Ligand: 4B7

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 100.0% 4YC8B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ABL1 ABL1_HUMAN 4YC8A P00519 233 501 1130.0 4B7:601 Type1.5_Front Inactive DFGinter 9.2536 9.4795 None -68.71, 128.66 -122.3, 46.03 -98.31, 2.86 321.16, 121.85 -137.07, 20.9 out-none out 11.1416 Saltbr-none 999.0 HRD-in -85.64, -50.32 70.16, -2.63 none-out-in SNCnoi out-in ActLoopNT-out 5.4398 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.08, 143.55 APE9-dihe-in -125.76, 160.26 APE8-dihe-in -76.74, 87.45 APE8-rot-na 25.75 APE67-dihe-in -57.03, -17.99 -35.8, -54.26 APE12-dist-na 19.1265 APE11-dist-na 14.4499 APE10-dist-na 17.471 APE9-dist-in 6.7471 None None None XRAY 2.9 0.199 0.24 A 287.0 259.0 10 29 29 0 [[242, 495]] 1.0 4yc8 TYR_ABL1_HUMAN TYR 2.7e-100 340.9 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4YC8B P00519 233 502 1130.0 4B7:601 Type1.5_Front Inactive DFGinter 9.5551 9.6924 None -74.12, 129.26 -121.25, 39.81 -90.85, -3.87 317.47, 128.16 -153.9, 45.6 out-none out 10.8223 Saltbr-none 999.0 HRD-in -86.46, -51.93 71.35, -5.5 none-out-in SNCnoi out-in ActLoopNT-out 5.4443 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -108.97, 118.68 APE9-dihe-in -109.17, 158.88 APE8-dihe-in -76.82, 85.24 APE8-rot-na 25.02 APE67-dihe-in -65.91, -22.69 -34.29, -47.11 APE12-dist-na 19.6692 APE11-dist-na 14.9891 APE10-dist-na 17.7851 APE9-dist-in 6.9304 None None None XRAY 2.9 0.199 0.24 B 287.0 264.0 6 29 29 0 [[242, 495]] 1.0 4yc8 TYR_ABL1_HUMAN TYR 2.7e-100 340.9 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1

Ligand: 4B7

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 66.7% 4YC8B
DFGin BLBplus 1 33.3% 4YBKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SRC SRC_CHICK 4YBKA P00523 256 533 533.0 4B7:601 Type1.5_Back Inactive DFGin 5.8568 13.189 BLBplus -125.89, 166.11 58.16, 34.31 -67.76, 127.28 26.86, 91.57 67.78, 14.93 out-out out 14.4117 Saltbr-out 14.8097 HRD-in -79.52, -57.44 87.24, -18.47 out-out-out SNCooo out-out ActLoopNT-out 8.1095 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 4.56 APE9-dihe-in -51.27, 125.48 APE8-dihe-in -80.21, 76.77 APE8-rot-na 28.79 APE67-dihe-in -60.89, -27.26 -55.62, -42.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.2276 APE9-dist-out 8.5837 None None None XRAY 2.5 0.208 0.252 A 286.0 266.0 12 29 17 12 [[267, 518]] 1.0 4ybk Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src
TYR ABL1 ABL1_HUMAN 4YC8A P00519 233 501 1130.0 4B7:601 Type1.5_Front Inactive DFGinter 9.2536 9.4795 None -68.71, 128.66 -122.3, 46.03 -98.31, 2.86 321.16, 121.85 -137.07, 20.9 out-none out 11.1416 Saltbr-none 999.0 HRD-in -85.64, -50.32 70.16, -2.63 none-out-in SNCnoi out-in ActLoopNT-out 5.4398 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.08, 143.55 APE9-dihe-in -125.76, 160.26 APE8-dihe-in -76.74, 87.45 APE8-rot-na 25.75 APE67-dihe-in -57.03, -17.99 -35.8, -54.26 APE12-dist-na 19.1265 APE11-dist-na 14.4499 APE10-dist-na 17.471 APE9-dist-in 6.7471 None None None XRAY 2.9 0.199 0.24 A 287.0 259.0 10 29 29 0 [[242, 495]] 1.0 4yc8 Homo sapiens TYR_ABL1_HUMAN TYR 2.7e-100 340.9 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4YC8B P00519 233 502 1130.0 4B7:601 Type1.5_Front Inactive DFGinter 9.5551 9.6924 None -74.12, 129.26 -121.25, 39.81 -90.85, -3.87 317.47, 128.16 -153.9, 45.6 out-none out 10.8223 Saltbr-none 999.0 HRD-in -86.46, -51.93 71.35, -5.5 none-out-in SNCnoi out-in ActLoopNT-out 5.4443 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -108.97, 118.68 APE9-dihe-in -109.17, 158.88 APE8-dihe-in -76.82, 85.24 APE8-rot-na 25.02 APE67-dihe-in -65.91, -22.69 -34.29, -47.11 APE12-dist-na 19.6692 APE11-dist-na 14.9891 APE10-dist-na 17.7851 APE9-dist-in 6.9304 None None None XRAY 2.9 0.199 0.24 B 287.0 264.0 6 29 29 0 [[242, 495]] 1.0 4yc8 Homo sapiens TYR_ABL1_HUMAN TYR 2.7e-100 340.9 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1

Ligand: 4B7

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 4YBKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR SRC SRC_CHICK 4YBKA P00523 256 533 533.0 4B7:601 Type1.5_Back Inactive DFGin 5.8568 13.189 BLBplus -125.89, 166.11 58.16, 34.31 -67.76, 127.28 26.86, 91.57 67.78, 14.93 out-out out 14.4117 Saltbr-out 14.8097 HRD-in -79.52, -57.44 87.24, -18.47 out-out-out SNCooo out-out ActLoopNT-out 8.1095 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 4.56 APE9-dihe-in -51.27, 125.48 APE8-dihe-in -80.21, 76.77 APE8-rot-na 28.79 APE67-dihe-in -60.89, -27.26 -55.62, -42.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.2276 APE9-dist-out 8.5837 None None None XRAY 2.5 0.208 0.252 A 286.0 266.0 12 29 17 12 [[267, 518]] 1.0 4ybk Gallus gallus TYR_SRC_CHICK TYR 3.4e-94 320.9 1.0 260.0 260.0 403 404 405 407 409 295 310 314 383 385 384 386.0 444 432 427 426 425 424 423 422 421 339 Proto-oncogene tyrosine-protein kinase Src