CAMK_AURKBA (Aurora kinase B-A)

Total number of chains: 0
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

CAMK_AURKBA (Aurora kinase B-A)

Total number of chains: 23
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 22 95.7% 4C2VA
DFGin None 1 4.3% 4B8LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AUKBA_XENLA 4C2WA Q6DE08 88 356 361.0 ANP:1001 ATPlike Inactive DFGin 5.524 15.79 ABAminus -114.94, -31.28 -113.37, 121.43 -114.18, 23.33 282.52, 84.1 -51.89, -43.92 out-out out 11.268 Saltbr-out 4.973 HRD-in -79.83, -53.41 73.71, 4.05 out-in-in SNCoii in-in ActLoopNT-in 2.893 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.21, 165.55 APE9-dihe-na 112.48, -144.66 APE8-dihe-in -138.33, 133.06 APE8-rot-in 294.04 APE67-dihe-in -66.35, -18.01 -34.41, -59.11 APE12-dist-in 8.359 APE11-dist-in 10.941 APE10-dist-in 5.531 APE9-dist-in 3.561 None TPO248 TPO248 XRAY 1.7 0.158 0.195 A 279 269 0 0 0 0 [[93, 343]] 1.0 4c2w Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.3e-77 265.7 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2WB Q6DE08 78 355 361.0 ANP:1002 ATPlike Inactive DFGin 5.81 15.787 ABAminus -118.01, -19.02 -130.42, 119.39 -114.99, 28.58 284.95, 75.85 -64.5, -21.38 out-out out 10.763 Saltbr-out 4.74 HRD-in -76.03, -52.74 71.93, -3.36 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.86, 167.53 APE9-dihe-na 123.0, -151.95 APE8-dihe-in -138.83, 132.09 APE8-rot-in 301.48 APE67-dihe-in -63.95, -21.5 -45.73, -54.15 APE12-dist-in 8.042 APE11-dist-in 10.769 APE10-dist-in 5.323 APE9-dist-in 3.606 None TPO248 TPO248 XRAY 1.7 0.158 0.195 B 279 278 0 0 0 0 [[93, 343]] 1.0 4c2w Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.3e-77 265.7 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFXA Q6DE08 86 356 361.0 No_ligand No_ligand Inactive DFGin 5.417 15.644 ABAminus -107.61, -30.67 -113.86, 136.24 -125.93, 31.94 284.55, 79.69 -57.08, -32.81 out-out out 10.742 Saltbr-out 5.903 HRD-in -78.02, -52.87 68.01, 8.08 out-in-in SNCoii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.53, 166.48 APE9-dihe-na 119.17, -143.63 APE8-dihe-in -135.39, 135.9 APE8-rot-in 296.62 APE67-dihe-in -64.58, -15.06 -33.93, -64.18 APE12-dist-in 8.332 APE11-dist-in 10.975 APE10-dist-in 5.447 APE9-dist-in 3.513 None TPO248 TPO248 XRAY 1.8 0.197 0.226 A 284 271 0 0 0 0 [[93, 343]] 1.0 2bfx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFXB Q6DE08 78 357 361.0 No_ligand No_ligand Inactive DFGin 5.899 15.801 ABAminus -114.94, -15.81 -125.51, 121.42 -115.63, 30.4 283.27, 76.11 -58.42, -23.3 out-out out 10.771 Saltbr-out 5.829 HRD-in -78.55, -49.03 70.9, -1.43 out-in-in SNCoii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.32, 166.14 APE9-dihe-na 126.8, -152.31 APE8-dihe-in -135.28, 133.05 APE8-rot-in 301.34 APE67-dihe-in -62.87, -20.68 -38.7, -58.88 APE12-dist-in 7.973 APE11-dist-in 10.802 APE10-dist-in 5.289 APE9-dist-in 3.544 None TPO248 TPO248 XRAY 1.8 0.197 0.226 B 284 