Ligand: 16W

Total number of chains: 4
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 4HNFB
DFGout BBAminus 2 50.0% 4HNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 CSNK1D KC1D_HUMAN 4HNFA P48730 3 294 415.0 16W:301 Type1 Active DFGin 6.575 15.8043 BLAminus -129.62, -172.35 54.61, 82.41 -100.04, 26.99 293.51, 69.72 -59.68, -32.76 in-in in 8.6166 Saltbr-in 3.254 HRD-in -66.07, -51.92 76.62, -0.09 in-in-in SNCiii in-in ActLoopNT-in 3.1421 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 21.82 APE9-dihe-na -154.45, -143.25 APE8-dihe-in -85.78, 141.82 APE8-rot-in 301.59 APE67-dihe-in -65.11, -35.21 -83.43, -20.7 APE12-dist-in 13.0218 APE11-dist-in 12.3662 APE10-dist-in 7.1467 APE9-dist-in 4.2023 None None None XRAY 2.07 0.241 0.274 A 296.0 289.0 3 35 35 0 [[9, 275]] 1.0 4hnf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 4HNFB P48730 5 294 415.0 16W:301 Type1 Inactive DFGin 6.5553 15.8656 BLAminus -134.11, -166.41 56.81, 78.35 -103.18, 26.32 281.92, 77.82 -64.45, -33.31 in-out in 8.6394 Saltbr-out 4.6224 HRD-in -79.26, -38.92 65.6, -2.59 out-in-in SNCoii in-in ActLoopNT-in 2.9871 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.72, 118.09 APE9-dihe-na 133.0, -140.96 APE8-dihe-in -114.37, 128.18 APE8-rot-in 299.03 APE67-dihe-in -47.74, -37.42 -57.39, -49.8 APE12-dist-in 12.6047 APE11-dist-in 11.8192 APE10-dist-in 6.0185 APE9-dist-in 4.7109 None None None XRAY 2.07 0.241 0.274 B 296.0 290.0 0 35 35 0 [[9, 275]] 1.0 4hnf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1E KC1E_HUMAN 4HNIA P49674 3 293 416.0 16W:301 Type1 Inactive DFGout 12.8676 8.8609 BBAminus -119.65, 137.22 -111.91, 132.84 -104.81, -19.65 286.96, 103.48 159.07, -5.48 in-none in 8.3199 Saltbr-none 999.0 HRD-in -67.14, -49.26 72.96, 2.33 none-in-in SNCnii in-in ActLoopNT-in 3.0558 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.92, 132.71 APE9-dihe-na 88.82, 170.71 APE8-dihe-in -66.44, 133.81 APE8-rot-in 310.46 APE67-dihe-in -51.3, -32.55 -59.56, -48.57 APE12-dist-in 13.2068 APE11-dist-in 12.3803 APE10-dist-in 7.0821 APE9-dist-in 3.6082 None None None XRAY 2.74 0.237 0.273 A 296.0 284.0 7 35 35 0 [[9, 275]] 1.0 4hni CK1_CSNK1E_HUMAN CK1 7.3e-123 415.0 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform epsilon
CK1 CSNK1E KC1E_HUMAN 4HNIB P49674 1 293 416.0 16W:301 Type1 Inactive DFGout 13.1423 8.7371 BBAminus -116.99, 143.58 -113.13, 121.05 -91.56, -9.39 289.37, 83.53 143.22, 6.36 in-none in 8.0231 Saltbr-none 999.0 HRD-in -78.57, -39.07 66.3, -1.34 none-in-in SNCnii in-in ActLoopNT-in 2.9481 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.23, 129.06 APE9-dihe-na 102.35, 170.75 APE8-dihe-in -61.99, 145.38 APE8-rot-in 291.89 APE67-dihe-in -61.87, -34.12 -72.52, -36.41 APE12-dist-in 12.3206 APE11-dist-in 12.3147 APE10-dist-in 6.8442 APE9-dist-in 3.6958 None None None XRAY 2.74 0.237 0.273 B 296.0 284.0 9 35 35 0 [[9, 275]] 1.0 4hni CK1_CSNK1E_HUMAN CK1 7.3e-123 415.0 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform epsilon

Ligand: 16W

Total number of chains: 4
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 4HNFB
DFGout BBAminus 2 50.0% 4HNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 CSNK1D KC1D_HUMAN 4HNFA P48730 3 294 415.0 16W:301 Type1 Active DFGin 6.575 15.8043 BLAminus -129.62, -172.35 54.61, 82.41 -100.04, 26.99 293.51, 69.72 -59.68, -32.76 in-in in 8.6166 Saltbr-in 3.254 HRD-in -66.07, -51.92 76.62, -0.09 in-in-in SNCiii in-in ActLoopNT-in 3.1421 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 21.82 APE9-dihe-na -154.45, -143.25 APE8-dihe-in -85.78, 141.82 APE8-rot-in 301.59 APE67-dihe-in -65.11, -35.21 -83.43, -20.7 APE12-dist-in 13.0218 APE11-dist-in 12.3662 APE10-dist-in 7.1467 APE9-dist-in 4.2023 None None None XRAY 2.07 0.241 0.274 A 296.0 289.0 3 35 35 0 [[9, 275]] 1.0 4hnf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 4HNFB P48730 5 294 415.0 16W:301 Type1 Inactive DFGin 6.5553 15.8656 BLAminus -134.11, -166.41 56.81, 78.35 -103.18, 26.32 281.92, 77.82 -64.45, -33.31 in-out in 8.6394 Saltbr-out 4.6224 HRD-in -79.26, -38.92 65.6, -2.59 out-in-in SNCoii in-in ActLoopNT-in 2.9871 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.72, 118.09 APE9-dihe-na 133.0, -140.96 APE8-dihe-in -114.37, 128.18 APE8-rot-in 299.03 APE67-dihe-in -47.74, -37.42 -57.39, -49.8 APE12-dist-in 12.6047 APE11-dist-in 11.8192 APE10-dist-in 6.0185 APE9-dist-in 4.7109 None None None XRAY 2.07 0.241 0.274 B 296.0 290.0 0 35 35 0 [[9, 275]] 1.0 4hnf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1E KC1E_HUMAN 4HNIA P49674 3 293 416.0 16W:301 Type1 Inactive DFGout 12.8676 8.8609 BBAminus -119.65, 137.22 -111.91, 132.84 -104.81, -19.65 286.96, 103.48 159.07, -5.48 in-none in 8.3199 Saltbr-none 999.0 HRD-in -67.14, -49.26 72.96, 2.33 none-in-in SNCnii in-in ActLoopNT-in 3.0558 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.92, 132.71 APE9-dihe-na 88.82, 170.71 APE8-dihe-in -66.44, 133.81 APE8-rot-in 310.46 APE67-dihe-in -51.3, -32.55 -59.56, -48.57 APE12-dist-in 13.2068 APE11-dist-in 12.3803 APE10-dist-in 7.0821 APE9-dist-in 3.6082 None None None XRAY 2.74 0.237 0.273 A 296.0 284.0 7 35 35 0 [[9, 275]] 1.0 4hni Homo sapiens CK1_CSNK1E_HUMAN CK1 7.3e-123 415.0 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform epsilon
CK1 CSNK1E KC1E_HUMAN 4HNIB P49674 1 293 416.0 16W:301 Type1 Inactive DFGout 13.1423 8.7371 BBAminus -116.99, 143.58 -113.13, 121.05 -91.56, -9.39 289.37, 83.53 143.22, 6.36 in-none in 8.0231 Saltbr-none 999.0 HRD-in -78.57, -39.07 66.3, -1.34 none-in-in SNCnii in-in ActLoopNT-in 2.9481 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.23, 129.06 APE9-dihe-na 102.35, 170.75 APE8-dihe-in -61.99, 145.38 APE8-rot-in 291.89 APE67-dihe-in -61.87, -34.12 -72.52, -36.41 APE12-dist-in 12.3206 APE11-dist-in 12.3147 APE10-dist-in 6.8442 APE9-dist-in 3.6958 None None None XRAY 2.74 0.237 0.273 B 296.0 284.0 9 35 35 0 [[9, 275]] 1.0 4hni Homo sapiens CK1_CSNK1E_HUMAN CK1 7.3e-123 415.0 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform epsilon

Ligand: 16W

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name