Ligand: 4KT

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5AX9A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE TNIK TNIK_HUMAN 5AX9A 2.4 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 4KT Type1 12 - 307 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5AX9B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 4KT Type1 13 - 307 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5AX9C 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno 4KT Type1 12 - 309 0 None None TRAF2 and NCK-interacting protein kinase

Ligand: 4KT

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5AX9A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE TNIK TNIK_HUMAN 5AX9A 2.4 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 4KT Type1 12 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5AX9B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 4KT Type1 13 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5AX9C 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno 4KT Type1 12 - 309 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens

Ligand: 4KT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism