TKL_KSR2 (Kinase suppressor of Ras 2)

Total number of chains: 9
Active chains: 0
Family: TKL
Uniprot: KSR2_HUMAN
Kinase Domain Residues: 666 - 930
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 9 100.0% 7JURB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
2Y4IB 653 931 950.0 ATP:1932 ATPlike Pseudo DFGin 6.039 13.357 BLBplus -163.04, 167.92 56.95, 32.67 -75.07, 155.41 46.1, 92.34 53.05, 51.5 out-none out 15.58 Saltbr-none 999.0 HRD-in -80.25, -38.53 67.56, -67.09 none-out-out SNCnoo out-out ActLoopNT-out 10.43 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -56.45, -137.53 APE9-dihe-na -67.8, 7.84 APE8-dihe-out -54.46, -37.41 APE8-rot-na 170.99 APE67-dihe-in -92.05, 13.42 -60.84, -28.22 APE12-dist-out 17.417 APE11-dist-out 14.576 APE10-dist-out 17.158 APE9-dist-out 12.262 None None None XRAY 3.46 0.233 0.293 B 319 265 14 0 0 10 [[665, 930]] 1.0 2y4i TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JUQB 652 932 950.0 ADP:1001 ATPlike Pseudo DFGin 5.723 13.43 BLBplus -139.35, 152.22 61.66, 33.54 -71.04, 141.2 52.07, 82.92 82.4, -21.94 out-none out 15.389 Saltbr-none 999.0 HRD-in -71.47, -51.16 73.41, 1.02 none-out-out SNCnoo out-out ActLoopNT-out 7.459 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.45, -45.23 APE9-dihe-na -90.48, -7.37 APE8-dihe-out -66.85, -54.6 APE8-rot-na 183.3 APE67-dihe-in -71.76, -8.04 -52.06, -44.72 APE12-dist-out 18.487 APE11-dist-out 15.103 APE10-dist-out 19.519 APE9-dist-out 11.963 None None None XRAY 3.22 0.256 0.288 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juq TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JURB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.534 13.444 BLBplus -136.74, 172.29 64.43, 21.01 -64.29, 145.08 51.43, 88.21 72.32, -17.93 out-none out 13.058 Saltbr-none 999.0 HRD-in -74.46, -55.37 71.55, 3.38 none-out-out SNCnoo out-out ActLoopNT-out 7.607 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -61.97, 131.45 APE9-dihe-na 84.3, -3.37 APE8-dihe-out -70.0, -57.71 APE8-rot-na 184.79 APE67-dihe-in -71.0, 1.52 -53.02, -42.72 APE12-dist-out 18.483 APE11-dist-out 15.136 APE10-dist-out 19.742 APE9-dist-out 12.323 None None None XRAY 2.82 0.237 0.277 B 342 277 4 0 0 3 [[665, 930]] 1.0 7jur TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JUSB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.883 13.383 BLBplus -127.91, 171.08 62.77, 22.74 -63.47, 150.27 47.2, 86.11 68.89, -21.25 out-none out 13.513 Saltbr-none 999.0 HRD-in -73.66, -56.88 73.44, -2.22 none-out-out SNCnoo out-out ActLoopNT-out 7.508 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.38, 137.79 APE9-dihe-na 90.37, -24.33 APE8-dihe-out -66.74, -57.02 APE8-rot-na 187.61 APE67-dihe-in -75.11, -1.38 -58.95, -34.29 APE12-dist-out 18.421 APE11-dist-out 15.077 APE10-dist-out 19.629 APE9-dist-out 12.036 None None None XRAY 2.99 0.249 0.265 B 342 276 5 0 0 4 [[665, 930]] 1.0 7jus TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JUTB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.556 12.961 BLBplus -137.17, 153.82 70.92, 32.74 -74.86, 135.77 48.5, 88.18 74.13, -4.82 out-none out 14.209 Saltbr-none 999.0 HRD-in -85.35, -39.03 46.26, 13.05 none-out-out SNCnoo out-out ActLoopNT-out 7.196 