Hover over column headers for tooltip help
| PDB | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P45985-K1A | 94 | 375 | 399.0 | No_ligand | No_ligand | Active | DFGin | 6.024 | 13.974 | BLAminus | -144.38, 178.82 | 63.15, 66.23 | -90.49, 12.46 | 311.33, 100.8 | -64.94, -20.08 | na-na | na | 7.645 | Saltbr-na | 2.655 | HRD-in | -77.58, -44.7 | 69.19, 5.56 | na-in-in | SNCaii | in-in | ActLoopNT-in | 2.828 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | -76.72, 152.93 | APE9-dihe-na | 95.32, 163.65 | APE8-dihe-in | -74.41, 113.18 | APE8-rot-na | 195.25 | APE67-dihe-in | -63.87, -25.53 | -48.12, -43.55 | APE12-dist-in | 12.52 | APE11-dist-in | 10.176 | APE10-dist-in | 5.251 | APE9-dist-in | 3.388 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 282 | 282 | 0 | 0 | 0 | 0 | [[102, 367]] | 1.0 | AF-P45985-K1 | STE_MAP2K4_HUMAN | STE | 4e-86 | 294.5 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| AF-P45985-K3A | 94 | 375 | 399.0 | No_ligand | No_ligand | Active | DFGin | 6.014 | 13.855 | BLAminus | -145.68, 178.46 | 65.47, 68.56 | -89.98, 4.77 | 304.41, 100.58 | -59.88, -23.06 | na-na | na | 7.914 | Saltbr-na | 2.738 | HRD-in | -79.54, -41.27 | 70.86, 3.15 | na-in-in | SNCaii | in-in | ActLoopNT-in | 2.824 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | -126.15, 138.91 | APE9-dihe-na | 114.31, 163.57 | APE8-dihe-in | -74.18, 105.58 | APE8-rot-na | 193.37 | APE67-dihe-in | -50.19, -39.32 | -41.21, -47.27 | APE12-dist-in | 12.139 | APE11-dist-in | 10.38 | APE10-dist-in | 5.065 | APE9-dist-in | 3.571 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 282 | 282 | 0 | 0 | 0 | 0 | [[102, 367]] | 1.0 | AF-P45985-K3 | STE_MAP2K4_HUMAN | STE | 4e-86 | 294.5 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3ALNA | 83 | 389 | 399.0 | ANP:1 | ATPlike | Inactive | DFGin | 6.517 | 13.393 | BLBplus | -161.78, 169.91 | 72.82, 15.08 | -92.63, 122.04 | 60.81, 71.89 | 121.07, -111.8 | na-na | na | 15.525 | Saltbr-na | 999.0 | HRD-in | -50.15, -58.45 | 86.79, 0.09 | na-out-none | SNCaon | out-none | ActLoopNT-out | 11.094 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | A | 327 | 270 | 37 | 0 | 0 | 20 | [[102, 367]] | 1.0 | 3aln | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3ALNB | 84 | 390 | 399.0 | ANP:1 | ATPlike | Inactive | DFGin | 7.062 | 13.613 | BLBplus | -140.58, 160.03 | 87.63, 22.27 | -95.55, 159.55 | 58.77, 88.3 | 94.56, -147.05 | na-na | na | 15.267 | Saltbr-na | 14.949 | HRD-in | -87.89, -53.1 | 65.57, 1.61 | na-out-none | SNCaon | out-none | ActLoopNT-out | 8.255 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | B | 327 | 263 | 44 | 0 | 0 | 19 | [[102, 367]] | 1.0 | 3aln | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3ALOA | 95 | 389 | 399.0 | ANP:406 | ATPlike | Inactive | DFGin | 6.887 | 13.729 | BLBplus | -112.59, -177.7 | 66.85, 21.6 | -92.73, 167.28 | 50.76, 92.54 | 73.18, -126.21 | na-na | na | 15.89 | Saltbr-na | 16.476 | HRD-in | -52.75, -64.74 | 82.96, 2.2 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 8.257 | ActLoopCT-out | nonTYR | APEdihe_aaoao | APEdist_oooo | APE10-dihe-na | -57.34, 98.51 | APE9-dihe-na | 135.89, -16.86 | APE8-dihe-out | -126.39, -33.94 | APE8-rot-na | 70.02 | APE67-dihe-out | -48.7, -17.03 | -94.49, 137.34 | APE12-dist-out | 18.454 | APE11-dist-out | 19.517 | APE10-dist-out | 20.495 | APE9-dist-out | 23.026 | None | None | None | XRAY | 2.6 | 0.209 | 0.271 | A | 327 | 289 | 6 | 0 | 0 | 0 | [[102, 367]] | 1.0 | 3alo | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 8YP5A | 80 | 392 | 399.0 | 1FM:501 | Type1 | Inactive | DFGin | 7.519 | 13.76 | BLBplus | -152.08, 177.39 | 57.94, 27.43 | -91.01, 160.87 | 50.54, 97.87 | 71.82, -120.11 | na-na | na | 15.697 | Saltbr-na | 16.634 | HRD-in | -46.05, -59.08 | 77.01, 5.2 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 8.488 | ActLoopCT-out | nonTYR | APEdihe_aaoai | APEdist_oooo | APE10-dihe-na | -63.73, -5.16 | APE9-dihe-na | -108.36, -10.27 | APE8-dihe-out | -119.29, -38.77 | APE8-rot-na | 65.49 | APE67-dihe-in | -52.63, -18.08 | -55.59, -49.23 | APE12-dist-out | 18.45 | APE11-dist-out | 19.25 | APE10-dist-out | 20.27 | APE9-dist-out | 23.34 | None | None | None | XRAY | 2.5 | 0.237 | 0.326 | A | 327 | 307 | 6 | 0 | 0 | 0 | [[102, 367]] | 1.0 | 8yp5 | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3ALNC | 100 | 390 | 399.0 | ANP:1 | ATPlike | Inactive | None | 999.0 | 11.66 | None | -139.2, 85.12 | 54.71, 167.37 | -67.61, 999.0 | 74.38, 108.84 | 999.0, 999.0 | na-na | na | 999.0 | Saltbr-na | 999.0 | HRD-none | 999.0, 999.0 | 999.0, 999.0 | na-none-none | SNCann | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | C | 327 | 183 | 108 | 0 | 0 | 25 | [[102, 367]] | 1.0 | 3aln | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3VUTA | 142 | 388 | 399.0 | No_ligand | No_ligand | Inactive | None | 19.33 | 999.0 | None | -103.84, -141.67 | -52.27, 82.0 | -141.23, -92.92 | 288.93, 95.82 | 50.23, -94.03 | na-na | na | 999.0 | Saltbr-na | 999.0 | HRD-out | 96.74, 163.24 | -71.16, -87.6 | na-out-none | SNCaon | out-none | ActLoopNT-out | 11.855 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.5 | 0.335 | 0.407 | A | 327 | 203 | 84 | 0 | 0 | 21 | [[102, 367]] | 1.0 | 3vut | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| 3VUTB | 80 | 373 | 399.0 | No_ligand | No_ligand | Inactive | None | 16.999 | 16.067 | None | -128.53, -156.48 | -160.57, 121.94 | -143.29, 36.02 | 92.02, 110.31 | 89.86, -111.69 | na-na | na | 13.383 | Saltbr-na | 17.306 | HRD-out | 133.41, 100.82 | -144.48, 157.12 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 11.37 | ActLoopCT-out | nonTYR | APEdihe_aannn | APEdist_iooo | APE10-dihe-na | -52.64, -45.0 | APE9-dihe-na | -16.72, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-in | 13.131 | APE11-dist-out | 16.486 | APE10-dist-out | 15.888 | APE9-dist-out | 13.335 | None | None | None | XRAY | 3.5 | 0.335 | 0.407 | B | 327 | 259 | 35 | 0 | 0 | 8 | [[102, 367]] | 1.0 | 3vut | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
Hover over column headers for tooltip help
| SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MP2K4_HUMAN | AF-P45985-K1A | P45985 | 94 | 375 | 399.0 | No_ligand | No_ligand | Active | DFGin | 6.024 | 13.974 | BLAminus | -144.38, 178.82 | 63.15, 66.23 | -90.49, 12.46 | 311.33, 100.8 | -64.94, -20.08 | na-na | na | 7.645 | Saltbr-na | 2.655 | HRD-in | -77.58, -44.7 | 69.19, 5.56 | na-in-in | SNCaii | in-in | ActLoopNT-in | 2.828 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | -76.72, 152.93 | APE9-dihe-na | 95.32, 163.65 | APE8-dihe-in | -74.41, 113.18 | APE8-rot-na | 195.25 | APE67-dihe-in | -63.87, -25.53 | -48.12, -43.55 | APE12-dist-in | 12.52 | APE11-dist-in | 10.176 | APE10-dist-in | 5.251 | APE9-dist-in | 3.388 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 282 | 282 | 0 | 0 | 0 | 0 | [[102, 367]] | 1.0 | AF-P45985-K1 | Homo sapiens | STE_MAP2K4_HUMAN | STE | 4e-86 | 294.5 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | AF-P45985-K3A | P45985 | 94 | 375 | 399.0 | No_ligand | No_ligand | Active | DFGin | 6.014 | 13.855 | BLAminus | -145.68, 178.46 | 65.47, 68.56 | -89.98, 4.77 | 304.41, 100.58 | -59.88, -23.06 | na-na | na | 7.914 | Saltbr-na | 2.738 | HRD-in | -79.54, -41.27 | 70.86, 3.15 | na-in-in | SNCaii | in-in | ActLoopNT-in | 2.824 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | -126.15, 138.91 | APE9-dihe-na | 114.31, 163.57 | APE8-dihe-in | -74.18, 105.58 | APE8-rot-na | 193.37 | APE67-dihe-in | -50.19, -39.32 | -41.21, -47.27 | APE12-dist-in | 12.139 | APE11-dist-in | 10.38 | APE10-dist-in | 5.065 | APE9-dist-in | 3.571 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 282 | 282 | 0 | 0 | 0 | 0 | [[102, 367]] | 1.0 | AF-P45985-K3 | Homo sapiens | STE_MAP2K4_HUMAN | STE | 4e-86 | 294.5 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3ALNA | P45985 | 83 | 389 | 399.0 | ANP:1 | ATPlike | Inactive | DFGin | 6.517 | 13.393 | BLBplus | -161.78, 169.91 | 72.82, 15.08 | -92.63, 122.04 | 60.81, 71.89 | 121.07, -111.8 | na-na | na | 15.525 | Saltbr-na | 999.0 | HRD-in | -50.15, -58.45 | 86.79, 0.09 | na-out-none | SNCaon | out-none | ActLoopNT-out | 11.094 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | A | 327 | 270 | 37 | 0 | 0 | 20 | [[102, 367]] | 1.0 | 3aln | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3ALNB | P45985 | 84 | 390 | 399.0 | ANP:1 | ATPlike | Inactive | DFGin | 7.062 | 13.613 | BLBplus | -140.58, 160.03 | 87.63, 22.27 | -95.55, 159.55 | 58.77, 88.3 | 94.56, -147.05 | na-na | na | 15.267 | Saltbr-na | 14.949 | HRD-in | -87.89, -53.1 | 65.57, 1.61 | na-out-none | SNCaon | out-none | ActLoopNT-out | 8.255 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | B | 327 | 263 | 44 | 0 | 0 | 19 | [[102, 367]] | 1.0 | 3aln | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3ALOA | P45985 | 95 | 389 | 399.0 | ANP:406 | ATPlike | Inactive | DFGin | 6.887 | 13.729 | BLBplus | -112.59, -177.7 | 66.85, 21.6 | -92.73, 167.28 | 50.76, 92.54 | 73.18, -126.21 | na-na | na | 15.89 | Saltbr-na | 16.476 | HRD-in | -52.75, -64.74 | 82.96, 2.2 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 8.257 | ActLoopCT-out | nonTYR | APEdihe_aaoao | APEdist_oooo | APE10-dihe-na | -57.34, 98.51 | APE9-dihe-na | 135.89, -16.86 | APE8-dihe-out | -126.39, -33.94 | APE8-rot-na | 70.02 | APE67-dihe-out | -48.7, -17.03 | -94.49, 137.34 | APE12-dist-out | 