Ligand: 42J

Total number of chains: 6
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 7AT9A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7AT5A P68400 2 333 391.0 RXE:402,42J:403 Type1,Allosteric Inactive DFGin 7.448 16.505 BLAminus -117.22, -174.52 49.86, 79.86 -94.37, 19.51 296.2, 81.09 -72.06, -16.58 in-in in 9.68 Saltbr-in 2.812 HRD-in -73.02, -48.87 70.0, 9.61 in-in-out SNCiio in-out ActLoopNT-in 2.85 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.97, 164.49 APE9-dihe-na 68.17, 159.13 APE8-dihe-in -70.98, 148.16 APE8-rot-out 155.52 APE67-dihe-in -68.14, -14.4 -47.42, -49.83 APE12-dist-in 12.721 APE11-dist-in 10.761 APE10-dist-in 6.24 APE9-dist-in 3.571 None None None XRAY 1.77 0.174 0.195 A 349 332 0 0 0 0 [[39, 324]] 1.0 7at5 CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7AT5B P68400 2 332 391.0 RXE:405,42J:406 Type1,Allosteric Inactive DFGin 7.471 16.225 BLAminus -116.23, -175.08 49.51, 81.31 -93.64, 19.87 296.83, 80.98 -71.53, -18.2 in-in in 9.428 Saltbr-in 2.687 HRD-in -73.49, -48.97 69.03, 9.59 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.35, 167.38 APE9-dihe-na 66.81, 158.37 APE8-dihe-in -73.11, 146.19 APE8-rot-out 156.74 APE67-dihe-in -66.51, -16.32 -46.85, -47.53 APE12-dist-in 12.56 APE11-dist-in 10.384 APE10-dist-in 6.132 APE9-dist-in 3.285 None None None XRAY 1.77 0.174 0.195 B 349 331 0 0 0 0 [[39, 324]] 1.0 7at5 CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CLPB P68400 3 329 391.0 42J:401,42J:402,42J:403,42J:404,42J:405 Type1,Allosteric,Allosteric,Allosteric,Allosteric Active DFGin 7.48 16.221 BLAminus -116.02, -178.48 54.67, 78.83 -94.44, 19.11 293.46, 80.37 -63.59, -25.38 in-in in 9.366 Saltbr-in 2.697 HRD-in -71.23, -47.36 65.59, 12.68 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.31, 169.5 APE9-dihe-na 62.46, 162.24 APE8-dihe-in -84.92, 146.81 APE8-rot-in 302.92 APE67-dihe-in -67.11, -16.33 -37.65, -53.85 APE12-dist-in 12.606 APE11-dist-in 10.386 APE10-dist-in 6.109 APE9-dist-in 3.146 R21S None None XRAY 1.684 0.178 0.193 B 352 327 0 0 0 0 [[39, 324]] 1.0 5clp CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CLPA P68400 3 329 391.0 42J:401,42J:402,42J:403,42J:404,42J:405,42J:406 Type1,Type1,Allosteric,Allosteric,Allosteric,Allosteric Active DFGin 7.426 16.382 BLAminus -114.93, -178.91 53.65, 78.95 -92.44, 19.32 294.77, 79.33 -66.03, -23.46 in-in in 9.538 Saltbr-in 2.746 HRD-in -71.64, -46.59 66.15, 11.79 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.71, 168.76 APE9-dihe-na 65.27, 162.05 APE8-dihe-in -84.76, 144.62 APE8-rot-in 302.56 APE67-dihe-in -67.06, -16.59 -35.05, -54.37 APE12-dist-in 12.616 APE11-dist-in 10.386 APE10-dist-in 6.097 APE9-dist-in 3.125 R21S None None XRAY 1.684 0.178 0.193 A 352 322 5 0 0 0 [[39, 324]] 1.0 5clp CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QBUA P19784 6 333 350.0 42J:404,3NG:405 Allosteric,Type1 Inactive DFGin 7.481 16.117 BLAminus -115.34, 177.54 56.37, 76.99 -87.29, 16.84 296.65, 81.34 -70.83, -16.25 in-in in 9.243 Saltbr-in 2.767 HRD-in -74.29, -50.68 73.5, 10.15 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.98, 166.78 APE9-dihe-na 65.99, 156.92 APE8-dihe-in -70.01, 146.12 APE8-rot-out 159.04 APE67-dihe-in -73.31, -10.45 -44.42, -45.9 APE12-dist-in 12.462 APE11-dist-in 10.009 APE10-dist-in 6.107 APE9-dist-in 3.241 C336S None None XRAY 1.09 0.16 0.179 A 364 328 0 0 0 0 [[40, 325]] 1.0 8qbu CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 42J

Total number of chains: 6
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 7AT9A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7AT5A P68400 2 333 391.0 RXE:402,42J:403 Type1,Allosteric Inactive DFGin 7.448 16.505 BLAminus -117.22, -174.52 49.86, 79.86 -94.37, 19.51 296.2, 81.09 -72.06, -16.58 in-in in 9.68 Saltbr-in 2.812 HRD-in -73.02, -48.87 70.0, 9.61 in-in-out SNCiio in-out ActLoopNT-in 2.85 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.97, 164.49 APE9-dihe-na 68.17, 159.13 APE8-dihe-in -70.98, 148.16 APE8-rot-out 155.52 APE67-dihe-in -68.14, -14.4 -47.42, -49.83 APE12-dist-in 12.721 APE11-dist-in 10.761 APE10-dist-in 6.24 APE9-dist-in 3.571 None None None XRAY 1.77 0.174 0.195 A 349 332 0 0 0 0 [[39, 324]] 1.0 7at5 Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7AT5B P68400 2 332 391.0 RXE:405,42J:406 Type1,Allosteric Inactive DFGin 7.471 16.225 BLAminus -116.23, -175.08 49.51, 81.31 -93.64, 19.87 296.83, 80.98 -71.53, -18.2 in-in in 9.428 Saltbr-in 2.687 HRD-in -73.49, -48.97 69.03, 9.59 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.35, 167.38 APE9-dihe-na 66.81, 158.37 APE8-dihe-in -73.11, 146.19 APE8-rot-out 156.74 APE67-dihe-in -66.51, -16.32 -46.85, -47.53 APE12-dist-in 12.56 APE11-dist-in 10.384 APE10-dist-in 6.132 APE9-dist-in 3.285 None None None XRAY 1.77 0.174 0.195 B 349 331 0 0 0 0 [[39, 324]] 1.0 7at5 Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CLPB P68400 3 329 391.0 42J:401,42J:402,42J:403,42J:404,42J:405 Type1,Allosteric,Allosteric,Allosteric,Allosteric Active DFGin 7.48 16.221 BLAminus -116.02, -178.48 54.67, 78.83 -94.44, 19.11 293.46, 80.37 -63.59, -25.38 in-in in 9.366 Saltbr-in 2.697 HRD-in -71.23, -47.36 65.59, 12.68 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.31, 169.5 APE9-dihe-na 62.46, 162.24 APE8-dihe-in -84.92, 146.81 APE8-rot-in 302.92 APE67-dihe-in -67.11, -16.33 -37.65, -53.85 APE12-dist-in 12.606 APE11-dist-in 10.386 APE10-dist-in 6.109 APE9-dist-in 3.146 R21S None None XRAY 1.684 0.178 0.193 B 352 327 0 0 0 0 [[39, 324]] 1.0 5clp Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CLPA P68400 3 329 391.0 42J:401,42J:402,42J:403,42J:404,42J:405,42J:406 Type1,Type1,Allosteric,Allosteric,Allosteric,Allosteric Active DFGin 7.426 16.382 BLAminus -114.93, -178.91 53.65, 78.95 -92.44, 19.32 294.77, 79.33 -66.03, -23.46 in-in in 9.538 Saltbr-in 2.746 HRD-in -71.64, -46.59 66.15, 11.79 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.71, 168.76 APE9-dihe-na 65.27, 162.05 APE8-dihe-in -84.76, 144.62 APE8-rot-in 302.56 APE67-dihe-in -67.06, -16.59 -35.05, -54.37 APE12-dist-in 12.616 APE11-dist-in 10.386 APE10-dist-in 6.097 APE9-dist-in 3.125 R21S None None XRAY 1.684 0.178 0.193 A 352 322 5 0 0 0 [[39, 324]] 1.0 5clp Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QBUA P19784 6 333 350.0 42J:404,3NG:405 Allosteric,Type1 Inactive DFGin 7.481 16.117 BLAminus -115.34, 177.54 56.37, 76.99 -87.29, 16.84 296.65, 81.34 -70.83, -16.25 in-in in 9.243 Saltbr-in 2.767 HRD-in -74.29, -50.68 73.5, 10.15 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.98, 166.78 APE9-dihe-na 65.99, 156.92 APE8-dihe-in -70.01, 146.12 APE8-rot-out 159.04 APE67-dihe-in -73.31, -10.45 -44.42, -45.9 APE12-dist-in 12.462 APE11-dist-in 10.009 APE10-dist-in 6.107 APE9-dist-in 3.241 C336S None None XRAY 1.09 0.16 0.179 A 364 328 0 0 0 0 [[40, 325]] 1.0 8qbu Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 42J

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name