STE_MAP4K3 (Mitogen-activated protein kinase kinase kinase kinase 3)

Total number of chains: 3
Active chains: 2
Uniprot: M4K3_HUMAN
Kinase Domain Residues: 16 - 273
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q8IVH8-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q8IVH8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 281 0 None None Mitogen-activated protein kinase kinase kinase kinase 3
AF-Q8IVH8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 281 0 None None Mitogen-activated protein kinase kinase kinase kinase 3
5J5TA 2.85 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 6G2 Type1 13 - 314 0 TPO145 S170A Mitogen-activated protein kinase kinase kinase kinase 3

STE_MAP4K3 (Mitogen-activated protein kinase kinase kinase kinase 3)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q8IVH8-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
M4K3_HUMAN AF-Q8IVH8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 281 0 None None Mitogen-activated protein kinase kinase kinase kinase 3 Homo sapiens
M4K3_HUMAN AF-Q8IVH8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 281 0 None None Mitogen-activated protein kinase kinase kinase kinase 3 Homo sapiens
M4K3_HUMAN 5J5TA 2.85 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 6G2 Type1 13 - 314 0 TPO145 S170A Mitogen-activated protein kinase kinase kinase kinase 3 Homo sapiens

STE_MAP4K3 (Mitogen-activated protein kinase kinase kinase kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism