CK1_CSNK1E (Casein kinase I isoform epsilon)

Total number of chains: 16
Active chains: 6
Uniprot: KC1E_HUMAN
Kinase Domain Residues: 9 - 275
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 87.5% AF-P49674-K1A
DFGout BBAminus 2 12.5% 4HNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P49674-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 283 0 None None Casein kinase I isoform epsilon
AF-P49674-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 283 0 None None Casein kinase I isoform epsilon
4HOKC 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 294 0 None None Casein kinase I isoform epsilon
4HOKG 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKM 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 4 - 294 0 None None Casein kinase I isoform epsilon
4HOKW 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 294 0 None None Casein kinase I isoform epsilon
4HOKA 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKE 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKI 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKK 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKO 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKQ 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon
4HOKS 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 4 - 294 0 None None Casein kinase I isoform epsilon
4HOKU 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 293 0 None None Casein kinase I isoform epsilon
4HNIA 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 3 - 293 0 None None Casein kinase I isoform epsilon
4HNIB 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 1 - 293 0 None None Casein kinase I isoform epsilon

CK1_CSNK1E (Casein kinase I isoform epsilon)

Total number of chains: 16
Active chains: 6
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 87.5% AF-P49674-K1A
DFGout BBAminus 2 12.5% 4HNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KC1E_HUMAN AF-P49674-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 283 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN AF-P49674-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 283 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKC 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKG 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKM 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 4 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKW 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKA 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKE 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKI 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKK 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKO 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKQ 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKS 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 4 - 294 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HOKU 2.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 293 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HNIA 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 3 - 293 0 None None Casein kinase I isoform epsilon Homo sapiens
KC1E_HUMAN 4HNIB 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 1 - 293 0 None None Casein kinase I isoform epsilon Homo sapiens

CK1_CSNK1E (Casein kinase I isoform epsilon)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism