Ligand: 03P

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3RCDA
DFGin BLAminus 1 25.0% 3W2OA
DFGin BLBplus 1 25.0% 3POZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3W2OA P00533 698 1017 1210.0 03P:61101 Type1.5_Front Inactive DFGin 6.0628 16.8526 BLAminus -136.96, -170.56 62.22, 87.75 -101.43, 18.89 291.4, 91.83 -57.44, -26.38 out-out out 10.6755 Saltbr-out 8.5233 HRD-in -77.47, -53.25 75.27, 2.22 out-in-in SNCoii in-in ActLoopNT-in 2.8878 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.73, 104.36 APE9-dihe-in -123.36, 141.58 APE8-dihe-in -79.92, 73.45 APE8-rot-na 24.57 APE67-dihe-in -74.19, -6.86 -50.44, -40.99 APE12-dist-na 11.6864 APE11-dist-na 11.2596 APE10-dist-na 10.5588 APE9-dist-in 7.2229 T790M,L858R None None XRAY 2.35 0.182 0.216 A 331.0 304.0 0 30 30 0 [[712, 970]] 1.0 3w2o TYR_EGFR_HUMAN TYR 8.7e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA P00533 701 1017 1210.0 03P:1023 Type1.5_Back Inactive DFGin 4.4506 13.643 BLBplus -134.04, 177.92 66.76, 22.09 -77.01, 146.77 49.04, 92.91 73.32, 4.89 out-out out 14.0479 Saltbr-out 14.5936 HRD-in -70.57, -55.32 77.16, -8.09 out-out-none SNCoon out-none ActLoopNT-out 6.2941 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 142.54 APE9-dihe-in -117.89, 144.54 APE8-dihe-in -79.69, 70.35 APE8-rot-na 31.29 APE67-dihe-in -71.87, -5.08 -51.91, -42.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8705 APE9-dist-in 7.5678 None None None XRAY 1.5 0.22 0.243 A 327.0 293.0 18 30 23 7 [[712, 970]] 1.0 3poz TYR_EGFR_HUMAN TYR 1e-87 299.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB2 ERBB2_HUMAN 3RCDA P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.3275 12.7836 None -131.6, -178.33 92.87, -78.83 17.87, 80.88 36.71, 96.9 175.62, 84.65 out-out out 12.7748 Saltbr-out 10.1037 HRD-in -81.36, -50.25 83.34, -29.6 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 32.08 APE8-dihe-in -80.8, 92.84 APE8-rot-na 32.85 APE67-dihe-in -72.62, -9.61 -71.44, -35.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.7735 None None None XRAY 3.21 0.227 0.294 A 338.0 278.0 21 30 13 17 [[720, 978]] 1.0 3rcd TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2.0 260.0 259.0 862 863 864 866 868 753 770 774 842 844 843 845.0 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.2988 12.8076 None -129.48, -177.14 93.53, -78.44 17.53, 81.66 36.39, 96.61 174.11, 84.1 out-out out 12.7623 Saltbr-out 10.1811 HRD-in -79.56, -52.25 82.81, -26.53 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 30.75 APE8-dihe-in -78.7, 91.19 APE8-rot-na 32.27 APE67-dihe-in -71.69, -11.86 -69.94, -35.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.6837 None None None XRAY 3.21 0.227 0.294 C 338.0 278.0 21 30 13 17 [[720, 978]] 1.0 3rcd TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2.0 260.0 259.0 862 863 864 866 868 753 770 774 842 844 843 845.0 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2

Ligand: 03P

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3RCDA
DFGin BLAminus 1 25.0% 3W2OA
DFGin BLBplus 1 25.0% 3POZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3W2OA P00533 698 1017 1210.0 03P:61101 Type1.5_Front Inactive DFGin 6.0628 16.8526 BLAminus -136.96, -170.56 62.22, 87.75 -101.43, 18.89 291.4, 91.83 -57.44, -26.38 out-out out 10.6755 Saltbr-out 8.5233 HRD-in -77.47, -53.25 75.27, 2.22 out-in-in SNCoii in-in ActLoopNT-in 2.8878 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.73, 104.36 APE9-dihe-in -123.36, 141.58 APE8-dihe-in -79.92, 73.45 APE8-rot-na 24.57 APE67-dihe-in -74.19, -6.86 -50.44, -40.99 APE12-dist-na 11.6864 APE11-dist-na 11.2596 APE10-dist-na 10.5588 APE9-dist-in 7.2229 T790M,L858R None None XRAY 2.35 0.182 0.216 A 331.0 304.0 0 30 30 0 [[712, 970]] 1.0 3w2o Homo sapiens TYR_EGFR_HUMAN TYR 8.7e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA P00533 701 1017 1210.0 03P:1023 Type1.5_Back Inactive DFGin 4.4506 13.643 BLBplus -134.04, 177.92 66.76, 22.09 -77.01, 146.77 49.04, 92.91 73.32, 4.89 out-out out 14.0479 Saltbr-out 14.5936 HRD-in -70.57, -55.32 77.16, -8.09 out-out-none SNCoon out-none ActLoopNT-out 6.2941 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 142.54 APE9-dihe-in -117.89, 144.54 APE8-dihe-in -79.69, 70.35 APE8-rot-na 31.29 APE67-dihe-in -71.87, -5.08 -51.91, -42.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8705 APE9-dist-in 7.5678 None None None XRAY 1.5 0.22 0.243 A 327.0 293.0 18 30 23 7 [[712, 970]] 1.0 3poz Homo sapiens TYR_EGFR_HUMAN TYR 1e-87 299.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB2 ERBB2_HUMAN 3RCDA P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.3275 12.7836 None -131.6, -178.33 92.87, -78.83 17.87, 80.88 36.71, 96.9 175.62, 84.65 out-out out 12.7748 Saltbr-out 10.1037 HRD-in -81.36, -50.25 83.34, -29.6 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 32.08 APE8-dihe-in -80.8, 92.84 APE8-rot-na 32.85 APE67-dihe-in -72.62, -9.61 -71.44, -35.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.7735 None None None XRAY 3.21 0.227 0.294 A 338.0 278.0 21 30 13 17 [[720, 978]] 1.0 3rcd Homo sapiens TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2.0 260.0 259.0 862 863 864 866 868 753 770 774 842 844 843 845.0 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.2988 12.8076 None -129.48, -177.14 93.53, -78.44 17.53, 81.66 36.39, 96.61 174.11, 84.1 out-out out 12.7623 Saltbr-out 10.1811 HRD-in -79.56, -52.25 82.81, -26.53 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 30.75 APE8-dihe-in -78.7, 91.19 APE8-rot-na 32.27 APE67-dihe-in -71.69, -11.86 -69.94, -35.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.6837 None None None XRAY 3.21 0.227 0.294 C 338.0 278.0 21 30 13 17 [[720, 978]] 1.0 3rcd Homo sapiens TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2.0 260.0 259.0 862 863 864 866 868 753 770 774 842 844 843 845.0 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2

Ligand: 03P

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name