Ligand: 23D

Total number of chains: 5
Active chains: 4
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 2F57B
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CK1 CSNK1G3 KC1G3_HUMAN 2IZTA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 23D Type1 37 - 334 0 None None Casein kinase I isoform gamma-3
CMGC CDK2 CDK2_HUMAN 6GUFA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6GUFC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 1 - 297 0 TPO160 None Cyclin-dependent kinase 2
STE PAK4 PAK4_HUMAN 2CDZA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 299 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK5 PAK5_HUMAN 2F57B 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 425 - 718 0 SEP602 None Serine/threonine-protein kinase PAK 5

Ligand: 23D

Total number of chains: 5
Active chains: 4
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 2F57B
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CK1 CSNK1G3 KC1G3_HUMAN 2IZTA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 23D Type1 37 - 334 0 None None Casein kinase I isoform gamma-3 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6GUFA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6GUFC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 1 - 297 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
STE PAK4 PAK4_HUMAN 2CDZA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 299 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK5 PAK5_HUMAN 2F57B 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 23D Type1 425 - 718 0 SEP602 None Serine/threonine-protein kinase PAK 5 Homo sapiens

Ligand: 23D

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page
Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism