AGC_STK38 (Serine/threonine-protein kinase 38)

Total number of chains: 4
Active chains: 2
Uniprot: STK38_HUMAN
Kinase Domain Residues: 89 - 382
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q15208-K1A
DFGin None 2 50.0% 6BXIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STK38 AF-Q15208-K1A Q15208 81 390 465.0 No_ligand No_ligand Active DFGin 6.2592 13.0725 BLAminus -134.61, 173.44 54.06, 73.9 -81.72, 14.99 305.51, 100.34 -63.52, -18.16 in-in in 8.7156 Saltbr-in 2.5953 HRD-in -72.89, -52.36 66.95, 13.5 in-in-in SNCiii in-in ActLoopNT-in 3.0047 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.32, 156.98 APE9-dihe-na 128.63, -175.74 APE8-dihe-in -93.85, 123.58 APE8-rot-in 301.4 APE67-dihe-in -70.52, -20.09 -45.54, -41.13 APE12-dist-in 8.6692 APE11-dist-in 11.6163 APE10-dist-in 5.7299 APE9-dist-in 3.3292 None None None AF2 -1.0 1.0 1.0 A 310.0 310.0 0 63 63 0 [[89, 382]] 1.0 AF-Q15208-K1 AGC_STK38_HUMAN AGC 2.1e-98 334.5 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 AF-Q15208-K3A Q15208 81 390 465.0 No_ligand No_ligand Active DFGin 6.2741 12.8977 BLAminus -140.2, -177.63 50.78, 63.8 -70.85, 11.95 306.06, 111.32 -64.39, -16.5 in-in in 8.6676 Saltbr-in 2.6133 HRD-in -73.09, -52.84 69.33, 0.49 in-in-in SNCiii in-in ActLoopNT-in 2.9757 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.04, 152.58 APE9-dihe-na 134.45, 168.77 APE8-dihe-in -78.44, 129.3 APE8-rot-in 298.45 APE67-dihe-in -74.77, -20.02 -52.75, -38.1 APE12-dist-in 8.7158 APE11-dist-in 11.6201 APE10-dist-in 5.7394 APE9-dist-in 3.2083 None None None AF2 -1.0 1.0 1.0 A 310.0 310.0 0 63 63 0 [[89, 382]] 1.0 AF-Q15208-K3 AGC_STK38_HUMAN AGC 2.1e-98 334.5 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 6BXIA Q15208 82 414 465.0 ANP:501 ATPlike Inactive DFGin 7.6243 15.2423 None -66.11, 165.54 -58.06, 132.91 -140.43, 160.91 66.01, 93.84 127.58, -39.07 out-out out 17.2238 Saltbr-out 15.8035 HRD-out -81.74, 95.52 -90.45, 26.47 out-out-out SNCooo out-out ActLoopNT-out 8.4633 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -99.6, -60.62 APE9-dihe-na 67.05, -156.06 APE8-dihe-in -145.17, 163.6 APE8-rot-out 65.89 APE67-dihe-in -50.28, -35.19 -91.75, 25.88 APE12-dist-out 17.3379 APE11-dist-out 14.2084 APE10-dist-out 17.7703 APE9-dist-out 12.1009 None None None XRAY 2.2 0.173 0.212 A 333.0 333.0 0 63 63 0 [[89, 382]] 1.0 6bxi AGC_STK38_HUMAN AGC 2.8e-98 334.1 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 6BXIB Q15208 83 414 465.0 ANP:501 ATPlike Inactive DFGin 7.5828 15.1791 None -72.08, 165.13 -53.35, 130.13 -138.87, 159.98 66.77, 96.29 126.01, -39.3 out-out out 17.1655 Saltbr-out 16.0645 HRD-out -84.3, 107.68 -100.32, 27.31 out-out-out SNCooo out-out ActLoopNT-out 8.4877 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -97.07, -63.08 APE9-dihe-na 73.07, -157.98 APE8-dihe-in -144.12, 160.82 APE8-rot-out 65.98 APE67-dihe-in -53.15, -35.39 -88.29, 27.93 APE12-dist-out 17.2389 APE11-dist-out 14.1835 APE10-dist-out 17.7413 APE9-dist-out 12.0524 None None None XRAY 2.2 0.173 0.212 B 333.0 332.0 0 63 63 0 [[89, 382]] 1.0 6bxi AGC_STK38_HUMAN AGC 2.8e-98 334.1 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38

