TKL_IRAK1 (Interleukin-1 receptor-associated kinase 1)

Total number of chains: 4
Active chains: 4
Uniprot: IRAK1_HUMAN
Kinase Domain Residues: 207 - 521
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P51617-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P51617-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1
AF-P51617-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1
6BFNA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1
6BFNB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1

TKL_IRAK1 (Interleukin-1 receptor-associated kinase 1)

Total number of chains: 4
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P51617-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
IRAK1_HUMAN AF-P51617-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
IRAK1_HUMAN AF-P51617-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
IRAK1_HUMAN 6BFNA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
IRAK1_HUMAN 6BFNB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens

TKL_IRAK1 (Interleukin-1 receptor-associated kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism