Ligand: 4F2

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4Y46A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK10 MK10_HUMAN 4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10

Ligand: 4F2

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4Y46A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK10 MK10_HUMAN 4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens

Ligand: 4F2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism