| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P54753-K1A |
| DFGin | None | 4 | 5L6PA |
| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P54753-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 625 - 902 | None | None | 0 |
| 3ZFYA | 2.2 | Inactive | DFGin | None | in-out | none-in | No_ligand | No_ligand | 632 - 905 | None | None | 8 |
| 3ZFYB | 2.2 | Inactive | DFGin | None | in-none | none-in | No_ligand | No_ligand | 631 - 905 | None | None | 8 |
| 5L6OA | 1.88 | Inactive | DFGin | None | in-in | none-in | 6P6 | Type1 | 632 - 905 | A899P | None | 4 |
| 5L6PA | 2.26 | Inactive | DFGin | None | in-out | out-in | 6P8 | Type1 | 632 - 905 | A899P | None | 0 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P54753-K1A |
| DFGin | None | 4 | 5L6PA |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | EPHB3_HUMAN | AF-P54753-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 625 - 902 | None | None | 0 |
| Homo sapiens | EPHB3_HUMAN | 3ZFYA | 2.2 | Inactive | DFGin | None | in-out | none-in | No_ligand | No_ligand | 632 - 905 | None | None | 8 |
| Homo sapiens | EPHB3_HUMAN | 3ZFYB | 2.2 | Inactive | DFGin | None | in-none | none-in | No_ligand | No_ligand | 631 - 905 | None | None | 8 |
| Homo sapiens | EPHB3_HUMAN | 5L6OA | 1.88 | Inactive | DFGin | None | in-in | none-in | 6P6 | Type1 | 632 - 905 | A899P | None | 4 |
| Homo sapiens | EPHB3_HUMAN | 5L6PA | 2.26 | Inactive | DFGin | None | in-out | out-in | 6P8 | Type1 | 632 - 905 | A899P | None | 0 |