18.454 | APE11-dist-out | 19.517 | APE10-dist-out | 20.495 | APE9-dist-out | 23.026 | None | None | None | XRAY | 2.6 | 0.209 | 0.271 | A | 327 | 289 | 6 | 0 | 0 | 0 | [[102, 367]] | 1.0 | 3alo | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 8YP5A | P45985 | 80 | 392 | 399.0 | 1FM:501 | Type1 | Inactive | DFGin | 7.519 | 13.76 | BLBplus | -152.08, 177.39 | 57.94, 27.43 | -91.01, 160.87 | 50.54, 97.87 | 71.82, -120.11 | na-na | na | 15.697 | Saltbr-na | 16.634 | HRD-in | -46.05, -59.08 | 77.01, 5.2 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 8.488 | ActLoopCT-out | nonTYR | APEdihe_aaoai | APEdist_oooo | APE10-dihe-na | -63.73, -5.16 | APE9-dihe-na | -108.36, -10.27 | APE8-dihe-out | -119.29, -38.77 | APE8-rot-na | 65.49 | APE67-dihe-in | -52.63, -18.08 | -55.59, -49.23 | APE12-dist-out | 18.45 | APE11-dist-out | 19.25 | APE10-dist-out | 20.27 | APE9-dist-out | 23.34 | None | None | None | XRAY | 2.5 | 0.237 | 0.326 | A | 327 | 307 | 6 | 0 | 0 | 0 | [[102, 367]] | 1.0 | 8yp5 | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3ALNC | P45985 | 100 | 390 | 399.0 | ANP:1 | ATPlike | Inactive | None | 999.0 | 11.66 | None | -139.2, 85.12 | 54.71, 167.37 | -67.61, 999.0 | 74.38, 108.84 | 999.0, 999.0 | na-na | na | 999.0 | Saltbr-na | 999.0 | HRD-none | 999.0, 999.0 | 999.0, 999.0 | na-none-none | SNCann | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.3 | 0.289 | 0.378 | C | 327 | 183 | 108 | 0 | 0 | 25 | [[102, 367]] | 1.0 | 3aln | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3VUTA | P45985 | 142 | 388 | 399.0 | No_ligand | No_ligand | Inactive | None | 19.33 | 999.0 | None | -103.84, -141.67 | -52.27, 82.0 | -141.23, -92.92 | 288.93, 95.82 | 50.23, -94.03 | na-na | na | 999.0 | Saltbr-na | 999.0 | HRD-out | 96.74, 163.24 | -71.16, -87.6 | na-out-none | SNCaon | out-none | ActLoopNT-out | 11.855 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.5 | 0.335 | 0.407 | A | 327 | 203 | 84 | 0 | 0 | 21 | [[102, 367]] | 1.0 | 3vut | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| MP2K4_HUMAN | 3VUTB | P45985 | 80 | 373 | 399.0 | No_ligand | No_ligand | Inactive | None | 16.999 | 16.067 | None | -128.53, -156.48 | -160.57, 121.94 | -143.29, 36.02 | 92.02, 110.31 | 89.86, -111.69 | na-na | na | 13.383 | Saltbr-na | 17.306 | HRD-out | 133.41, 100.82 | -144.48, 157.12 | na-out-out | SNCaoo | out-out | ActLoopNT-out | 11.37 | ActLoopCT-out | nonTYR | APEdihe_aannn | APEdist_iooo | APE10-dihe-na | -52.64, -45.0 | APE9-dihe-na | -16.72, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-in | 13.131 | APE11-dist-out | 16.486 | APE10-dist-out | 15.888 | APE9-dist-out | 13.335 | None | None | None | XRAY | 3.5 | 0.335 | 0.407 | B | 327 | 259 | 35 | 0 | 0 | 8 | [[102, 367]] | 1.0 | 3vut | Homo sapiens | STE_MAP2K4_HUMAN | STE | 6.8e-86 | 293.8 | 4 | 257 | 254 | 246 | 247 | 248 | 250 | 252 | 131 | 148 | 152 | 226 | 228 | 227 | 229 | 289 | 273 | 268 | 267 | 266 | 265 | 264 | 263 | 262 | 179 | Dual specificity mitogen-activated protein kinase kinase 4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
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