Ligand: 03P

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3RCDA
DFGin BLAminus 1 25.0% 3W2OA
DFGin BLBplus 1 25.0% 3POZA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3W2OA P00533 698 1017 1210.0 03P:61101 Type1.5_Front Inactive DFGin 6.063 16.853 BLAminus -136.96, -170.56 62.22, 87.75 -101.43, 18.89 291.4, 91.83 -57.44, -26.38 out-out out 10.675 Saltbr-out 8.523 HRD-in -77.47, -53.25 75.27, 2.22 out-in-in SNCoii in-in ActLoopNT-in 2.888 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.73, 104.36 APE9-dihe-in -123.36, 141.58 APE8-dihe-in -79.92, 73.45 APE8-rot-na 24.57 APE67-dihe-in -74.19, -6.86 -50.44, -40.99 APE12-dist-na 11.686 APE11-dist-na 11.26 APE10-dist-na 10.559 APE9-dist-in 7.223 T790M,L858R None None XRAY 2.35 0.182 0.216 A 331 304 0 0 0 0 [[712, 970]] 1.0 3w2o TYR_EGFR_HUMAN TYR 8.7e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA P00533 701 1017 1210.0 03P:1023 Type1.5_Back Inactive DFGin 4.451 13.643 BLBplus -134.04, 177.92 66.76, 22.09 -77.01, 146.77 49.04, 92.91 73.32, 4.89 out-out out 14.048 Saltbr-out 14.594 HRD-in -70.57, -55.32 77.16, -8.09 out-out-none SNCoon out-none ActLoopNT-out 6.294 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 142.54 APE9-dihe-in -117.89, 144.54 APE8-dihe-in -79.69, 70.35 APE8-rot-na 31.29 APE67-dihe-in -71.87, -5.08 -51.91, -42.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.87 APE9-dist-in 7.568 None None None XRAY 1.5 0.22 0.243 A 327 293 18 0 0 7 [[712, 970]] 1.0 3poz TYR_EGFR_HUMAN TYR 1e-87 299.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB2 ERBB2_HUMAN 3RCDA P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.327 12.784 None -131.6, -178.33 92.87, -78.83 17.87, 80.88 36.71, 96.9 175.62, 84.65 out-out out 12.775 Saltbr-out 10.104 HRD-in -81.36, -50.25 83.34, -29.6 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 32.08 APE8-dihe-in -80.8, 92.84 APE8-rot-na 32.85 APE67-dihe-in -72.62, -9.61 -71.44, -35.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.774 None None None XRAY 3.21 0.227 0.294 A 338 278 21 0 0 17 [[720, 978]] 1.0 3rcd TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2 260 259 862 863 864 866 868 753 770 774 842 844 843 845 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.299 12.808 None -129.48, -177.14 93.53, -78.44 17.53, 81.66 36.39, 96.61 174.11, 84.1 out-out out 12.762 Saltbr-out 10.181 HRD-in -79.56, -52.25 82.81, -26.53 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 30.75 APE8-dihe-in -78.7, 91.19 APE8-rot-na 32.27 APE67-dihe-in -71.69, -11.86 -69.94, -35.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.684 None None None XRAY 3.21 0.227 0.294 C 338 278 21 0 0 17 [[720, 978]] 1.0 3rcd TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2 260 259 862 863 864 866 868 753 770 774 842 844 843 845 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2

Ligand: 03P

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3RCDA
DFGin BLAminus 1 25.0% 3W2OA
DFGin BLBplus 1 25.0% 3POZA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3W2OA P00533 698 1017 1210.0 03P:61101 Type1.5_Front Inactive DFGin 6.063 16.853 BLAminus -136.96, -170.56 62.22, 87.75 -101.43, 18.89 291.4, 91.83 -57.44, -26.38 out-out out 10.675 Saltbr-out 8.523 HRD-in -77.47, -53.25 75.27, 2.22 out-in-in SNCoii in-in ActLoopNT-in 2.888 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.73, 104.36 APE9-dihe-in -123.36, 141.58 APE8-dihe-in -79.92, 73.45 APE8-rot-na 24.57 APE67-dihe-in -74.19, -6.86 -50.44, -40.99 APE12-dist-na 11.686 APE11-dist-na 11.26 APE10-dist-na 10.559 APE9-dist-in 7.223 T790M,L858R None None XRAY 2.35 0.182 0.216 A 331 304 0 0 0 0 [[712, 970]] 1.0 3w2o Homo sapiens TYR_EGFR_HUMAN TYR 8.7e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA P00533 701 1017 1210.0 03P:1023 Type1.5_Back Inactive DFGin 4.451 13.643 BLBplus -134.04, 177.92 66.76, 22.09 -77.01, 146.77 49.04, 92.91 73.32, 4.89 out-out out 14.048 Saltbr-out 14.594 HRD-in -70.57, -55.32 77.16, -8.09 out-out-none SNCoon out-none ActLoopNT-out 6.294 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 142.54 APE9-dihe-in -117.89, 144.54 APE8-dihe-in -79.69, 70.35 APE8-rot-na 31.29 APE67-dihe-in -71.87, -5.08 -51.91, -42.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.87 APE9-dist-in 7.568 None None None XRAY 1.5 0.22 0.243 A 327 293 18 0 0 7 [[712, 970]] 1.0 3poz Homo sapiens TYR_EGFR_HUMAN TYR 1e-87 299.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB2 ERBB2_HUMAN 3RCDA P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.327 12.784 None -131.6, -178.33 92.87, -78.83 17.87, 80.88 36.71, 96.9 175.62, 84.65 out-out out 12.775 Saltbr-out 10.104 HRD-in -81.36, -50.25 83.34, -29.6 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 32.08 APE8-dihe-in -80.8, 92.84 APE8-rot-na 32.85 APE67-dihe-in -72.62, -9.61 -71.44, -35.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.774 None None None XRAY 3.21 0.227 0.294 A 338 278 21 0 0 17 [[720, 978]] 1.0 3rcd Homo sapiens TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2 260 259 862 863 864 866 868 753 770 774 842 844 843 845 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC P04626 713 1022 1255.0 03P:69001 Type1.5_Back Inactive DFGin 7.299 12.808 None -129.48, -177.14 93.53, -78.44 17.53, 81.66 36.39, 96.61 174.11, 84.1 out-out out 12.762 Saltbr-out 10.181 HRD-in -79.56, -52.25 82.81, -26.53 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 30.75 APE8-dihe-in -78.7, 91.19 APE8-rot-na 32.27 APE67-dihe-in -71.69, -11.86 -69.94, -35.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.684 None None None XRAY 3.21 0.227 0.294 C 338 278 21 0 0 17 [[720, 978]] 1.0 3rcd Homo sapiens TYR_ERBB2_HUMAN TYR 8.5e-86 293.4 2 260 259 862 863 864 866 868 753 770 774 842 844 843 845 904 892 887 886 885 884 883 882 881 799 Receptor tyrosine-protein kinase erbB-2

Ligand: 03P

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name