AGC_MASTL (Serine/threonine-protein kinase greatwall)

Total number of chains: 5
Active chains: 2
Uniprot: GWL_HUMAN
Kinase Domain Residues: 35 - 835
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% AF-Q96GX5-K1A
DFGin BLAplus 1 20.0% 5LOHA
None None 1 20.0% 5LOHB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MASTL AF-Q96GX5-K1A Q96GX5 27 843 879.0 No_ligand No_ligand Active DFGin 6.5113 14.2493 BLAminus -136.98, 175.5 52.45, 59.28 -63.96, 15.13 300.56, 93.34 -53.91, -47.49 in-in in 8.7756 Saltbr-in 2.6415 HRD-in -73.64, -43.72 60.71, -18.09 in-in-in SNCiii in-in ActLoopNT-in 2.8738 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.26, 121.64 APE9-dihe-na 143.48, 174.34 APE8-dihe-in -74.8, 126.47 APE8-rot-in 296.06 APE67-dihe-in -71.28, -23.69 -46.57, -43.27 APE12-dist-in 11.4561 APE11-dist-in 12.0476 APE10-dist-in 6.3558 APE9-dist-in 5.0352 None None None AF2 -1.0 1.0 1.0 A 817.0 817.0 0 575 575 0 [[35, 835]] 1.0 AF-Q96GX5-K1 AGC_MASTL_HUMAN AGC 9.2e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 737 111 Serine/threonine-protein kinase greatwall
MASTL AF-Q96GX5-K3A Q96GX5 27 843 879.0 No_ligand No_ligand Active DFGin 5.8874 14.6504 BLAminus -143.15, -179.72 55.04, 67.18 -81.13, 21.34 288.66, 83.06 -63.08, -28.24 in-in in 8.2376 Saltbr-in 2.6695 HRD-in -73.76, -46.46 67.61, -17.09 in-in-in SNCiii in-in ActLoopNT-in 2.8643 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.57, 127.46 APE9-dihe-na 155.7, -179.82 APE8-dihe-in -89.49, 123.19 APE8-rot-in 308.85 APE67-dihe-in -65.53, -23.25 -48.82, -46.12 APE12-dist-in 11.3556 APE11-dist-in 11.6657 APE10-dist-in 6.3031 APE9-dist-in 5.1284 None None None AF2 -1.0 1.0 1.0 A 817.0 817.0 0 575 575 0 [[35, 835]] 1.0 AF-Q96GX5-K3 AGC_MASTL_HUMAN AGC 9.2e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 737 111 Serine/threonine-protein kinase greatwall
MASTL 8V5HA Q96GX5 29 847 879.0 A1AAE:901 Type1 Inactive DFGin 5.0852 13.2231 BLAminus -135.18, 177.58 58.63, 62.34 -71.68, 109.75 297.2, 74.01 -104.29, 55.4 in-out in 8.5208 Saltbr-out 4.3334 HRD-in -78.07, -52.76 71.88, -16.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 128.94 APE9-dihe-na -93.04, -154.15 APE8-dihe-in -57.55, 116.33 APE8-rot-in 298.94 APE67-dihe-in -56.59, -15.98 -59.72, -38.23 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.6145 APE9-dist-out 6.2318 None None None XRAY 2.74 0.254 0.281 A 343.0 250.0 27 575 556 19 [[35, 835]] 1.0 8v5h AGC_MASTL_HUMAN AGC 8.9e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 -9999 111 Serine/threonine-protein kinase greatwall
MASTL 5LOHA Q96GX5 30 854 879.0 STU:60901 Type1 Inactive DFGin 10.8403 13.5188 BLAplus -154.04, -179.93 62.84, 37.43 -106.51, -23.39 59.72, 80.58 -168.74, -25.48 none-none none 999.0 Saltbr-none 999.0 HRD-in -59.31, -45.76 66.7, 4.42 none-out-out SNCnoo out-out ActLoopNT-out 8.33 ActLoopCT-out nonTYR APEdihe_aanon APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 165.16 APE8-dihe-none -79.14, 999.0 APE8-rot-out 44.79 APE67-dihe-none -72.42, -27.62 999.0, 33.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8912 None None None XRAY 3.1 0.209 0.265 A 341.0 246.0 34 28 13 15 [[35, 835]] 1.0 5loh AGC_MASTL_HUMAN AGC 4e-131 441.8 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 201 196 195 741 740 -9999 -9999 -9999 111 Serine/threonine-protein kinase greatwall
MASTL 5LOHB Q96GX5 30 854 879.0 STU:60901 Type1 Inactive None 999.0 13.3388 None -152.85, -174.25 66.27, 69.27 -150.61, -21.46 41.33, 82.81 -90.34, 22.29 none-none none 999.0 Saltbr-none 999.0 HRD-in -60.11, -44.59 64.53, 4.15 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aannn APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -141.8 APE8-dihe-none -77.31, 999.0 APE8-rot-none 999.0 APE67-dihe-none 49.84, -65.93 999.0, -82.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.7129 None None None XRAY 3.1 0.209 0.265 B 341.0 250.0 30 28 11 17 [[35, 835]] 1.0 5loh AGC_MASTL_HUMAN AGC 4e-131 441.8 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 201 196 195 741 740 -9999 -9999 -9999 111 Serine/threonine-protein kinase greatwall

AGC_MASTL (Serine/threonine-protein kinase greatwall)

Total number of chains: 5
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% AF-Q96GX5-K1A
DFGin BLAplus 1 20.0% 5LOHA
None None 1 20.0% 5LOHB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MASTL GWL_HUMAN AF-Q96GX5-K1A Q96GX5 27 843 879.0 No_ligand No_ligand Active DFGin 6.5113 14.2493 BLAminus -136.98, 175.5 52.45, 59.28 -63.96, 15.13 300.56, 93.34 -53.91, -47.49 in-in in 8.7756 Saltbr-in 2.6415 HRD-in -73.64, -43.72 60.71, -18.09 in-in-in SNCiii in-in ActLoopNT-in 2.8738 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.26, 121.64 APE9-dihe-na 143.48, 174.34 APE8-dihe-in -74.8, 126.47 APE8-rot-in 296.06 APE67-dihe-in -71.28, -23.69 -46.57, -43.27 APE12-dist-in 11.4561 APE11-dist-in 12.0476 APE10-dist-in 6.3558 APE9-dist-in 5.0352 None None None AF2 -1.0 1.0 1.0 A 817.0 817.0 0 575 575 0 [[35, 835]] 1.0 AF-Q96GX5-K1 Homo sapiens AGC_MASTL_HUMAN AGC 9.2e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 737 111 Serine/threonine-protein kinase greatwall
MASTL GWL_HUMAN AF-Q96GX5-K3A Q96GX5 27 843 879.0 No_ligand No_ligand Active DFGin 5.8874 14.6504 BLAminus -143.15, -179.72 55.04, 67.18 -81.13, 21.34 288.66, 83.06 -63.08, -28.24 in-in in 8.2376 Saltbr-in 2.6695 HRD-in -73.76, -46.46 67.61, -17.09 in-in-in SNCiii in-in ActLoopNT-in 2.8643 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.57, 127.46 APE9-dihe-na 155.7, -179.82 APE8-dihe-in -89.49, 123.19 APE8-rot-in 308.85 APE67-dihe-in -65.53, -23.25 -48.82, -46.12 APE12-dist-in 11.3556 APE11-dist-in 11.6657 APE10-dist-in 6.3031 APE9-dist-in 5.1284 None None None AF2 -1.0 1.0 1.0 A 817.0 817.0 0 575 575 0 [[35, 835]] 1.0 AF-Q96GX5-K3 Homo sapiens AGC_MASTL_HUMAN AGC 9.2e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 737 111 Serine/threonine-protein kinase greatwall
MASTL GWL_HUMAN 8V5HA Q96GX5 29 847 879.0 A1AAE:901 Type1 Inactive DFGin 5.0852 13.2231 BLAminus -135.18, 177.58 58.63, 62.34 -71.68, 109.75 297.2, 74.01 -104.29, 55.4 in-out in 8.5208 Saltbr-out 4.3334 HRD-in -78.07, -52.76 71.88, -16.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 128.94 APE9-dihe-na -93.04, -154.15 APE8-dihe-in -57.55, 116.33 APE8-rot-in 298.94 APE67-dihe-in -56.59, -15.98 -59.72, -38.23 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.6145 APE9-dist-out 6.2318 None None None XRAY 2.74 0.254 0.281 A 343.0 250.0 27 575 556 19 [[35, 835]] 1.0 8v5h Homo sapiens AGC_MASTL_HUMAN AGC 8.9e-130 437.3 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 748 743 742 741 740 739 738 -9999 111 Serine/threonine-protein kinase greatwall
MASTL GWL_HUMAN 5LOHA Q96GX5 30 854 879.0 STU:60901 Type1 Inactive DFGin 10.8403 13.5188 BLAplus -154.04, -179.93 62.84, 37.43 -106.51, -23.39 59.72, 80.58 -168.74, -25.48 none-none none 999.0 Saltbr-none 999.0 HRD-in -59.31, -45.76 66.7, 4.42 none-out-out SNCnoo out-out ActLoopNT-out 8.33 ActLoopCT-out nonTYR APEdihe_aanon APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 165.16 APE8-dihe-none -79.14, 999.0 APE8-rot-out 44.79 APE67-dihe-none -72.42, -27.62 999.0, 33.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8912 None None None XRAY 3.1 0.209 0.265 A 341.0 246.0 34 28 13 15 [[35, 835]] 1.0 5loh Homo sapiens AGC_MASTL_HUMAN AGC 4e-131 441.8 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 201 196 195 741 740 -9999 -9999 -9999 111 Serine/threonine-protein kinase greatwall
MASTL GWL_HUMAN 5LOHB Q96GX5 30 854 879.0 STU:60901 Type1 Inactive None 999.0 13.3388 None -152.85, -174.25 66.27, 69.27 -150.61, -21.46 41.33, 82.81 -90.34, 22.29 none-none none 999.0 Saltbr-none 999.0 HRD-in -60.11, -44.59 64.53, 4.15 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aannn APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -141.8 APE8-dihe-none -77.31, 999.0 APE8-rot-none 999.0 APE67-dihe-none 49.84, -65.93 999.0, -82.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.7129 None None None XRAY 3.1 0.209 0.265 B 341.0 250.0 30 28 11 17 [[35, 835]] 1.0 5loh Homo sapiens AGC_MASTL_HUMAN AGC 4e-131 441.8 1.0 260.0 260.0 173 174 175 177 179 62 81 85 153 155 154 156.0 760 201 196 195 741 740 -9999 -9999 -9999 111 Serine/threonine-protein kinase greatwall

AGC_MASTL (Serine/threonine-protein kinase greatwall)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name