TYR_MUSK (Muscle, skeletal receptor tyrosine-protein kinase)

Total number of chains: 2
Active chains: 2
Uniprot: MUSK_HUMAN
Kinase Domain Residues: 575 - 858
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O15146-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O15146-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase
AF-O15146-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase

TYR_MUSK (Muscle, skeletal receptor tyrosine-protein kinase)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-O15146-K1A
DFGinter None 1 33.3% 1LUFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MUSK_HUMAN AF-O15146-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase Homo sapiens
MUSK_HUMAN AF-O15146-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase Homo sapiens
MUSK_RAT 1LUFA 2.05 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 560 - 860 0 None None Muscle, skeletal receptor tyrosine protein kinase Rattus norvegicus

TYR_MUSK (Muscle, skeletal receptor tyrosine-protein kinase)

Total number of chains: 1
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 1 100.0% 1LUFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MUSK_RAT 1LUFA 2.05 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 560 - 860 0 None None Muscle, skeletal receptor tyrosine protein kinase Rattus norvegicus