Ligand: 29L

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 75.0% 6U2HD
DFGin None 2 25.0% 8CHFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 6U2HC P15056 448 733 766.0 29L:60801 Type1 Inactive DFGin 6.7505 14.2365 BLAminus -140.81, -173.87 57.62, 73.3 -90.9, 27.8 291.38, 51.17 -64.94, -25.09 in-in in 8.6241 Saltbr-in 2.732 HRD-in -81.66, -40.52 63.75, 1.44 in-in-out SNCiio in-out ActLoopNT-in 2.8312 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -6.73 APE8-dihe-in -77.44, 81.11 APE8-rot-in 298.33 APE67-dihe-in -77.58, -10.43 -81.03, -23.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.3688 None SEP729 SEP729 XRAY 2.5 0.222 0.263 C 290.0 275.0 11 30 19 11 [[457, 716]] 1.0 6u2h TKL_BRAF_HUMAN TKL 5.2e-84 287.9 4.0 267.0 264.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2HD P15056 448 733 766.0 29L:60801 Type1 Inactive DFGin 6.3619 13.8526 BLAminus -135.68, 175.39 64.72, 81.19 -94.93, 22.46 283.79, 66.21 -67.34, -30.28 in-in in 8.5988 Saltbr-in 2.7798 HRD-in -78.94, -38.38 63.06, 1.76 in-in-out SNCiio in-out ActLoopNT-in 2.9596 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 55.45, -147.38 APE9-dihe-na -70.68, -35.18 APE8-dihe-in -76.57, 92.11 APE8-rot-out 85.56 APE67-dihe-in -62.26, -37.46 -120.91, -2.65 APE12-dist-in 8.8315 APE11-dist-in 9.5034 APE10-dist-out 11.3875 APE9-dist-out 11.5826 None SEP729 SEP729 XRAY 2.5 0.222 0.263 D 290.0 283.0 3 30 27 3 [[457, 716]] 1.0 6u2h TKL_BRAF_HUMAN TKL 5.2e-84 287.9 4.0 267.0 264.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVA P15056 449 721 766.0 29L:60801 Type1 Inactive DFGin 7.1485 13.9747 BLAminus -147.63, -169.13 58.79, 78.75 -106.95, 34.37 285.73, 83.49 -85.44, -39.06 in-in in 8.58 Saltbr-in 2.6065 HRD-in -66.2, -50.26 77.35, -0.9 in-in-out SNCiio in-out ActLoopNT-in 2.9123 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnio APE10-dihe-na 999.0, -52.91 APE9-dihe-na 60.55, -7.98 APE8-dihe-in -83.24, 65.36 APE8-rot-out 38.35 APE67-dihe-in -63.32, -24.58 -66.92, -44.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.9594 APE9-dist-out 9.4973 None None None XRAY 2.88 0.221 0.242 A 308.0 261.0 12 30 18 12 [[457, 716]] 1.0 7shv TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFA P15056 449 720 766.0 29L:801 Type1 None DFGin 6.8311 14.0843 BLAminus -138.14, -173.65 64.87, 78.28 -102.21, 29.93 290.33, 73.26 -66.38, -51.46 in-in in 8.5816 Saltbr-in 2.7679 HRD-in -70.14, -50.01 76.68, -10.07 in-in-none SNCiin in-none ActLoopNT-in 2.834 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 142.76 APE8-rot-in 296.87 APE67-dihe-in -62.48, -28.21 -57.0, -49.39 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 V600E None None XRAY 2.802 0.215 0.275 A 329.0 257.0 15 30 15 15 [[457, 716]] 1.0 4mnf TKL_BRAF_HUMAN TKL 1.4e-81 279.9 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFB P15056 449 720 766.0 29L:801 Type1 Inactive DFGin 6.4856 13.9224 BLAminus -122.68, -176.93 63.73, 92.47 -110.65, 27.31 288.5, 68.83 -50.42, -45.23 in-in in 8.6987 Saltbr-in 2.8656 HRD-in -76.32, -52.93 74.07, 3.14 in-in-out SNCiio in-out ActLoopNT-in 3.0632 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 13.12 APE8-rot-out 79.33 APE67-dihe-in -65.4, -15.67 -79.06, -24.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 V600E None None XRAY 2.802 0.215 0.275 B 329.0 257.0 15 30 15 15 [[457, 716]] 1.0 4mnf TKL_BRAF_HUMAN TKL 1.4e-81 279.9 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVB P15056 449 721 766.0 29L:60801 Type1.5_Back Inactive DFGin 6.7358 14.1706 BLAminus -147.31, -168.46 59.95, 68.87 -90.82, 20.67 284.09, 50.14 -57.74, -56.04 in-in in 8.7709 Saltbr-in 2.8016 HRD-in -76.59, -37.99 67.86, -2.2 in-in-out SNCiio in-out ActLoopNT-in 2.8593 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnio APE10-dihe-na 999.0, -136.62 APE9-dihe-na -141.24, 15.82 APE8-dihe-in -103.28, 75.96 APE8-rot-in 280.52 APE67-dihe-in -56.94, -26.52 -73.16, -41.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3912 APE9-dist-out 9.4021 None None None XRAY 2.88 0.221 0.242 B 308.0 262.0 11 30 19 11 [[457, 716]] 1.0 7shv TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL RAF1 RAF1_HUMAN 8CHFA P04049 341 626 648.0 29L:60701 Type1 Inactive DFGin 6.9193 13.7979 None -77.69, -137.87 -62.1, 150.83 -123.34, 43.11 304.09, 90.48 -53.76, -47.63 in-out in 8.5922 Saltbr-out 6.6899 HRD-in -62.51, -43.32 69.96, -9.45 out-in-out SNCoio in-out ActLoopNT-in 2.8262 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na 55.74, 2.9 APE9-dihe-na 55.92, 40.68 APE8-dihe-in -131.33, 94.1 APE8-rot-out 59.25 APE67-dihe-inflip 81.42, -0.92 -97.97, 165.62 APE12-dist-in 7.3494 APE11-dist-in 11.6311 APE10-dist-in 6.9434 APE9-dist-out 10.1571 Y341D SEP621 SEP621 EM 4.25 0.445 999.0 A 648.0 280.0 6 30 24 6 [[349, 608]] 1.0 8chf TKL_RAF1_HUMAN TKL 3e-80 275.8 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CHFB P04049 341 626 648.0 29L:60701 Type1 Inactive DFGin 6.9191 13.7979 None -77.67, -137.85 -62.16, 150.83 -123.29, 43.03 304.08, 90.5 -53.73, -47.64 in-out in 8.5922 Saltbr-out 6.6905 HRD-in -62.53, -43.31 69.92, -9.4 out-in-out SNCoio in-out ActLoopNT-in 2.8268 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na 55.74, 2.9 APE9-dihe-na 55.89, 40.65 APE8-dihe-in -131.28, 94.15 APE8-rot-out 59.25 APE67-dihe-inflip 81.39, -0.89 -98.01, 165.61 APE12-dist-in 7.3494 APE11-dist-in 11.631 APE10-dist-in 6.9423 APE9-dist-out 10.1569 Y341D SEP621 SEP621 EM 4.25 0.445 999.0 B 648.0 280.0 6 30 24 6 [[349, 608]] 1.0 8chf TKL_RAF1_HUMAN TKL 3e-80 275.8 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

