OTHER_RNASEL (2-5A-dependent ribonuclease)

Total number of chains: 3
Active chains: 0
Uniprot: RN5A_HUMAN
Kinase Domain Residues: 361 - 586
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4OAUC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RNASEL 4OAUC Q05823 25 719 741.0 ADP:801 ATPlike Pseudo DFGin 6.5293 12.3785 BLAminus -152.72, -178.03 59.98, 103.61 -125.32, 12.02 305.12, 98.0 -75.28, 8.76 in-in in 6.9931 Saltbr-in 2.6229 HRD-in -74.91, -47.94 67.23, 8.17 in-in-na SNCiia in-na ActLoopNT-in 2.9126 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -67.73, 111.98 APE9-dihe-na -66.2, -20.72 APE8-dihe-na -68.67, -28.85 APE8-rot-na 187.68 APE67-dihe-na -72.58, -38.81 -76.25, -36.54 APE12-dist-na 14.0675 APE11-dist-na 16.8747 APE10-dist-na 14.9848 APE9-dist-na 14.3331 H672N None None XRAY 2.6 0.213 0.251 C 699.0 692.0 0 20 20 0 [[353, 594]] 1.0 4oau OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease
RNASEL 4OAVB Q05823 24 717 741.0 ACP:801 ATPlike Pseudo DFGin 6.4754 12.3669 BLAminus -139.92, -178.5 65.74, 91.26 -114.98, 14.68 309.18, 101.1 -77.21, 3.69 in-in in 6.9053 Saltbr-in 2.7395 HRD-in -87.38, -45.25 69.13, -2.14 in-in-na SNCiia in-na ActLoopNT-in 3.0597 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -72.56, 102.63 APE9-dihe-na -56.52, -19.13 APE8-dihe-na -66.25, -31.04 APE8-rot-na 198.81 APE67-dihe-na -66.21, -44.37 -71.69, -39.0 APE12-dist-na 15.2929 APE11-dist-na 17.0118 APE10-dist-na 15.0202 APE9-dist-na 14.3961 H672N None None XRAY 2.1 0.2 0.229 B 699.0 673.0 8 20 20 0 [[353, 594]] 1.0 4oav OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease
RNASEL 4OAVD Q05823 26 719 741.0 ACP:1001 ATPlike Pseudo DFGin 6.5588 12.4049 BLAminus -138.71, -178.08 64.72, 95.25 -118.8, 14.99 306.98, 96.56 -77.32, 4.45 in-in in 6.904 Saltbr-in 2.919 HRD-in -73.82, -49.38 73.22, -2.68 in-in-na SNCiia in-na ActLoopNT-in 2.9151 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -72.59, 112.49 APE9-dihe-na -62.01, -29.18 APE8-dihe-na -62.89, -32.55 APE8-rot-na 188.49 APE67-dihe-na -70.07, -38.9 -67.42, -39.34 APE12-dist-na 14.651 APE11-dist-na 16.869 APE10-dist-na 14.6353 APE9-dist-na 14.3519 H672N None None XRAY 2.1 0.2 0.229 D 699.0 674.0 7 20 20 0 [[353, 594]] 1.0 4oav OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease

OTHER_RNASEL (2-5A-dependent ribonuclease)

Total number of chains: 23
Active chains: 12
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 65.2% 6M12b
DFGin ABAminus 8 34.8% 4O1PB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RNASEL RN5A_HUMAN 4OAUC Q05823 25 719 741.0 ADP:801 ATPlike Pseudo DFGin 6.5293 12.3785 BLAminus -152.72, -178.03 59.98, 103.61 -125.32, 12.02 305.12, 98.0 -75.28, 8.76 in-in in 6.9931 Saltbr-in 2.6229 HRD-in -74.91, -47.94 67.23, 8.17 in-in-na SNCiia in-na ActLoopNT-in 2.9126 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -67.73, 111.98 APE9-dihe-na -66.2, -20.72 APE8-dihe-na -68.67, -28.85 APE8-rot-na 187.68 APE67-dihe-na -72.58, -38.81 -76.25, -36.54 APE12-dist-na 14.0675 APE11-dist-na 16.8747 APE10-dist-na 14.9848 APE9-dist-na 14.3331 H672N None None XRAY 2.6 0.213 0.251 C 699.0 692.0 0 20 20 0 [[353, 594]] 1.0 4oau Homo sapiens OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease
RNASEL RN5A_HUMAN 4OAVB Q05823 24 717 741.0 ACP:801 ATPlike Pseudo DFGin 6.4754 12.3669 BLAminus -139.92, -178.5 65.74, 91.26 -114.98, 14.68 309.18, 101.1 -77.21, 3.69 in-in in 6.9053 Saltbr-in 2.7395 HRD-in -87.38, -45.25 69.13, -2.14 in-in-na SNCiia in-na ActLoopNT-in 3.0597 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -72.56, 102.63 APE9-dihe-na -56.52, -19.13 APE8-dihe-na -66.25, -31.04 APE8-rot-na 198.81 APE67-dihe-na -66.21, -44.37 -71.69, -39.0 APE12-dist-na 15.2929 APE11-dist-na 17.0118 APE10-dist-na 15.0202 APE9-dist-na 14.3961 H672N None None XRAY 2.1 0.2 0.229 B 699.0 673.0 8 20 20 0 [[353, 594]] 1.0 4oav Homo sapiens OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease
RNASEL RN5A_HUMAN 4OAVD Q05823 26 719 741.0 ACP:1001 ATPlike Pseudo DFGin 6.5588 12.4049 BLAminus -138.71, -178.08 64.72, 95.25 -118.8, 14.99 306.98, 96.56 -77.32, 4.45 in-in in 6.904 Saltbr-in 2.919 HRD-in -73.82, -49.38 73.22, -2.68 in-in-na SNCiia in-na ActLoopNT-in 2.9151 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -72.59, 112.49 APE9-dihe-na -62.01, -29.18 APE8-dihe-na -62.89, -32.55 APE8-rot-na 188.49 APE67-dihe-na -70.07, -38.9 -67.42, -39.34 APE12-dist-na 14.651 APE11-dist-na 16.869 APE10-dist-na 14.6353 APE9-dist-na 14.3519 H672N None None XRAY 2.1 0.2 0.229 D 699.0 674.0 7 20 20 0 [[353, 594]] 1.0 4oav Homo sapiens OTHER_RNASEL_HUMAN RNASEL 4.1e-136 459.9 1.0 242.0 242.0 502 503 504 506 508 392 404 408 482 484 483 485.0 520 522 517 516 515 514 513 512 511 435 2-5A-dependent ribonuclease
RNASEL A5H025_PIG 6M11A A5H025 22 727 743.0 25A:1000,B49:1001 Allosteric,Type1 Active DFGin 6.4775 12.988 BLAminus -155.56, -175.42 53.36, 69.23 -78.35, 0.82 299.16, 87.45 -44.61, -27.7 in-in in 6.9973 Saltbr-in 2.7597 HRD-in -77.65, -46.61 73.81, -8.63 in-in-na SNCiia in-na ActLoopNT-in 2.9186 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -150.91, 91.82 APE9-dihe-na -58.05, -29.31 APE8-dihe-na -85.86, 5.21 APE8-rot-na 81.56 APE67-dihe-na -49.78, -40.92 -78.75, -14.68 APE12-dist-na 15.8012 APE11-dist-na 12.511 APE10-dist-na 13.1969 APE9-dist-na 13.8976 None None None XRAY 2.46 0.223 0.285 a 717.0 681.0 3 20 20 0 [[351, 591]] 1.0 6m11 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M11B A5H025 23 727 743.0 25A:801,B49:802 Allosteric,Type1 Active DFGin 6.4307 12.9157 BLAminus -135.39, -175.08 63.06, 58.49 -90.2, 44.42 312.3, 86.88 -87.38, -12.11 in-in in 7.0656 Saltbr-in 2.7498 HRD-in -74.93, -49.19 77.69, -5.89 in-in-na SNCiia in-na ActLoopNT-in 2.8903 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -145.22, 69.59 APE9-dihe-na -60.88, -23.05 APE8-dihe-na -93.06, -0.03 APE8-rot-na 81.83 APE67-dihe-na -42.69, -43.6 -77.55, -16.15 APE12-dist-na 15.985 APE11-dist-na 13.983 APE10-dist-na 12.943 APE9-dist-na 14.252 None None None XRAY 2.46 0.223 0.285 b 717.0 684.0 0 20 20 0 [[351, 591]] 1.0 6m11 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M12B A5H025 24 726 743.0 25L:801,J60:802 Allosteric,Type1 Active DFGin 6.4283 12.8827 BLAminus -134.66, -177.54 64.98, 72.97 -97.16, 23.35 307.97, 91.21 -67.14, -20.9 in-in in 7.0874 Saltbr-in 2.6649 HRD-in -72.82, -47.43 77.51, -0.14 in-in-na SNCiia in-na ActLoopNT-in 2.9091 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -146.87, 77.74 APE9-dihe-na -62.87, -19.79 APE8-dihe-na -82.22, -0.58 APE8-rot-na 94.17 APE67-dihe-na -46.19, -41.2 -76.57, -19.76 APE12-dist-na 15.9071 APE11-dist-na 14.1985 APE10-dist-na 13.7216 APE9-dist-na 14.143 None None None XRAY 2.4 0.232 0.266 b 717.0 684.0 0 20 20 0 [[351, 591]] 1.0 6m12 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DSYA A5H025 22 727 743.0 25A:801,HFX:802 Allosteric,Type1 Active DFGin 6.3648 12.6394 BLAminus -156.68, 178.51 65.37, 71.2 -91.96, 12.73 308.43, 104.25 -60.03, -19.5 in-in in 6.9676 Saltbr-in 2.5694 HRD-in -70.27, -45.14 82.71, -11.04 in-in-na SNCiia in-na ActLoopNT-in 2.983 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -150.7, 86.73 APE9-dihe-na -68.82, -12.24 APE8-dihe-na -69.19, -29.11 APE8-rot-na 207.72 APE67-dihe-na -51.8, -38.23 -70.51, -7.54 APE12-dist-na 15.9829 APE11-dist-na 12.9322 APE10-dist-na 13.2312 APE9-dist-na 13.6044 None None None XRAY 2.651 0.202 0.27 a 717.0 672.0 3 20 20 0 [[351, 591]] 1.0 7dsy Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DSYB A5H025 23 727 743.0 25A:801,HFX:802 Allosteric,Type1 Active DFGin 6.3065 12.9158 BLAminus -158.23, 179.73 62.1, 71.23 -91.65, 12.04 307.43, 99.93 -57.87, -17.27 in-in in 6.7941 Saltbr-in 2.4896 HRD-in -71.42, -43.63 81.92, -11.0 in-in-na SNCiia in-na ActLoopNT-in 3.0011 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.09, 87.35 APE9-dihe-na -73.69, -17.84 APE8-dihe-na -73.8, -12.56 APE8-rot-na 196.19 APE67-dihe-na -52.88, -37.27 -73.45, -12.55 APE12-dist-na 16.1687 APE11-dist-na 14.3607 APE10-dist-na 13.8994 APE9-dist-na 14.2106 None None None XRAY 2.651 0.202 0.27 b 717.0 676.0 0 20 20 0 [[351, 591]] 1.0 7dsy Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DTSA A5H025 22 727 743.0 25A:801,27K:802 Allosteric,Type1 Active DFGin 6.6552 12.9247 BLAminus -148.34, 179.12 65.68, 80.38 -106.63, 23.42 298.06, 98.88 -80.71, -8.51 in-in in 6.4493 Saltbr-in 2.3127 HRD-in -63.53, -50.62 81.13, -2.15 in-in-na SNCiia in-na ActLoopNT-in 2.9713 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -165.46, 81.85 APE9-dihe-na -65.92, -7.62 APE8-dihe-na -84.25, -14.41 APE8-rot-na 291.14 APE67-dihe-na -54.25, -24.06 -78.48, -15.14 APE12-dist-na 15.7677 APE11-dist-na 13.0654 APE10-dist-na 12.9645 APE9-dist-na 13.543 None None None XRAY 2.63 0.196 0.27 a 717.0 672.0 3 20 20 0 [[351, 591]] 1.0 7dts Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DTSB A5H025 23 727 743.0 25A:801,27K:802 Allosteric,Type1 Active DFGin 6.5533 13.2411 BLAminus -145.93, 175.15 61.55, 78.48 -103.09, 22.61 293.27, 94.75 -77.84, -6.27 in-in in 6.9474 Saltbr-in 2.6829 HRD-in -64.98, -50.53 80.55, -0.96 in-in-na SNCiia in-na ActLoopNT-in 2.9549 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -158.58, 77.52 APE9-dihe-na -70.48, -13.04 APE8-dihe-na -84.11, -10.75 APE8-rot-na 94.63 APE67-dihe-na -55.5, -29.08 -69.2, -15.42 APE12-dist-na 16.2702 APE11-dist-na 15.041 APE10-dist-na 13.8252 APE9-dist-na 14.3828 None None None XRAY 2.63 0.196 0.27 b 717.0 680.0 0 20 20 0 [[351, 591]] 1.0 7dts Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7ELWA A5H025 22 727 743.0 25L:801,MYC:802 Allosteric,Type1 Active DFGin 6.2581 12.9469 BLAminus -153.79, -174.23 60.66, 68.52 -94.97, 28.83 308.9, 99.5 -68.4, -12.94 in-in in 7.0012 Saltbr-in 2.9631 HRD-in -74.89, -41.96 71.19, -6.64 in-in-na SNCiia in-na ActLoopNT-in 2.9425 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -146.44, 93.35 APE9-dihe-na -63.87, -29.1 APE8-dihe-na -87.54, -0.02 APE8-rot-na 73.52 APE67-dihe-na -61.96, -31.77 -70.57, -10.67 APE12-dist-na 15.7769 APE11-dist-na 13.2496 APE10-dist-na 13.412 APE9-dist-na 14.3694 None None None XRAY 3.55 0.242 0.28 a 717.0 675.0 3 20 20 0 [[351, 591]] 1.0 7elw Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7ELWB A5H025 23 727 743.0 25L:801,MYC:802 Allosteric,Type1 Active DFGin 6.5368 12.8396 BLAminus -152.65, -174.7 61.03, 66.79 -95.49, 28.52 309.91, 99.58 -69.43, -12.81 in-in in 6.9659 Saltbr-in 3.2899 HRD-in -74.75, -43.92 70.87, -7.87 in-in-na SNCiia in-na ActLoopNT-in 3.178 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.43, 89.98 APE9-dihe-na -68.41, -29.98 APE8-dihe-na -86.8, 0.05 APE8-rot-na 74.52 APE67-dihe-na -61.58, -34.35 -70.52, -9.29 APE12-dist-na 15.9689 APE11-dist-na 13.976 APE10-dist-na 13.5011 APE9-dist-na 14.3037 None None None XRAY 3.55 0.242 0.28 b 717.0 676.0 0 20 20 0 [[351, 591]] 1.0 7elw Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M12A A5H025 22 727 743.0 J60:801,25L:802 Type1,Allosteric Active DFGin 6.4967 12.8768 BLAminus -133.94, -179.84 67.9, 72.88 -97.74, 23.44 305.42, 86.48 -66.53, -24.1 in-in in 7.076 Saltbr-in 2.6931 HRD-in -72.57, -46.48 77.1, -3.28 in-in-na SNCiia in-na ActLoopNT-in 2.9084 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -157.27, 90.27 APE9-dihe-na -58.08, -28.85 APE8-dihe-na -81.63, -1.5 APE8-rot-na 107.77 APE67-dihe-na -49.85, -40.27 -77.78, -15.43 APE12-dist-na 15.455 APE11-dist-na 12.2934 APE10-dist-na 13.1402 APE9-dist-na 13.611 None None None XRAY 2.4 0.232 0.266 a 717.0 681.0 0 20 20 0 [[351, 591]] 1.0 6m12 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M13A A5H025 22 727 743.0 BWC:801,25L:802 Type1,Allosteric Active DFGin 6.4242 12.8388 BLAminus -135.35, -178.66 68.41, 71.1 -98.45, 29.64 306.14, 96.19 -74.22, -24.16 in-in in 7.0394 Saltbr-in 2.7165 HRD-in -75.96, -45.1 77.37, -0.13 in-in-na SNCiia in-na ActLoopNT-in 2.9139 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -163.33, 84.25 APE9-dihe-na -58.44, -18.65 APE8-dihe-na -78.89, -11.57 APE8-rot-na 255.69 APE67-dihe-na -59.21, -34.9 -83.11, -1.84 APE12-dist-na 15.8383 APE11-dist-na 12.4189 APE10-dist-na 13.0397 APE9-dist-na 13.6407 None None None XRAY 2.56 0.234 0.286 a 717.0 681.0 0 20 20 0 [[351, 591]] 1.0 6m13 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M13B A5H025 23 729 743.0 BWC:901,25L:902 Type1,Allosteric Active DFGin 6.398 13.006 BLAminus -136.47, -176.77 66.26, 71.43 -102.67, 33.53 310.5, 91.93 -72.65, -23.73 in-in in 7.0714 Saltbr-in 3.2849 HRD-in -73.55, -46.93 74.86, 3.45 in-in-na SNCiia in-na ActLoopNT-in 2.9076 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -160.4, 78.51 APE9-dihe-na -59.88, -15.71 APE8-dihe-na -78.79, -9.96 APE8-rot-na 197.91 APE67-dihe-na -68.99, -22.82 -85.86, -3.29 APE12-dist-na 15.9189 APE11-dist-na 13.6837 APE10-dist-na 13.9736 APE9-dist-na 14.245 None None None XRAY 2.56 0.234 0.286 b 717.0 688.0 2 20 20 0 [[351, 591]] 1.0 6m13 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PA A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5106 12.9603 ABAminus -131.33, -33.02 -113.57, 101.31 -107.24, 17.35 306.62, 95.87 -64.46, -18.71 in-in in 7.0246 Saltbr-in 2.5592 HRD-in -60.39, -60.51 77.09, -8.47 in-in-na SNCiia in-na ActLoopNT-in 2.8318 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.96, 83.14 APE9-dihe-na -58.16, -26.45 APE8-dihe-na -61.31, -25.89 APE8-rot-na 201.37 APE67-dihe-na -54.23, -32.66 -72.61, -17.63 APE12-dist-na 15.865 APE11-dist-na 12.9589 APE10-dist-na 13.1315 APE9-dist-na 13.8672 None None None XRAY 2.5 0.198 0.231 A 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PB A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5583 12.9326 ABAminus -131.25, -34.01 -112.79, 101.17 -107.11, 16.68 306.49, 96.02 -64.91, -18.59 in-in in 7.0347 Saltbr-in 2.5611 HRD-in -55.77, -50.97 68.09, -3.12 in-in-na SNCiia in-na ActLoopNT-in 2.8687 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.24, 83.66 APE9-dihe-na -56.74, -27.11 APE8-dihe-na -62.19, -25.6 APE8-rot-na 202.01 APE67-dihe-na -55.19, -32.83 -72.11, -17.43 APE12-dist-na 15.8375 APE11-dist-na 12.884 APE10-dist-na 13.1268 APE9-dist-na 13.6898 None None None XRAY 2.5 0.198 0.231 B 717.0 671.0 3 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PC A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5736 12.9509 ABAminus -131.64, -33.31 -113.88, 102.15 -109.17, 16.76 306.25, 95.79 -63.9, -18.81 in-in in 7.0356 Saltbr-in 2.5563 HRD-in -57.15, -62.34 78.43, -4.0 in-in-na SNCiia in-na ActLoopNT-in 2.8402 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.78, 82.89 APE9-dihe-na -56.9, -26.71 APE8-dihe-na -61.49, -26.14 APE8-rot-na 201.42 APE67-dihe-na -54.45, -32.57 -72.46, -17.58 APE12-dist-na 15.8741 APE11-dist-na 12.9723 APE10-dist-na 13.1218 APE9-dist-na 13.7065 None None None XRAY 2.5 0.198 0.231 C 717.0 673.0 4 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PD A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5223 12.9182 ABAminus -132.11, -32.85 -113.92, 101.55 -106.16, 16.67 306.88, 96.47 -66.56, -17.9 in-in in 7.0247 Saltbr-in 2.5581 HRD-in -66.2, -51.02 69.27, -3.45 in-in-na SNCiia in-na ActLoopNT-in 2.837 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -143.98, 84.27 APE9-dihe-na -56.61, -27.19 APE8-dihe-na -61.86, -25.69 APE8-rot-na 201.6 APE67-dihe-na -54.63, -32.79 -72.23, -18.0 APE12-dist-na 15.8126 APE11-dist-na 12.7951 APE10-dist-na 13.0985 APE9-dist-na 13.6043 None None None XRAY 2.5 0.198 0.231 D 717.0 668.0 5 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OA A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.415 12.8368 ABAminus -148.47, 26.82 -145.52, 134.71 -120.69, 16.23 310.34, 88.99 -61.59, -24.16 in-in in 7.0682 Saltbr-in 2.8216 HRD-out -97.79, 99.85 -78.57, -3.81 in-in-na SNCiia in-na ActLoopNT-in 2.7381 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.14, 77.41 APE9-dihe-na -59.68, -19.27 APE8-dihe-na -48.91, -33.61 APE8-rot-na 191.15 APE67-dihe-na -60.85, -32.6 -79.11, -10.43 APE12-dist-na 15.525 APE11-dist-na 13.5947 APE10-dist-na 13.8421 APE9-dist-na 13.6566 None None None XRAY 3.27 0.232 0.289 A 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OB A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3427 12.7181 ABAminus -147.22, -1.25 -120.21, 106.2 -115.06, 15.52 309.62, 87.7 -60.83, -24.09 in-in in 7.0549 Saltbr-in 2.8227 HRD-out -100.09, 100.84 -77.36, -3.63 in-in-na SNCiia in-na ActLoopNT-in 2.7475 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -141.71, 77.42 APE9-dihe-na -55.97, -21.55 APE8-dihe-na -50.09, -32.22 APE8-rot-na 189.45 APE67-dihe-na -60.53, -32.3 -78.38, -11.74 APE12-dist-na 15.5105 APE11-dist-na 13.3767 APE10-dist-na 13.6734 APE9-dist-na 13.5594 None None None XRAY 3.27 0.232 0.289 B 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OC A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3997 12.7547 ABAminus -149.17, 1.09 -120.22, 107.65 -115.01, 16.0 310.49, 88.57 -60.55, -25.02 in-in in 7.0425 Saltbr-in 2.8406 HRD-out -98.7, 100.33 -77.19, -4.92 in-in-na SNCiia in-na ActLoopNT-in 2.7347 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.93, 76.7 APE9-dihe-na -55.87, -20.93 APE8-dihe-na -49.62, -33.53 APE8-rot-na 190.44 APE67-dihe-na -60.77, -33.33 -77.79, -11.63 APE12-dist-na 15.5163 APE11-dist-na 13.4652 APE10-dist-na 13.7679 APE9-dist-na 13.6486 None None None XRAY 3.27 0.232 0.289 C 717.0 671.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OD A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3738 12.7586 ABAminus -149.4, 0.12 -121.2, 106.45 -114.68, 15.77 309.53, 88.04 -61.04, -24.86 in-in in 7.0308 Saltbr-in 2.8424 HRD-out -98.4, 100.34 -77.37, -4.67 in-in-na SNCiia in-na ActLoopNT-in 2.7336 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.58, 76.86 APE9-dihe-na -55.1, -21.48 APE8-dihe-na -50.82, -32.01 APE8-rot-na 189.04 APE67-dihe-na -61.14, -32.7 -78.2, -11.56 APE12-dist-na 15.4942 APE11-dist-na 13.3908 APE10-dist-na 13.7134 APE9-dist-na 13.6015 None None None XRAY 3.27 0.232 0.289 D 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L

OTHER_RNASEL (2-5A-dependent ribonuclease)

Total number of chains: 20
Active chains: 12
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 60.0% 6M12b
DFGin ABAminus 8 40.0% 4O1PB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RNASEL A5H025_PIG 6M11A A5H025 22 727 743.0 25A:1000,B49:1001 Allosteric,Type1 Active DFGin 6.4775 12.988 BLAminus -155.56, -175.42 53.36, 69.23 -78.35, 0.82 299.16, 87.45 -44.61, -27.7 in-in in 6.9973 Saltbr-in 2.7597 HRD-in -77.65, -46.61 73.81, -8.63 in-in-na SNCiia in-na ActLoopNT-in 2.9186 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -150.91, 91.82 APE9-dihe-na -58.05, -29.31 APE8-dihe-na -85.86, 5.21 APE8-rot-na 81.56 APE67-dihe-na -49.78, -40.92 -78.75, -14.68 APE12-dist-na 15.8012 APE11-dist-na 12.511 APE10-dist-na 13.1969 APE9-dist-na 13.8976 None None None XRAY 2.46 0.223 0.285 a 717.0 681.0 3 20 20 0 [[351, 591]] 1.0 6m11 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M11B A5H025 23 727 743.0 25A:801,B49:802 Allosteric,Type1 Active DFGin 6.4307 12.9157 BLAminus -135.39, -175.08 63.06, 58.49 -90.2, 44.42 312.3, 86.88 -87.38, -12.11 in-in in 7.0656 Saltbr-in 2.7498 HRD-in -74.93, -49.19 77.69, -5.89 in-in-na SNCiia in-na ActLoopNT-in 2.8903 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -145.22, 69.59 APE9-dihe-na -60.88, -23.05 APE8-dihe-na -93.06, -0.03 APE8-rot-na 81.83 APE67-dihe-na -42.69, -43.6 -77.55, -16.15 APE12-dist-na 15.985 APE11-dist-na 13.983 APE10-dist-na 12.943 APE9-dist-na 14.252 None None None XRAY 2.46 0.223 0.285 b 717.0 684.0 0 20 20 0 [[351, 591]] 1.0 6m11 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M12B A5H025 24 726 743.0 25L:801,J60:802 Allosteric,Type1 Active DFGin 6.4283 12.8827 BLAminus -134.66, -177.54 64.98, 72.97 -97.16, 23.35 307.97, 91.21 -67.14, -20.9 in-in in 7.0874 Saltbr-in 2.6649 HRD-in -72.82, -47.43 77.51, -0.14 in-in-na SNCiia in-na ActLoopNT-in 2.9091 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -146.87, 77.74 APE9-dihe-na -62.87, -19.79 APE8-dihe-na -82.22, -0.58 APE8-rot-na 94.17 APE67-dihe-na -46.19, -41.2 -76.57, -19.76 APE12-dist-na 15.9071 APE11-dist-na 14.1985 APE10-dist-na 13.7216 APE9-dist-na 14.143 None None None XRAY 2.4 0.232 0.266 b 717.0 684.0 0 20 20 0 [[351, 591]] 1.0 6m12 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DSYA A5H025 22 727 743.0 25A:801,HFX:802 Allosteric,Type1 Active DFGin 6.3648 12.6394 BLAminus -156.68, 178.51 65.37, 71.2 -91.96, 12.73 308.43, 104.25 -60.03, -19.5 in-in in 6.9676 Saltbr-in 2.5694 HRD-in -70.27, -45.14 82.71, -11.04 in-in-na SNCiia in-na ActLoopNT-in 2.983 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -150.7, 86.73 APE9-dihe-na -68.82, -12.24 APE8-dihe-na -69.19, -29.11 APE8-rot-na 207.72 APE67-dihe-na -51.8, -38.23 -70.51, -7.54 APE12-dist-na 15.9829 APE11-dist-na 12.9322 APE10-dist-na 13.2312 APE9-dist-na 13.6044 None None None XRAY 2.651 0.202 0.27 a 717.0 672.0 3 20 20 0 [[351, 591]] 1.0 7dsy Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DSYB A5H025 23 727 743.0 25A:801,HFX:802 Allosteric,Type1 Active DFGin 6.3065 12.9158 BLAminus -158.23, 179.73 62.1, 71.23 -91.65, 12.04 307.43, 99.93 -57.87, -17.27 in-in in 6.7941 Saltbr-in 2.4896 HRD-in -71.42, -43.63 81.92, -11.0 in-in-na SNCiia in-na ActLoopNT-in 3.0011 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.09, 87.35 APE9-dihe-na -73.69, -17.84 APE8-dihe-na -73.8, -12.56 APE8-rot-na 196.19 APE67-dihe-na -52.88, -37.27 -73.45, -12.55 APE12-dist-na 16.1687 APE11-dist-na 14.3607 APE10-dist-na 13.8994 APE9-dist-na 14.2106 None None None XRAY 2.651 0.202 0.27 b 717.0 676.0 0 20 20 0 [[351, 591]] 1.0 7dsy Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DTSA A5H025 22 727 743.0 25A:801,27K:802 Allosteric,Type1 Active DFGin 6.6552 12.9247 BLAminus -148.34, 179.12 65.68, 80.38 -106.63, 23.42 298.06, 98.88 -80.71, -8.51 in-in in 6.4493 Saltbr-in 2.3127 HRD-in -63.53, -50.62 81.13, -2.15 in-in-na SNCiia in-na ActLoopNT-in 2.9713 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -165.46, 81.85 APE9-dihe-na -65.92, -7.62 APE8-dihe-na -84.25, -14.41 APE8-rot-na 291.14 APE67-dihe-na -54.25, -24.06 -78.48, -15.14 APE12-dist-na 15.7677 APE11-dist-na 13.0654 APE10-dist-na 12.9645 APE9-dist-na 13.543 None None None XRAY 2.63 0.196 0.27 a 717.0 672.0 3 20 20 0 [[351, 591]] 1.0 7dts Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7DTSB A5H025 23 727 743.0 25A:801,27K:802 Allosteric,Type1 Active DFGin 6.5533 13.2411 BLAminus -145.93, 175.15 61.55, 78.48 -103.09, 22.61 293.27, 94.75 -77.84, -6.27 in-in in 6.9474 Saltbr-in 2.6829 HRD-in -64.98, -50.53 80.55, -0.96 in-in-na SNCiia in-na ActLoopNT-in 2.9549 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -158.58, 77.52 APE9-dihe-na -70.48, -13.04 APE8-dihe-na -84.11, -10.75 APE8-rot-na 94.63 APE67-dihe-na -55.5, -29.08 -69.2, -15.42 APE12-dist-na 16.2702 APE11-dist-na 15.041 APE10-dist-na 13.8252 APE9-dist-na 14.3828 None None None XRAY 2.63 0.196 0.27 b 717.0 680.0 0 20 20 0 [[351, 591]] 1.0 7dts Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7ELWA A5H025 22 727 743.0 25L:801,MYC:802 Allosteric,Type1 Active DFGin 6.2581 12.9469 BLAminus -153.79, -174.23 60.66, 68.52 -94.97, 28.83 308.9, 99.5 -68.4, -12.94 in-in in 7.0012 Saltbr-in 2.9631 HRD-in -74.89, -41.96 71.19, -6.64 in-in-na SNCiia in-na ActLoopNT-in 2.9425 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -146.44, 93.35 APE9-dihe-na -63.87, -29.1 APE8-dihe-na -87.54, -0.02 APE8-rot-na 73.52 APE67-dihe-na -61.96, -31.77 -70.57, -10.67 APE12-dist-na 15.7769 APE11-dist-na 13.2496 APE10-dist-na 13.412 APE9-dist-na 14.3694 None None None XRAY 3.55 0.242 0.28 a 717.0 675.0 3 20 20 0 [[351, 591]] 1.0 7elw Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 7ELWB A5H025 23 727 743.0 25L:801,MYC:802 Allosteric,Type1 Active DFGin 6.5368 12.8396 BLAminus -152.65, -174.7 61.03, 66.79 -95.49, 28.52 309.91, 99.58 -69.43, -12.81 in-in in 6.9659 Saltbr-in 3.2899 HRD-in -74.75, -43.92 70.87, -7.87 in-in-na SNCiia in-na ActLoopNT-in 3.178 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.43, 89.98 APE9-dihe-na -68.41, -29.98 APE8-dihe-na -86.8, 0.05 APE8-rot-na 74.52 APE67-dihe-na -61.58, -34.35 -70.52, -9.29 APE12-dist-na 15.9689 APE11-dist-na 13.976 APE10-dist-na 13.5011 APE9-dist-na 14.3037 None None None XRAY 3.55 0.242 0.28 b 717.0 676.0 0 20 20 0 [[351, 591]] 1.0 7elw Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M12A A5H025 22 727 743.0 J60:801,25L:802 Type1,Allosteric Active DFGin 6.4967 12.8768 BLAminus -133.94, -179.84 67.9, 72.88 -97.74, 23.44 305.42, 86.48 -66.53, -24.1 in-in in 7.076 Saltbr-in 2.6931 HRD-in -72.57, -46.48 77.1, -3.28 in-in-na SNCiia in-na ActLoopNT-in 2.9084 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -157.27, 90.27 APE9-dihe-na -58.08, -28.85 APE8-dihe-na -81.63, -1.5 APE8-rot-na 107.77 APE67-dihe-na -49.85, -40.27 -77.78, -15.43 APE12-dist-na 15.455 APE11-dist-na 12.2934 APE10-dist-na 13.1402 APE9-dist-na 13.611 None None None XRAY 2.4 0.232 0.266 a 717.0 681.0 0 20 20 0 [[351, 591]] 1.0 6m12 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M13A A5H025 22 727 743.0 BWC:801,25L:802 Type1,Allosteric Active DFGin 6.4242 12.8388 BLAminus -135.35, -178.66 68.41, 71.1 -98.45, 29.64 306.14, 96.19 -74.22, -24.16 in-in in 7.0394 Saltbr-in 2.7165 HRD-in -75.96, -45.1 77.37, -0.13 in-in-na SNCiia in-na ActLoopNT-in 2.9139 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -163.33, 84.25 APE9-dihe-na -58.44, -18.65 APE8-dihe-na -78.89, -11.57 APE8-rot-na 255.69 APE67-dihe-na -59.21, -34.9 -83.11, -1.84 APE12-dist-na 15.8383 APE11-dist-na 12.4189 APE10-dist-na 13.0397 APE9-dist-na 13.6407 None None None XRAY 2.56 0.234 0.286 a 717.0 681.0 0 20 20 0 [[351, 591]] 1.0 6m13 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 6M13B A5H025 23 729 743.0 BWC:901,25L:902 Type1,Allosteric Active DFGin 6.398 13.006 BLAminus -136.47, -176.77 66.26, 71.43 -102.67, 33.53 310.5, 91.93 -72.65, -23.73 in-in in 7.0714 Saltbr-in 3.2849 HRD-in -73.55, -46.93 74.86, 3.45 in-in-na SNCiia in-na ActLoopNT-in 2.9076 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -160.4, 78.51 APE9-dihe-na -59.88, -15.71 APE8-dihe-na -78.79, -9.96 APE8-rot-na 197.91 APE67-dihe-na -68.99, -22.82 -85.86, -3.29 APE12-dist-na 15.9189 APE11-dist-na 13.6837 APE10-dist-na 13.9736 APE9-dist-na 14.245 None None None XRAY 2.56 0.234 0.286 b 717.0 688.0 2 20 20 0 [[351, 591]] 1.0 6m13 Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PA A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5106 12.9603 ABAminus -131.33, -33.02 -113.57, 101.31 -107.24, 17.35 306.62, 95.87 -64.46, -18.71 in-in in 7.0246 Saltbr-in 2.5592 HRD-in -60.39, -60.51 77.09, -8.47 in-in-na SNCiia in-na ActLoopNT-in 2.8318 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.96, 83.14 APE9-dihe-na -58.16, -26.45 APE8-dihe-na -61.31, -25.89 APE8-rot-na 201.37 APE67-dihe-na -54.23, -32.66 -72.61, -17.63 APE12-dist-na 15.865 APE11-dist-na 12.9589 APE10-dist-na 13.1315 APE9-dist-na 13.8672 None None None XRAY 2.5 0.198 0.231 A 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PB A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5583 12.9326 ABAminus -131.25, -34.01 -112.79, 101.17 -107.11, 16.68 306.49, 96.02 -64.91, -18.59 in-in in 7.0347 Saltbr-in 2.5611 HRD-in -55.77, -50.97 68.09, -3.12 in-in-na SNCiia in-na ActLoopNT-in 2.8687 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -144.24, 83.66 APE9-dihe-na -56.74, -27.11 APE8-dihe-na -62.19, -25.6 APE8-rot-na 202.01 APE67-dihe-na -55.19, -32.83 -72.11, -17.43 APE12-dist-na 15.8375 APE11-dist-na 12.884 APE10-dist-na 13.1268 APE9-dist-na 13.6898 None None None XRAY 2.5 0.198 0.231 B 717.0 671.0 3 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PC A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5736 12.9509 