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -53.57, -55.36 APE9-dihe-na -91.09, 3.18 APE8-dihe-out -71.8, -46.41 APE8-rot-na 181.21 APE67-dihe-in -68.18, -7.53 -62.86, -41.09 APE12-dist-out 18.127 APE11-dist-out 15.431 APE10-dist-out 19.558 APE9-dist-out 11.925 None None None XRAY 3.09 0.259 0.3 B 342 277 4 0 0 3 [[665, 930]] 1.0 7jut TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JUUB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.773 13.221 BLBplus -133.64, 151.36 70.73, 33.64 -75.25, 133.98 46.29, 83.15 80.08, -8.46 out-none out 14.433 Saltbr-none 999.0 HRD-in -73.56, -47.69 67.59, 2.06 none-out-out SNCnoo out-out ActLoopNT-out 7.385 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -58.47, -51.54 APE9-dihe-na -86.76, 0.87 APE8-dihe-out -74.62, -44.43 APE8-rot-na 183.38 APE67-dihe-in -73.96, -6.37 -64.52, -36.97 APE12-dist-out 18.347 APE11-dist-out 15.59 APE10-dist-out 19.794 APE9-dist-out 12.093 None None None XRAY 3.19 0.242 0.258 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juu TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7JUVB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.981 13.017 BLBplus -127.69, 170.94 63.29, 22.28 -64.16, 148.8 47.81, 86.58 68.48, -22.21 out-none out 13.605 Saltbr-none 999.0 HRD-in -73.05, -56.86 73.65, -2.34 none-out-out SNCnoo out-out ActLoopNT-out 7.503 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.84, 138.27 APE9-dihe-na 90.88, -24.23 APE8-dihe-out -67.14, -55.82 APE8-rot-na 188.73 APE67-dihe-in -75.46, -2.03 -58.92, -34.4 APE12-dist-out 18.296 APE11-dist-out 15.175 APE10-dist-out 19.835 APE9-dist-out 12.199 None None None XRAY 3.36 0.242 0.255 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juv TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
7UMBB 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.511 13.333 BLBplus -122.69, -178.17 55.62, 31.28 -75.96, 141.02 47.41, 88.89 74.01, -10.38 out-none out 13.077 Saltbr-none 999.0 HRD-in -83.2, -50.32 69.21, 5.46 none-out-out SNCnoo out-out ActLoopNT-out 7.53 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -52.68, 124.31 APE9-dihe-na 106.73, -20.32 APE8-dihe-out -71.55, -49.08 APE8-rot-na 185.38 APE67-dihe-in -79.33, 2.43 -65.58, -32.18 APE12-dist-out 18.119 APE11-dist-out 15.398 APE10-dist-out 19.723 APE9-dist-out 12.009 None None None XRAY 3.231 0.231 0.268 B 342 277 4 0 0 3 [[665, 930]] 1.0 7umb TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
5KKRB 650 932 950.0 6U7:1001 Type1.5_Back Pseudo DFGin 6.321 13.655 BLBplus -128.93, 179.91 52.58, 42.95 -101.79, 139.35 57.86, 93.35 75.81, -29.93 out-none out 15.513 Saltbr-none 999.0 HRD-in -70.05, -32.28 58.42, -72.83 none-out-out SNCnoo out-out ActLoopNT-out 9.734 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -86.49, -61.06 APE9-dihe-na -69.5, -38.89 APE8-dihe-out -67.94, -23.77 APE8-rot-na 175.88 APE67-dihe-in -97.86, 0.75 -65.39, -34.36 APE12-dist-out 17.673 APE11-dist-out 15.152 APE10-dist-out 19.8 APE9-dist-out 10.565 None None None XRAY 3.509 0.252 0.287 B 319 272 11 0 0 5 [[665, 930]] 1.0 5kkr TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2

TKL_KSR2 (Kinase suppressor of Ras 2)

Total number of chains: 9
Active chains: 0
