Ligand: 34W

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QASA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER ULK1 ULK1_HUMAN 6QASA O75385 8 281 1050.0 34W:318 Type1 Inactive DFGin 6.7301 14.82 BLAminus -123.63, 171.57 69.53, 75.17 -96.26, 16.89 281.93, 76.2 -68.0, -21.45 in-in in 7.582 Saltbr-in 2.6735 HRD-in -81.87, -55.38 77.89, 3.62 in-in-out SNCiio in-out ActLoopNT-in 2.8491 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.04, 151.58 APE9-dihe-na 104.88, -171.7 APE8-dihe-in -104.31, 123.2 APE8-rot-out 183.78 APE67-dihe-in -70.87, -16.9 -48.83, -38.25 APE12-dist-in 8.0317 APE11-dist-in 10.8005 APE10-dist-in 5.6187 APE9-dist-in 3.3013 None SEP87,TPO180 SEP87,TPO180 XRAY 1.75 0.171 0.197 A 287.0 274.0 0 27 27 0 [[14, 278]] 1.0 6qas OTHER_ULK1_HUMAN ULK 2.1e-132 446.2 1.0 256.0 256.0 164 165 166 168 170 46 63 67 135 137 136 138.0 203 191 186 185 184 183 182 181 180 93 Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 6QASB O75385 8 280 1050.0 34W:315,34W:316 Type1,Allosteric Inactive DFGin 6.7751 14.8256 BLAminus -126.72, 176.42 67.25, 75.49 -100.21, 16.56 281.95, 78.82 -63.24, -25.02 in-in in 7.5824 Saltbr-in 2.7395 HRD-in -79.7, -52.04 77.45, 0.99 in-in-out SNCiio in-out ActLoopNT-in 2.8749 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.43, 147.7 APE9-dihe-na 105.19, -164.06 APE8-dihe-in -107.12, 129.65 APE8-rot-out 181.42 APE67-dihe-in -73.23, -12.27 -46.71, -45.1 APE12-dist-in 8.2185 APE11-dist-in 10.7161 APE10-dist-in 5.5666 APE9-dist-in 3.3156 None SEP87,TPO180 SEP87,TPO180 XRAY 1.75 0.171 0.197 B 287.0 273.0 0 27 27 0 [[14, 278]] 1.0 6qas OTHER_ULK1_HUMAN ULK 2.1e-132 446.2 1.0 256.0 256.0 164 165 166 168 170 46 63 67 135 137 136 138.0 203 191 186 185 184 183 182 181 180 93 Serine/threonine-protein kinase ULK1
OTHER WEE1 WEE1_HUMAN 5VD2A P30291 293 569 646.0 34W:601 Type1 Inactive DFGin 5.9933 13.8063 BLAminus -118.11, -175.73 48.54, 80.15 -89.98, 23.36 303.91, 15.2 -66.61, -20.92 out-out out 10.1031 Saltbr-out 5.226 HRD-in -86.76, -48.82 73.4, 11.77 out-in-out SNCoio in-out ActLoopNT-in 2.9547 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -58.71, 139.12 APE9-dihe-na -81.5, -178.72 APE8-dihe-in -42.43, 125.68 APE8-rot-na 195.33 APE67-dihe-in -69.68, -23.11 -63.52, -20.81 APE12-dist-in 8.3325 APE11-dist-out 5.4341 APE10-dist-out 9.4092 APE9-dist-in 3.596 None None None XRAY 2.05 0.206 0.256 A 289.0 258.0 19 24 24 0 [[299, 569]] 1.0 5vd2 OTHER_WEE1_HUMAN OTHER 1.4e-37 135.5 1.0 258.0 258.0 462 463 464 466 468 328 346 350 423 425 424 426.0 499 486 481 480 479 478 477 476 475 377 Wee1-like protein kinase
STE STK24 STK24_HUMAN 4QMVA Q9Y6E0 19 310 443.0 34W:60401 Type1 Active DFGin 6.4771 15.1714 BLAminus -132.65, 169.15 64.19, 83.52 -96.22, 28.1 288.71, 74.71 -49.26, -35.75 in-in in 9.2918 Saltbr-in 2.6846 HRD-in -73.82, -54.46 74.19, -0.93 in-in-in SNCiii in-in ActLoopNT-in 2.7165 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.04, 159.38 APE9-dihe-na 129.37, -165.47 APE8-dihe-in -112.52, 116.73 APE8-rot-in 308.46 APE67-dihe-in -58.8, -29.44 -30.13, -57.34 APE12-dist-in 8.5144 APE11-dist-in 10.8334 APE10-dist-in 5.0923 APE9-dist-in 3.2931 None TPO190 TPO190 XRAY 2.4 0.167 0.226 A 310.0 289.0 0 28 28 0 [[36, 286]] 1.0 4qmv STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24