ABAminus -131.64, -33.31 -113.88, 102.15 -109.17, 16.76 306.25, 95.79 -63.9, -18.81 in-in in 7.0356 Saltbr-in 2.5563 HRD-in -57.15, -62.34 78.43, -4.0 in-in-na SNCiia in-na ActLoopNT-in 2.8402 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.78, 82.89 APE9-dihe-na -56.9, -26.71 APE8-dihe-na -61.49, -26.14 APE8-rot-na 201.42 APE67-dihe-na -54.45, -32.57 -72.46, -17.58 APE12-dist-na 15.8741 APE11-dist-na 12.9723 APE10-dist-na 13.1218 APE9-dist-na 13.7065 None None None XRAY 2.5 0.198 0.231 C 717.0 673.0 4 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1PD A5H025 22 729 743.0 ANP:901,25L:904 ATPlike,Allosteric Inactive DFGin 6.5223 12.9182 ABAminus -132.11, -32.85 -113.92, 101.55 -106.16, 16.67 306.88, 96.47 -66.56, -17.9 in-in in 7.0247 Saltbr-in 2.5581 HRD-in -66.2, -51.02 69.27, -3.45 in-in-na SNCiia in-na ActLoopNT-in 2.837 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -143.98, 84.27 APE9-dihe-na -56.61, -27.19 APE8-dihe-na -61.86, -25.69 APE8-rot-na 201.6 APE67-dihe-na -54.63, -32.79 -72.23, -18.0 APE12-dist-na 15.8126 APE11-dist-na 12.7951 APE10-dist-na 13.0985 APE9-dist-na 13.6043 None None None XRAY 2.5 0.198 0.231 D 717.0 668.0 5 20 20 0 [[351, 591]] 1.0 4o1p Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OA A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.415 12.8368 ABAminus -148.47, 26.82 -145.52, 134.71 -120.69, 16.23 310.34, 88.99 -61.59, -24.16 in-in in 7.0682 Saltbr-in 2.8216 HRD-out -97.79, 99.85 -78.57, -3.81 in-in-na SNCiia in-na ActLoopNT-in 2.7381 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.14, 77.41 APE9-dihe-na -59.68, -19.27 APE8-dihe-na -48.91, -33.61 APE8-rot-na 191.15 APE67-dihe-na -60.85, -32.6 -79.11, -10.43 APE12-dist-na 15.525 APE11-dist-na 13.5947 APE10-dist-na 13.8421 APE9-dist-na 13.6566 None None None XRAY 3.27 0.232 0.289 A 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OB A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3427 12.7181 ABAminus -147.22, -1.25 -120.21, 106.2 -115.06, 15.52 309.62, 87.7 -60.83, -24.09 in-in in 7.0549 Saltbr-in 2.8227 HRD-out -100.09, 100.84 -77.36, -3.63 in-in-na SNCiia in-na ActLoopNT-in 2.7475 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -141.71, 77.42 APE9-dihe-na -55.97, -21.55 APE8-dihe-na -50.09, -32.22 APE8-rot-na 189.45 APE67-dihe-na -60.53, -32.3 -78.38, -11.74 APE12-dist-na 15.5105 APE11-dist-na 13.3767 APE10-dist-na 13.6734 APE9-dist-na 13.5594 None None None XRAY 3.27 0.232 0.289 B 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OC A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3997 12.7547 ABAminus -149.17, 1.09 -120.22, 107.65 -115.01, 16.0 310.49, 88.57 -60.55, -25.02 in-in in 7.0425 Saltbr-in 2.8406 HRD-out -98.7, 100.33 -77.19, -4.92 in-in-na SNCiia in-na ActLoopNT-in 2.7347 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.93, 76.7 APE9-dihe-na -55.87, -20.93 APE8-dihe-na -49.62, -33.53 APE8-rot-na 190.44 APE67-dihe-na -60.77, -33.33 -77.79, -11.63 APE12-dist-na 15.5163 APE11-dist-na 13.4652 APE10-dist-na 13.7679 APE9-dist-na 13.6486 None None None XRAY 3.27 0.232 0.289 C 717.0 671.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L
RNASEL A5H025_PIG 4O1OD A5H025 22 729 743.0 25L:1000 Allosteric Inactive DFGin 6.3738 12.7586 ABAminus -149.4, 0.12 -121.2, 106.45 -114.68, 15.77 309.53, 88.04 -61.04, -24.86 in-in in 7.0308 Saltbr-in 2.8424 HRD-out -98.4, 100.34 -77.37, -4.67 in-in-na SNCiia in-na ActLoopNT-in 2.7336 ActLoopCT-na noAPE APEdihe_aaaaa APEdist_aaaa APE10-dihe-na -142.58, 76.86 APE9-dihe-na -55.1, -21.48 APE8-dihe-na -50.82, -32.01 APE8-rot-na 189.04 APE67-dihe-na -61.14, -32.7 -78.2, -11.56 APE12-dist-na 15.4942 APE11-dist-na 13.3908 APE10-dist-na 13.7134 APE9-dist-na 13.6015 None None None XRAY 3.27 0.232 0.289 D 717.0 672.0 4 20 20 0 [[351, 591]] 1.0 4o1o Sus scrofa OTHER_RNASEL_PIG RNASEL 2.2e-128 433.7 1.0 242.0 242.0 499 500 501 503 505 390 402 406 479 481 480 482.0 517 519 514 513 512 511 510 509 508 433 Ribonuclease L