Ligand: 29L

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 75.0% 6U2HD
DFGin None 2 25.0% 8CHFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 6U2HC P15056 448 733 766.0 29L:60801 Type1 Inactive DFGin 6.7505 14.2365 BLAminus -140.81, -173.87 57.62, 73.3 -90.9, 27.8 291.38, 51.17 -64.94, -25.09 in-in in 8.6241 Saltbr-in 2.732 HRD-in -81.66, -40.52 63.75, 1.44 in-in-out SNCiio in-out ActLoopNT-in 2.8312 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -6.73 APE8-dihe-in -77.44, 81.11 APE8-rot-in 298.33 APE67-dihe-in -77.58, -10.43 -81.03, -23.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.3688 None SEP729 SEP729 XRAY 2.5 0.222 0.263 C 290.0 275.0 11 30 19 11 [[457, 716]] 1.0 6u2h Homo sapiens TKL_BRAF_HUMAN TKL 5.2e-84 287.9 4.0 267.0 264.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2HD P15056 448 733 766.0 29L:60801 Type1 Inactive DFGin 6.3619 13.8526 BLAminus -135.68, 175.39 64.72, 81.19 -94.93, 22.46 283.79, 66.21 -67.34, -30.28 in-in in 8.5988 Saltbr-in 2.7798 HRD-in -78.94, -38.38 63.06, 1.76 in-in-out SNCiio in-out ActLoopNT-in 2.9596 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 55.45, -147.38 APE9-dihe-na -70.68, -35.18 APE8-dihe-in -76.57, 92.11 APE8-rot-out 85.56 APE67-dihe-in -62.26, -37.46 -120.91, -2.65 APE12-dist-in 8.8315 APE11-dist-in 9.5034 APE10-dist-out 11.3875 APE9-dist-out 11.5826 None SEP729 SEP729 XRAY 2.5 0.222 0.263 D 290.0 283.0 3 30 27 3 [[457, 716]] 1.0 6u2h Homo sapiens TKL_BRAF_HUMAN TKL 5.2e-84 287.9 4.0 267.0 264.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVA P15056 449 721 766.0 29L:60801 Type1 Inactive DFGin 7.1485 13.9747 BLAminus -147.63, -169.13 58.79, 78.75 -106.95, 34.37 285.73, 83.49 -85.44, -39.06 in-in in 8.58 Saltbr-in 2.6065 HRD-in -66.2, -50.26 77.35, -0.9 in-in-out SNCiio in-out ActLoopNT-in 2.9123 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnio APE10-dihe-na 999.0, -52.91 APE9-dihe-na 60.55, -7.98 APE8-dihe-in -83.24, 65.36 APE8-rot-out 38.35 APE67-dihe-in -63.32, -24.58 -66.92, -44.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.9594 APE9-dist-out 9.4973 None None None XRAY 2.88 0.221 0.242 A 308.0 261.0 12 30 18 12 [[457, 716]] 1.0 7shv Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFA P15056 449 720 766.0 29L:801 Type1 None DFGin 6.8311 14.0843 BLAminus -138.14, -173.65 64.87, 78.28 -102.21, 29.93 290.33, 73.26 -66.38, -51.46 in-in in 8.5816 Saltbr-in 2.7679 HRD-in -70.14, -50.01 76.68, -10.07 in-in-none SNCiin in-none ActLoopNT-in 2.834 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 142.76 APE8-rot-in 296.87 APE67-dihe-in -62.48, -28.21 -57.0, -49.39 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 V600E None None XRAY 2.802 0.215 0.275 A 329.0 257.0 15 30 15 15 [[457, 716]] 1.0 4mnf Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-81 279.9 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFB P15056 449 720 766.0 29L:801 Type1 Inactive DFGin 6.4856 13.9224 BLAminus -122.68, -176.93 63.73, 92.47 -110.65, 27.31 288.5, 68.83 -50.42, -45.23 in-in in 8.6987 Saltbr-in 2.8656 HRD-in -76.32, -52.93 74.07, 3.14 in-in-out SNCiio in-out ActLoopNT-in 3.0632 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 13.12 APE8-rot-out 79.33 APE67-dihe-in -65.4, -15.67 -79.06, -24.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 V600E None None XRAY 2.802 0.215 0.275 B 329.0 257.0 15 30 15 15 [[457, 716]] 1.0 4mnf Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-81 279.9 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVB P15056 449 721 766.0 29L:60801 Type1.5_Back Inactive DFGin 6.7358 14.1706 BLAminus -147.31, -168.46 59.95, 68.87 -90.82, 20.67 284.09, 50.14 -57.74, -56.04 in-in in 8.7709 Saltbr-in 2.8016 HRD-in -76.59, -37.99 67.86, -2.2 in-in-out SNCiio in-out ActLoopNT-in 2.8593 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnio APE10-dihe-na 999.0, -136.62 APE9-dihe-na -141.24, 15.82 APE8-dihe-in -103.28, 75.96 APE8-rot-in 280.52 APE67-dihe-in -56.94, -26.52 -73.16, -41.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3912 APE9-dist-out 9.4021 None None None XRAY 2.88 0.221 0.242 B 308.0 262.0 11 30 19 11 [[457, 716]] 1.0 7shv Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL RAF1 RAF1_HUMAN 8CHFA P04049 341 626 648.0 29L:60701 Type1 Inactive DFGin 6.9193 13.7979 None -77.69, -137.87 -62.1, 150.83 -123.34, 43.11 304.09, 90.48 -53.76, -47.63 in-out in 8.5922 Saltbr-out 6.6899 HRD-in -62.51, -43.32 69.96, -9.45 out-in-out SNCoio in-out ActLoopNT-in 2.8262 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na 55.74, 2.9 APE9-dihe-na 55.92, 40.68 APE8-dihe-in -131.33, 94.1 APE8-rot-out 59.25 APE67-dihe-inflip 81.42, -0.92 -97.97, 165.62 APE12-dist-in 7.3494 APE11-dist-in 11.6311 APE10-dist-in 6.9434 APE9-dist-out 10.1571 Y341D SEP621 SEP621 EM 4.25 0.445 999.0 A 648.0 280.0 6 30 24 6 [[349, 608]] 1.0 8chf Homo sapiens TKL_RAF1_HUMAN TKL 3e-80 275.8 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CHFB P04049 341 626 648.0 29L:60701 Type1 Inactive DFGin 6.9191 13.7979 None -77.67, -137.85 -62.16, 150.83 -123.29, 43.03 304.08, 90.5 -53.73, -47.64 in-out in 8.5922 Saltbr-out 6.6905 HRD-in -62.53, -43.31 69.92, -9.4 out-in-out SNCoio in-out ActLoopNT-in 2.8268 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na 55.74, 2.9 APE9-dihe-na 55.89, 40.65 APE8-dihe-in -131.28, 94.15 APE8-rot-out 59.25 APE67-dihe-inflip 81.39, -0.89 -98.01, 165.61 APE12-dist-in 7.3494 APE11-dist-in 11.631 APE10-dist-in 6.9423 APE9-dist-out 10.1569 Y341D SEP621 SEP621 EM 4.25 0.445 999.0 B 648.0 280.0 6 30 24 6 [[349, 608]] 1.0 8chf Homo sapiens TKL_RAF1_HUMAN TKL 3e-80 275.8 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

Ligand: 29L

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name