Ligand: 34W

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QASA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER ULK1 ULK1_HUMAN 6QASA O75385 8 281 1050.0 34W:318 Type1 Inactive DFGin 6.7301 14.82 BLAminus -123.63, 171.57 69.53, 75.17 -96.26, 16.89 281.93, 76.2 -68.0, -21.45 in-in in 7.582 Saltbr-in 2.6735 HRD-in -81.87, -55.38 77.89, 3.62 in-in-out SNCiio in-out ActLoopNT-in 2.8491 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.04, 151.58 APE9-dihe-na 104.88, -171.7 APE8-dihe-in -104.31, 123.2 APE8-rot-out 183.78 APE67-dihe-in -70.87, -16.9 -48.83, -38.25 APE12-dist-in 8.0317 APE11-dist-in 10.8005 APE10-dist-in 5.6187 APE9-dist-in 3.3013 None SEP87,TPO180 SEP87,TPO180 XRAY 1.75 0.171 0.197 A 287.0 274.0 0 27 27 0 [[14, 278]] 1.0 6qas Homo sapiens OTHER_ULK1_HUMAN ULK 2.1e-132 446.2 1.0 256.0 256.0 164 165 166 168 170 46 63 67 135 137 136 138.0 203 191 186 185 184 183 182 181 180 93 Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 6QASB O75385 8 280 1050.0 34W:315,34W:316 Type1,Allosteric Inactive DFGin 6.7751 14.8256 BLAminus -126.72, 176.42 67.25, 75.49 -100.21, 16.56 281.95, 78.82 -63.24, -25.02 in-in in 7.5824 Saltbr-in 2.7395 HRD-in -79.7, -52.04 77.45, 0.99 in-in-out SNCiio in-out ActLoopNT-in 2.8749 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.43, 147.7 APE9-dihe-na 105.19, -164.06 APE8-dihe-in -107.12, 129.65 APE8-rot-out 181.42 APE67-dihe-in -73.23, -12.27 -46.71, -45.1 APE12-dist-in 8.2185 APE11-dist-in 10.7161 APE10-dist-in 5.5666 APE9-dist-in 3.3156 None SEP87,TPO180 SEP87,TPO180 XRAY 1.75 0.171 0.197 B 287.0 273.0 0 27 27 0 [[14, 278]] 1.0 6qas Homo sapiens OTHER_ULK1_HUMAN ULK 2.1e-132 446.2 1.0 256.0 256.0 164 165 166 168 170 46 63 67 135 137 136 138.0 203 191 186 185 184 183 182 181 180 93 Serine/threonine-protein kinase ULK1
OTHER WEE1 WEE1_HUMAN 5VD2A P30291 293 569 646.0 34W:601 Type1 Inactive DFGin 5.9933 13.8063 BLAminus -118.11, -175.73 48.54, 80.15 -89.98, 23.36 303.91, 15.2 -66.61, -20.92 out-out out 10.1031 Saltbr-out 5.226 HRD-in -86.76, -48.82 73.4, 11.77 out-in-out SNCoio in-out ActLoopNT-in 2.9547 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -58.71, 139.12 APE9-dihe-na -81.5, -178.72 APE8-dihe-in -42.43, 125.68 APE8-rot-na 195.33 APE67-dihe-in -69.68, -23.11 -63.52, -20.81 APE12-dist-in 8.3325 APE11-dist-out 5.4341 APE10-dist-out 9.4092 APE9-dist-in 3.596 None None None XRAY 2.05 0.206 0.256 A 289.0 258.0 19 24 24 0 [[299, 569]] 1.0 5vd2 Homo sapiens OTHER_WEE1_HUMAN OTHER 1.4e-37 135.5 1.0 258.0 258.0 462 463 464 466 468 328 346 350 423 425 424 426.0 499 486 481 480 479 478 477 476 475 377 Wee1-like protein kinase
STE STK24 STK24_HUMAN 4QMVA Q9Y6E0 19 310 443.0 34W:60401 Type1 Active DFGin 6.4771 15.1714 BLAminus -132.65, 169.15 64.19, 83.52 -96.22, 28.1 288.71, 74.71 -49.26, -35.75 in-in in 9.2918 Saltbr-in 2.6846 HRD-in -73.82, -54.46 74.19, -0.93 in-in-in SNCiii in-in ActLoopNT-in 2.7165 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.04, 159.38 APE9-dihe-na 129.37, -165.47 APE8-dihe-in -112.52, 116.73 APE8-rot-in 308.46 APE67-dihe-in -58.8, -29.44 -30.13, -57.34 APE12-dist-in 8.5144 APE11-dist-in 10.8334 APE10-dist-in 5.0923 APE9-dist-in 3.2931 None TPO190 TPO190 XRAY 2.4 0.167 0.226 A 310.0 289.0 0 28 28 0 [[36, 286]] 1.0 4qmv Homo sapiens STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24

Ligand: 34W

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name