.21 -96.23, 153.1 47.97, 96.35 -69.87, 64.71 out-out out 15.796 Saltbr-out 16.157 HRD-in -84.17, -39.22 69.48, -27.4 out-out-out SNCooo out-out ActLoopNT-out 9.277 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -76.04, 124.0 APE9-dihe-na -78.04, -178.79 APE8-dihe-out -111.0, -36.1 APE8-rot-out 69.56 APE67-dihe-out -140.43, 146.63 -132.48, 167.21 APE12-dist-out 17.663 APE11-dist-out 21.775 APE10-dist-out 24.237 APE9-dist-out 13.553 None None None XRAY 2.848 0.186 0.24 E 341 286 32 0 0 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEH Q02750 66 380 393.0 ACP:901,573:903,573:904 ATPlike,Type3,Allosteric Inactive DFGin 6.378 13.891 BLBplus -149.03, 175.24 52.75, 36.33 -93.4, 157.98 53.98, 84.28 -78.54, 56.84 out-out out 15.815 Saltbr-out 15.456 HRD-in -72.48, -51.28 80.05, -1.12 out-out-out SNCooo out-out ActLoopNT-out 9.111 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.87, 146.83 APE9-dihe-na -98.86, 164.39 APE8-dihe-out -71.61, -59.39 APE8-rot-in 294.12 APE67-dihe-out -156.42, 156.79 -128.0, -169.25 APE12-dist-out 17.747 APE11-dist-out 21.888 APE10-dist-out 24.157 APE9-dist-out 13.665 None None None XRAY 2.848 0.186 0.24 H 341 275 40 0 0 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

Ligand: 573

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name