Ligand: 453

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: 453

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4WNKA
DFGin BLAminus 1 50.0% 5HE0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC GRK2 ARBK1_BOVIN 5HE0A P21146 30 668 689.0 453:701 Type1 Active DFGin 5.2592 13.1171 BLAminus -137.72, 161.16 67.72, 86.34 -84.98, 14.88 287.85, 80.12 -42.13, -60.12 in-in in 8.4671 Saltbr-in 2.8678 HRD-in -68.65, -49.34 77.87, -29.18 in-in-in SNCiii in-in ActLoopNT-in 2.8588 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.25, 120.14 APE9-dihe-na 171.2, -142.82 APE8-dihe-in -122.87, 132.42 APE8-rot-in 285.63 APE67-dihe-inflip 113.92, -33.46 -57.37, 128.9 APE12-dist-in 10.1735 APE11-dist-in 11.7707 APE10-dist-in 5.8798 APE9-dist-in 3.5488 S670A None None XRAY 2.56 0.205 0.264 A 641.0 621.0 0 26 26 0 [[191, 453]] 1.0 5he0 Bos taurus AGC_GRK2_BOVIN AGC 5.3e-77 268.8 1.0 260.0 260.0 334 335 336 338 340 220 239 243 314 316 315 317.0 373 360 355 354 353 352 351 350 349 272 Beta-adrenergic receptor kinase 1
AGC GRK5 GRK5_BOVIN 4WNKA P43249 24 541 590.0 453:60701 Type1.5_Front Inactive DFGin 6.2666 12.7972 ABAminus -122.04, -4.62 -137.77, 133.15 -132.09, 26.08 277.95, 69.95 -56.52, -33.29 in-in in 8.4843 Saltbr-in 2.7813 HRD-in -75.83, -57.19 76.27, -3.2 in-in-in SNCiii in-in ActLoopNT-in 3.0303 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.86, 160.08 APE9-dihe-na 138.36, -161.11 APE8-dihe-in -117.24, 138.85 APE8-rot-in 306.21 APE67-dihe-inflip 84.72, -13.63 -52.7, 138.28 APE12-dist-in 10.076 APE11-dist-in 11.9507 APE10-dist-in 6.1011 APE9-dist-in 3.9199 None None None XRAY 2.42 0.196 0.243 A 598.0 499.0 0 27 27 0 [[186, 448]] 1.0 4wnk Bos taurus AGC_GRK5_BOVIN AGC 2.2e-84 288.8 1.0 260.0 260.0 328 329 330 332 334 215 234 238 308 310 309 311.0 367 355 350 349 348 347 346 345 344 264 G protein-coupled receptor kinase 5

Ligand: 453

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4WNKA
DFGin BLAminus 1 50.0% 5HE0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC GRK2 ARBK1_BOVIN 5HE0A P21146 30 668 689.0 453:701 Type1 Active DFGin 5.2592 13.1171 BLAminus -137.72, 161.16 67.72, 86.34 -84.98, 14.88 287.85, 80.12 -42.13, -60.12 in-in in 8.4671 Saltbr-in 2.8678 HRD-in -68.65, -49.34 77.87, -29.18 in-in-in SNCiii in-in ActLoopNT-in 2.8588 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.25, 120.14 APE9-dihe-na 171.2, -142.82 APE8-dihe-in -122.87, 132.42 APE8-rot-in 285.63 APE67-dihe-inflip 113.92, -33.46 -57.37, 128.9 APE12-dist-in 10.1735 APE11-dist-in 11.7707 APE10-dist-in 5.8798 APE9-dist-in 3.5488 S670A None None XRAY 2.56 0.205 0.264 A 641.0 621.0 0 26 26 0 [[191, 453]] 1.0 5he0 Bos taurus AGC_GRK2_BOVIN AGC 5.3e-77 268.8 1.0 260.0 260.0 334 335 336 338 340 220 239 243 314 316 315 317.0 373 360 355 354 353 352 351 350 349 272 Beta-adrenergic receptor kinase 1
AGC GRK5 GRK5_BOVIN 4WNKA P43249 24 541 590.0 453:60701 Type1.5_Front Inactive DFGin 6.2666 12.7972 ABAminus -122.04, -4.62 -137.77, 133.15 -132.09, 26.08 277.95, 69.95 -56.52, -33.29 in-in in 8.4843 Saltbr-in 2.7813 HRD-in -75.83, -57.19 76.27, -3.2 in-in-in SNCiii in-in ActLoopNT-in 3.0303 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.86, 160.08 APE9-dihe-na 138.36, -161.11 APE8-dihe-in -117.24, 138.85 APE8-rot-in 306.21 APE67-dihe-inflip 84.72, -13.63 -52.7, 138.28 APE12-dist-in 10.076 APE11-dist-in 11.9507 APE10-dist-in 6.1011 APE9-dist-in 3.9199 None None None XRAY 2.42 0.196 0.243 A 598.0 499.0 0 27 27 0 [[186, 448]] 1.0 4wnk Bos taurus AGC_GRK5_BOVIN AGC 2.2e-84 288.8 1.0 260.0 260.0 328 329 330 332 334 215 234 238 308 310 309 311.0 367 355 350 349 348 347 346 345 344 264 G protein-coupled receptor kinase 5