AGC_STK38 (Serine/threonine-protein kinase 38)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q15208-K1A
DFGin None 2 50.0% 6BXIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STK38 STK38_HUMAN AF-Q15208-K1A Q15208 81 390 465.0 No_ligand No_ligand Active DFGin 6.2592 13.0725 BLAminus -134.61, 173.44 54.06, 73.9 -81.72, 14.99 305.51, 100.34 -63.52, -18.16 in-in in 8.7156 Saltbr-in 2.5953 HRD-in -72.89, -52.36 66.95, 13.5 in-in-in SNCiii in-in ActLoopNT-in 3.0047 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.32, 156.98 APE9-dihe-na 128.63, -175.74 APE8-dihe-in -93.85, 123.58 APE8-rot-in 301.4 APE67-dihe-in -70.52, -20.09 -45.54, -41.13 APE12-dist-in 8.6692 APE11-dist-in 11.6163 APE10-dist-in 5.7299 APE9-dist-in 3.3292 None None None AF2 -1.0 1.0 1.0 A 310.0 310.0 0 63 63 0 [[89, 382]] 1.0 AF-Q15208-K1 Homo sapiens AGC_STK38_HUMAN AGC 2.1e-98 334.5 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 STK38_HUMAN AF-Q15208-K3A Q15208 81 390 465.0 No_ligand No_ligand Active DFGin 6.2741 12.8977 BLAminus -140.2, -177.63 50.78, 63.8 -70.85, 11.95 306.06, 111.32 -64.39, -16.5 in-in in 8.6676 Saltbr-in 2.6133 HRD-in -73.09, -52.84 69.33, 0.49 in-in-in SNCiii in-in ActLoopNT-in 2.9757 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.04, 152.58 APE9-dihe-na 134.45, 168.77 APE8-dihe-in -78.44, 129.3 APE8-rot-in 298.45 APE67-dihe-in -74.77, -20.02 -52.75, -38.1 APE12-dist-in 8.7158 APE11-dist-in 11.6201 APE10-dist-in 5.7394 APE9-dist-in 3.2083 None None None AF2 -1.0 1.0 1.0 A 310.0 310.0 0 63 63 0 [[89, 382]] 1.0 AF-Q15208-K3 Homo sapiens AGC_STK38_HUMAN AGC 2.1e-98 334.5 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 STK38_HUMAN 6BXIA Q15208 82 414 465.0 ANP:501 ATPlike Inactive DFGin 7.6243 15.2423 None -66.11, 165.54 -58.06, 132.91 -140.43, 160.91 66.01, 93.84 127.58, -39.07 out-out out 17.2238 Saltbr-out 15.8035 HRD-out -81.74, 95.52 -90.45, 26.47 out-out-out SNCooo out-out ActLoopNT-out 8.4633 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -99.6, -60.62 APE9-dihe-na 67.05, -156.06 APE8-dihe-in -145.17, 163.6 APE8-rot-out 65.89 APE67-dihe-in -50.28, -35.19 -91.75, 25.88 APE12-dist-out 17.3379 APE11-dist-out 14.2084 APE10-dist-out 17.7703 APE9-dist-out 12.1009 None None None XRAY 2.2 0.173 0.212 A 333.0 333.0 0 63 63 0 [[89, 382]] 1.0 6bxi Homo sapiens AGC_STK38_HUMAN AGC 2.8e-98 334.1 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38
STK38 STK38_HUMAN 6BXIB Q15208 83 414 465.0 ANP:501 ATPlike Inactive DFGin 7.5828 15.1791 None -72.08, 165.13 -53.35, 130.13 -138.87, 159.98 66.77, 96.29 126.01, -39.3 out-out out 17.1655 Saltbr-out 16.0645 HRD-out -84.3, 107.68 -100.32, 27.31 out-out-out SNCooo out-out ActLoopNT-out 8.4877 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -97.07, -63.08 APE9-dihe-na 73.07, -157.98 APE8-dihe-in -144.12, 160.82 APE8-rot-out 65.98 APE67-dihe-in -53.15, -35.39 -88.29, 27.93 APE12-dist-out 17.2389 APE11-dist-out 14.1835 APE10-dist-out 17.7413 APE9-dist-out 12.0524 None None None XRAY 2.2 0.173 0.212 B 333.0 332.0 0 63 63 0 [[89, 382]] 1.0 6bxi Homo sapiens AGC_STK38_HUMAN AGC 2.8e-98 334.1 1.0 260.0 260.0 229 230 231 233 235 118 137 141 209 211 210 212.0 304 292 287 286 285 284 283 282 281 167 Serine/threonine-protein kinase 38

AGC_STK38 (Serine/threonine-protein kinase 38)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name