NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 2
Active chains: 2
Uniprot: NEK8_HUMAN
Kinase Domain Residues: 4 - 258
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q86SG6-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK8 AF-Q86SG6-K1A Q86SG6 1 266 692.0 No_ligand No_ligand Active DFGin 6.66 14.4458 BLAminus -136.07, -168.82 55.05, 71.46 -87.51, 18.24 290.14, 85.78 -61.37, -26.93 in-in in 8.5364 Saltbr-in 2.7088 HRD-in -72.98, -47.67 64.05, 5.86 in-in-in SNCiii in-in ActLoopNT-in 2.8316 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.16, 163.6 APE9-dihe-na 112.34, 168.42 APE8-dihe-in -76.56, 127.97 APE8-rot-in 300.8 APE67-dihe-in -84.65, -3.72 -53.15, -30.23 APE12-dist-in 8.9917 APE11-dist-in 12.0506 APE10-dist-in 6.1663 APE9-dist-in 3.4485 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 27 27 0 [[4, 258]] 1.0 AF-Q86SG6-K1 NEK_NEK8_HUMAN NEK 4.1e-106 360.1 1.0 256.0 256.0 146 147 148 150 152 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek8
NEK8 AF-Q86SG6-K3A Q86SG6 1 266 692.0 No_ligand No_ligand Active DFGin 6.6522 14.5167 BLAminus -135.33, -169.96 53.66, 69.39 -83.36, 13.97 290.78, 87.8 -59.2, -29.65 in-in in 8.2348 Saltbr-in 2.8222 HRD-in -75.68, -44.84 66.04, -1.22 in-in-in SNCiii in-in ActLoopNT-in 2.8328 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.94, 162.29 APE9-dihe-na 112.72, 174.36 APE8-dihe-in -79.41, 122.63 APE8-rot-in 299.52 APE67-dihe-in -75.99, -8.33 -52.77, -31.6 APE12-dist-in 9.1579 APE11-dist-in 12.0505 APE10-dist-in 6.2166 APE9-dist-in 3.3018 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 27 27 0 [[4, 258]] 1.0 AF-Q86SG6-K3 NEK_NEK8_HUMAN NEK 4.1e-106 360.1 1.0 256.0 256.0 146 147 148 150 152 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek8

NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q86SG6-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK8 NEK8_HUMAN AF-Q86SG6-K1A Q86SG6 1 266 692.0 No_ligand No_ligand Active DFGin 6.66 14.4458 BLAminus -136.07, -168.82 55.05, 71.46 -87.51, 18.24 290.14, 85.78 -61.37, -26.93 in-in in 8.5364 Saltbr-in 2.7088 HRD-in -72.98, -47.67 64.05, 5.86 in-in-in SNCiii in-in ActLoopNT-in 2.8316 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.16, 163.6 APE9-dihe-na 112.34, 168.42 APE8-dihe-in -76.56, 127.97 APE8-rot-in 300.8 APE67-dihe-in -84.65, -3.72 -53.15, -30.23 APE12-dist-in 8.9917 APE11-dist-in 12.0506 APE10-dist-in 6.1663 APE9-dist-in 3.4485 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 27 27 0 [[4, 258]] 1.0 AF-Q86SG6-K1 Homo sapiens NEK_NEK8_HUMAN NEK 4.1e-106 360.1 1.0 256.0 256.0 146 147 148 150 152 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek8
NEK8 NEK8_HUMAN AF-Q86SG6-K3A Q86SG6 1 266 692.0 No_ligand No_ligand Active DFGin 6.6522 14.5167 BLAminus -135.33, -169.96 53.66, 69.39 -83.36, 13.97 290.78, 87.8 -59.2, -29.65 in-in in 8.2348 Saltbr-in 2.8222 HRD-in -75.68, -44.84 66.04, -1.22 in-in-in SNCiii in-in ActLoopNT-in 2.8328 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.94, 162.29 APE9-dihe-na 112.72, 174.36 APE8-dihe-in -79.41, 122.63 APE8-rot-in 299.52 APE67-dihe-in -75.99, -8.33 -52.77, -31.6 APE12-dist-in 9.1579 APE11-dist-in 12.0505 APE10-dist-in 6.2166 APE9-dist-in 3.3018 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 27 27 0 [[4, 258]] 1.0 AF-Q86SG6-K3 Homo sapiens NEK_NEK8_HUMAN NEK 4.1e-106 360.1 1.0 256.0 256.0 146 147 148 150 152 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek8

NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name