TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 6
Active chains: 4
Uniprot: UFO_HUMAN
Kinase Domain Residues: 536 - 805
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% AF-P30530-K1A
DFGin None 2 33.3% 5U6BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AXL AF-P30530-K1A P30530 528 813 894.0 No_ligand No_ligand Active DFGin 6.5058 13.5539 BLAminus -142.97, -177.46 54.99, 82.47 -95.2, 16.76 305.78, 109.79 -61.39, -29.33 in-in in 8.3922 Saltbr-in 2.7186 HRD-in -70.44, -46.92 67.06, -14.75 in-in-in SNCiii in-in ActLoopNT-in 2.9319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.04, 123.08 APE9-dihe-in -127.07, 152.19 APE8-dihe-in -78.28, 66.65 APE8-rot-na 37.06 APE67-dihe-in -70.1, -13.88 -39.12, -42.63 APE12-dist-na 13.8518 APE11-dist-na 8.3675 APE10-dist-na 10.4346 APE9-dist-in 6.7329 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[536, 805]] 1.0 AF-P30530-K1 TYR_AXL_HUMAN TYR 2.1e-92 315.0 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL AF-P30530-K3A P30530 528 813 894.0 No_ligand No_ligand Active DFGin 6.2324 13.8331 BLAminus -144.66, -174.09 52.88, 75.72 -88.8, 18.02 305.64, 110.36 -60.04, -33.35 in-in in 8.807 Saltbr-in 2.7316 HRD-in -80.34, -45.63 64.67, -8.78 in-in-in SNCiii in-in ActLoopNT-in 2.9336 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.19, 129.28 APE9-dihe-in -138.32, 152.93 APE8-dihe-in -77.01, 64.83 APE8-rot-na 36.94 APE67-dihe-in -74.37, -11.92 -53.18, -28.32 APE12-dist-na 14.0208 APE11-dist-na 8.5944 APE10-dist-na 10.28 APE9-dist-in 6.5517 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[536, 805]] 1.0 AF-P30530-K3 TYR_AXL_HUMAN TYR 2.1e-92 315.0 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL 5U6BB P30530 514 811 894.0 7YS:69001 Type1 Active DFGin 6.4909 14.2963 BLAminus -139.53, -173.29 61.22, 86.45 -106.0, 29.03 307.83, 103.64 -64.87, -30.42 in-in in 7.8513 Saltbr-in 2.813 HRD-in -66.12, -54.28 73.06, -10.58 in-in-in SNCiii in-in ActLoopNT-in 2.8593 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.99, 134.13 APE9-dihe-in -119.82, 152.84 APE8-dihe-in -77.43, 86.57 APE8-rot-na 26.16 APE67-dihe-in -70.55, -7.24 -43.37, -42.29 APE12-dist-na 14.0192 APE11-dist-na 8.617 APE10-dist-na 11.5579 APE9-dist-in 6.7625 None None None XRAY 2.84 0.212 0.239 B 307.0 289.0 9 30 27 3 [[536, 805]] 1.0 5u6b TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL 5U6BD P30530 514 811 894.0 7YS:69001 Type1 Active DFGin 6.4424 14.2292 BLAminus -139.85, -170.38 60.61, 83.62 -105.4, 26.58 306.88, 102.16 -67.77, -23.66 in-in in 7.7879 Saltbr-in 3.083 HRD-in -67.24, -54.45 72.53, -9.79 in-in-in SNCiii in-in ActLoopNT-in 2.8919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.89, 134.51 APE9-dihe-in -120.87, 152.67 APE8-dihe-in -77.97, 87.01 APE8-rot-na 26.02 APE67-dihe-in -70.8, -7.18 -43.66, -42.34 APE12-dist-na 13.8608 APE11-dist-na 8.414 APE10-dist-na 11.3047 APE9-dist-in 6.7025 None None None XRAY 2.84 0.212 0.239 D 307.0 289.0 9 30 27 3 [[536, 805]] 1.0 5u6b TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL 5U6BA P30530 521 813 894.0 7YS:69001 Type1 Inactive DFGin 6.3623 13.5788 None -138.45, -176.55 74.1, -59.44 62.23, 29.92 319.8, 103.87 51.42, 41.79 out-out out 13.7081 Saltbr-out 12.0892 HRD-in -66.09, -54.16 75.27, -12.42 out-out-none SNCoon out-none ActLoopNT-out 9.8826 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -58.78 APE8-rot-na 17.42 APE67-dihe-in -67.55, -5.96 -47.01, -39.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.84 0.212 0.239 A 307.0 270.0 23 30 14 16 [[536, 805]] 1.0 5u6b TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL 5U6BC P30530 521 813 894.0 7YS:69001 Type1 Inactive DFGin 6.4468 13.7913 None -138.61, -175.97 75.83, -59.43 64.34, 25.07 310.35, 105.78 53.72, 41.47 out-out out 13.6127 Saltbr-out 11.748 HRD-in -65.26, -53.97 74.88, -12.45 out-out-none SNCoon out-none ActLoopNT-out 9.6998 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -86.85 APE8-rot-na 343.56 APE67-dihe-in -67.51, -5.95 -41.15, -42.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.84 0.212 0.239 C 307.0 270.0 23 30 14 16 [[536, 805]] 1.0 5u6b TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO

TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 6
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% AF-P30530-K1A
DFGin None 2 33.3% 5U6BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AXL UFO_HUMAN AF-P30530-K1A P30530 528 813 894.0 No_ligand No_ligand Active DFGin 6.5058 13.5539 BLAminus -142.97, -177.46 54.99, 82.47 -95.2, 16.76 305.78, 109.79 -61.39, -29.33 in-in in 8.3922 Saltbr-in 2.7186 HRD-in -70.44, -46.92 67.06, -14.75 in-in-in SNCiii in-in ActLoopNT-in 2.9319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.04, 123.08 APE9-dihe-in -127.07, 152.19 APE8-dihe-in -78.28, 66.65 APE8-rot-na 37.06 APE67-dihe-in -70.1, -13.88 -39.12, -42.63 APE12-dist-na 13.8518 APE11-dist-na 8.3675 APE10-dist-na 10.4346 APE9-dist-in 6.7329 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[536, 805]] 1.0 AF-P30530-K1 Homo sapiens TYR_AXL_HUMAN TYR 2.1e-92 315.0 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL UFO_HUMAN AF-P30530-K3A P30530 528 813 894.0 No_ligand No_ligand Active DFGin 6.2324 13.8331 BLAminus -144.66, -174.09 52.88, 75.72 -88.8, 18.02 305.64, 110.36 -60.04, -33.35 in-in in 8.807 Saltbr-in 2.7316 HRD-in -80.34, -45.63 64.67, -8.78 in-in-in SNCiii in-in ActLoopNT-in 2.9336 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.19, 129.28 APE9-dihe-in -138.32, 152.93 APE8-dihe-in -77.01, 64.83 APE8-rot-na 36.94 APE67-dihe-in -74.37, -11.92 -53.18, -28.32 APE12-dist-na 14.0208 APE11-dist-na 8.5944 APE10-dist-na 10.28 APE9-dist-in 6.5517 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[536, 805]] 1.0 AF-P30530-K3 Homo sapiens TYR_AXL_HUMAN TYR 2.1e-92 315.0 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL UFO_HUMAN 5U6BB P30530 514 811 894.0 7YS:69001 Type1 Active DFGin 6.4909 14.2963 BLAminus -139.53, -173.29 61.22, 86.45 -106.0, 29.03 307.83, 103.64 -64.87, -30.42 in-in in 7.8513 Saltbr-in 2.813 HRD-in -66.12, -54.28 73.06, -10.58 in-in-in SNCiii in-in ActLoopNT-in 2.8593 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.99, 134.13 APE9-dihe-in -119.82, 152.84 APE8-dihe-in -77.43, 86.57 APE8-rot-na 26.16 APE67-dihe-in -70.55, -7.24 -43.37, -42.29 APE12-dist-na 14.0192 APE11-dist-na 8.617 APE10-dist-na 11.5579 APE9-dist-in 6.7625 None None None XRAY 2.84 0.212 0.239 B 307.0 289.0 9 30 27 3 [[536, 805]] 1.0 5u6b Homo sapiens TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL UFO_HUMAN 5U6BD P30530 514 811 894.0 7YS:69001 Type1 Active DFGin 6.4424 14.2292 BLAminus -139.85, -170.38 60.61, 83.62 -105.4, 26.58 306.88, 102.16 -67.77, -23.66 in-in in 7.7879 Saltbr-in 3.083 HRD-in -67.24, -54.45 72.53, -9.79 in-in-in SNCiii in-in ActLoopNT-in 2.8919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.89, 134.51 APE9-dihe-in -120.87, 152.67 APE8-dihe-in -77.97, 87.01 APE8-rot-na 26.02 APE67-dihe-in -70.8, -7.18 -43.66, -42.34 APE12-dist-na 13.8608 APE11-dist-na 8.414 APE10-dist-na 11.3047 APE9-dist-in 6.7025 None None None XRAY 2.84 0.212 0.239 D 307.0 289.0 9 30 27 3 [[536, 805]] 1.0 5u6b Homo sapiens TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL UFO_HUMAN 5U6BA P30530 521 813 894.0 7YS:69001 Type1 Inactive DFGin 6.3623 13.5788 None -138.45, -176.55 74.1, -59.44 62.23, 29.92 319.8, 103.87 51.42, 41.79 out-out out 13.7081 Saltbr-out 12.0892 HRD-in -66.09, -54.16 75.27, -12.42 out-out-none SNCoon out-none ActLoopNT-out 9.8826 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -58.78 APE8-rot-na 17.42 APE67-dihe-in -67.55, -5.96 -47.01, -39.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.84 0.212 0.239 A 307.0 270.0 23 30 14 16 [[536, 805]] 1.0 5u6b Homo sapiens TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO
AXL UFO_HUMAN 5U6BC P30530 521 813 894.0 7YS:69001 Type1 Inactive DFGin 6.4468 13.7913 None -138.61, -175.97 75.83, -59.43 64.34, 25.07 310.35, 105.78 53.72, 41.47 out-out out 13.6127 Saltbr-out 11.748 HRD-in -65.26, -53.97 74.88, -12.45 out-out-none SNCoon out-none ActLoopNT-out 9.6998 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -86.85 APE8-rot-na 343.56 APE67-dihe-in -67.51, -5.95 -41.15, -42.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.84 0.212 0.239 C 307.0 270.0 23 30 14 16 [[536, 805]] 1.0 5u6b Homo sapiens TYR_AXL_HUMAN TYR 2.8e-92 314.7 2.0 260.0 259.0 689 690 691 693 695 567 585 589 669 671 670 672.0 731 719 714 713 712 711 710 709 708 621 Tyrosine-protein kinase receptor UFO

TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name