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 9 100.0% 7JURB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KSR2_HUMAN 2Y4IB Q6VAB6 653 931 950.0 ATP:1932 ATPlike Pseudo DFGin 6.039 13.357 BLBplus -163.04, 167.92 56.95, 32.67 -75.07, 155.41 46.1, 92.34 53.05, 51.5 out-none out 15.58 Saltbr-none 999.0 HRD-in -80.25, -38.53 67.56, -67.09 none-out-out SNCnoo out-out ActLoopNT-out 10.43 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -56.45, -137.53 APE9-dihe-na -67.8, 7.84 APE8-dihe-out -54.46, -37.41 APE8-rot-na 170.99 APE67-dihe-in -92.05, 13.42 -60.84, -28.22 APE12-dist-out 17.417 APE11-dist-out 14.576 APE10-dist-out 17.158 APE9-dist-out 12.262 None None None XRAY 3.46 0.233 0.293 B 319 265 14 0 0 10 [[665, 930]] 1.0 2y4i Homo sapiens TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JUQB Q6VAB6 652 932 950.0 ADP:1001 ATPlike Pseudo DFGin 5.723 13.43 BLBplus -139.35, 152.22 61.66, 33.54 -71.04, 141.2 52.07, 82.92 82.4, -21.94 out-none out 15.389 Saltbr-none 999.0 HRD-in -71.47, -51.16 73.41, 1.02 none-out-out SNCnoo out-out ActLoopNT-out 7.459 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.45, -45.23 APE9-dihe-na -90.48, -7.37 APE8-dihe-out -66.85, -54.6 APE8-rot-na 183.3 APE67-dihe-in -71.76, -8.04 -52.06, -44.72 APE12-dist-out 18.487 APE11-dist-out 15.103 APE10-dist-out 19.519 APE9-dist-out 11.963 None None None XRAY 3.22 0.256 0.288 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juq Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JURB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.534 13.444 BLBplus -136.74, 172.29 64.43, 21.01 -64.29, 145.08 51.43, 88.21 72.32, -17.93 out-none out 13.058 Saltbr-none 999.0 HRD-in -74.46, -55.37 71.55, 3.38 none-out-out SNCnoo out-out ActLoopNT-out 7.607 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -61.97, 131.45 APE9-dihe-na 84.3, -3.37 APE8-dihe-out -70.0, -57.71 APE8-rot-na 184.79 APE67-dihe-in -71.0, 1.52 -53.02, -42.72 APE12-dist-out 18.483 APE11-dist-out 15.136 APE10-dist-out 19.742 APE9-dist-out 12.323 None None None XRAY 2.82 0.237 0.277 B 342 277 4 0 0 3 [[665, 930]] 1.0 7jur Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JUSB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.883 13.383 BLBplus -127.91, 171.08 62.77, 22.74 -63.47, 150.27 47.2, 86.11 68.89, -21.25 out-none out 13.513 Saltbr-none 999.0 HRD-in -73.66, -56.88 73.44, -2.22 none-out-out SNCnoo out-out ActLoopNT-out 7.508 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.38, 137.79 APE9-dihe-na 90.37, -24.33 APE8-dihe-out -66.74, -57.02 APE8-rot-na 187.61 APE67-dihe-in -75.11, -1.38 -58.95, -34.29 APE12-dist-out 18.421 APE11-dist-out 15.077 APE10-dist-out 19.629 APE9-dist-out 12.036 None None None XRAY 2.99 0.249 0.265 B 342 276 5 0 0 4 [[665, 930]] 1.0 7jus Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JUTB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.556 12.961 BLBplus -137.17, 153.82 70.92, 32.74 -74.86, 135.77 48.5, 88.18 74.13, -4.82 out-none out 14.209 Saltbr-none 999.0 HRD-in -85.35, -39.03 46.26, 13.05 none-out-out SNCnoo out-out ActLoopNT-out 7.196 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -53.57, -55.36 APE9-dihe-na -91.09, 3.18 APE8-dihe-out -71.8, -46.41 APE8-rot-na 181.21 APE67-dihe-in -68.18, -7.53 -62.86, -41.09 APE12-dist-out 18.127 APE11-dist-out 15.431 APE10-dist-out 19.558 APE9-dist-out 11.925 None None None XRAY 3.09 0.259 0.3 B 342 277 4 0 0 3 [[665, 930]] 1.0 7jut Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JUUB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.773 13.221 BLBplus -133.64, 151.36 70.73, 33.64 -75.25, 133.98 46.29, 83.15 80.08, -8.46 out-none out 14.433 Saltbr-none 999.0 HRD-in -73.56, -47.69 67.59, 2.06 none-out-out SNCnoo out-out ActLoopNT-out 7.385 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -58.47, -51.54 APE9-dihe-na -86.76, 0.87 APE8-dihe-out -74.62, -44.43 APE8-rot-na 183.38 APE67-dihe-in -73.96, -6.37 -64.52, -36.97 APE12-dist-out 18.347 APE11-dist-out 15.59 APE10-dist-out 19.794 APE9-dist-out 12.093 None None None XRAY 3.19 0.242 0.258 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juu Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7JUVB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.981 13.017 BLBplus -127.69, 170.94 63.29, 22.28 -64.16, 148.8 47.81, 86.58 68.48, -22.21 out-none out 13.605 Saltbr-none 999.0 HRD-in -73.05, -56.86 73.65, -2.34 none-out-out SNCnoo out-out ActLoopNT-out 7.503 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -57.84, 138.27 APE9-dihe-na 90.88, -24.23 APE8-dihe-out -67.14, -55.82 APE8-rot-na 188.73 APE67-dihe-in -75.46, -2.03 -58.92, -34.4 APE12-dist-out 18.296 APE11-dist-out 15.175 APE10-dist-out 19.835 APE9-dist-out 12.199 None None None XRAY 3.36 0.242 0.255 B 342 277 4 0 0 3 [[665, 930]] 1.0 7juv Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 7UMBB Q6VAB6 652 932 950.0 ANP:1001 ATPlike Pseudo DFGin 5.511 13.333 BLBplus -122.69, -178.17 55.62, 31.28 -75.96, 141.02 47.41, 88.89 74.01, -10.38 out-none out 13.077 Saltbr-none 999.0 HRD-in -83.2, -50.32 69.21, 5.46 none-out-out SNCnoo out-out ActLoopNT-out 7.53 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -52.68, 124.31 APE9-dihe-na 106.73, -20.32 APE8-dihe-out -71.55, -49.08 APE8-rot-na 185.38 APE67-dihe-in -79.33, 2.43 -65.58, -32.18 APE12-dist-out 18.119 APE11-dist-out 15.398 APE10-dist-out 19.723 APE9-dist-out 12.009 None None None XRAY 3.231 0.231 0.268 B 342 277 4 0 0 3 [[665, 930]] 1.0 7umb Homo sapiens TKL_KSR2_HUMAN TKL 1.5e-70 243.8 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
KSR2_HUMAN 5KKRB Q6VAB6 650 932 950.0 6U7:1001 Type1.5_Back Pseudo DFGin 6.321 13.655 BLBplus -128.93, 179.91 52.58, 42.95 -101.79, 139.35 57.86, 93.35 75.81, -29.93 out-none out 15.513 Saltbr-none 999.0 HRD-in -70.05, -32.28 58.42, -72.83 none-out-out SNCnoo out-out ActLoopNT-out 9.734 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -86.49, -61.06 APE9-dihe-na -69.5, -38.89 APE8-dihe-out -67.94, -23.77 APE8-rot-na 175.88 APE67-dihe-in -97.86, 0.75 -65.39, -34.36 APE12-dist-out 17.673 APE11-dist-out 15.152 APE10-dist-out 19.8 APE9-dist-out 10.565 None None None XRAY 3.509 0.252 0.287 B 319 272 11 0 0 5 [[665, 930]] 1.0 5kkr Homo sapiens TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2 267 266 802 803 804 806 808 692 710 714 783 785 784 786 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2

TKL_KSR2 (Kinase suppressor of Ras 2)

Total number of chains: 0
Active chains: 0
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name