277 3 0 0 0 [[93, 343]] 1.0 2bfx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5EYKB Q6DE08 81 356 361.0 5U5:401 Type1 Inactive DFGin 6.068 16.575 ABAminus -112.09, -11.83 -128.8, 128.82 -123.57, 29.05 279.71, 82.37 -53.88, -31.06 out-out out 11.193 Saltbr-out 6.626 HRD-in -71.23, -53.97 71.23, 1.84 out-in-in SNCoii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.26, 167.32 APE9-dihe-na 120.55, -149.48 APE8-dihe-in -136.43, 131.31 APE8-rot-in 300.33 APE67-dihe-in -64.5, -20.98 -31.7, -60.74 APE12-dist-in 7.777 APE11-dist-in 10.806 APE10-dist-in 5.18 APE9-dist-in 3.586 G96V TPO248 TPO248 XRAY 1.93 0.2 0.222 B 276 276 0 0 0 0 [[93, 343]] 1.0 5eyk Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.3e-77 264.5 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5K3YA Q6DE08 88 355 361.0 6Q4:401 Type1 Inactive DFGin 5.39 15.764 ABAminus -129.89, 15.53 -140.6, 135.46 -127.58, 29.55 283.48, 83.56 -53.93, -37.13 out-out out 10.789 Saltbr-out 5.917 HRD-in -76.28, -53.29 71.53, 4.3 out-in-in SNCoii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.34, 166.48 APE9-dihe-na 110.58, -147.89 APE8-dihe-in -123.3, 136.87 APE8-rot-in 311.45 APE67-dihe-in -64.31, -18.32 -33.25, -62.05 APE12-dist-in 8.083 APE11-dist-in 11.027 APE10-dist-in 5.386 APE9-dist-in 3.654 None TPO248 TPO248 XRAY 1.6 0.181 0.201 A 280 268 0 0 0 0 [[93, 343]] 1.0 5k3y Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.6e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5K3YB Q6DE08 79 356 361.0 6Q4:401 Type1 Inactive DFGin 5.642 16.138 ABAminus -117.0, -3.6 -132.91, 128.3 -120.32, 27.56 282.79, 83.07 -51.2, -35.51 out-out out 10.949 Saltbr-out 6.516 HRD-in -73.97, -54.22 72.01, 3.24 out-in-in SNCoii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.41, 165.86 APE9-dihe-na 121.1, -153.98 APE8-dihe-in -133.93, 133.55 APE8-rot-in 306.92 APE67-dihe-in -62.61, -22.3 -33.68, -61.96 APE12-dist-in 7.693 APE11-dist-in 10.741 APE10-dist-in 5.142 APE9-dist-in 3.565 None TPO248 TPO248 XRAY 1.6 0.181 0.201 B 280 278 0 0 0 0 [[93, 343]] 1.0 5k3y Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.6e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFYA Q6DE08 86 357 361.0 H1N:1357 Type1 Inactive DFGin 5.534 15.709 ABAminus -116.84, -1.88 -135.6, 140.82 -132.52, 30.57 278.95, 83.35 -56.9, -28.81 out-out out 10.576 Saltbr-out 3.965 HRD-in -79.01, -51.98 70.46, 4.19 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.04, 167.81 APE9-dihe-na 113.75, -150.39 APE8-dihe-in -125.82, 135.68 APE8-rot-in 312.13 APE67-dihe-in -68.48, -12.78 -29.46, -62.69 APE12-dist-in 8.215 APE11-dist-in 10.912 APE10-dist-in 5.385 APE9-dist-in 3.677 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 A 284 272 0 0 0 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFYB Q6DE08 78 357 361.0 H1N:1357 Type1 Inactive DFGin 5.527 15.879 ABAminus -115.69, -5.46 -135.16, 135.85 -127.64, 30.68 282.8, 80.72 -58.12, -29.16 out-out out 10.935 Saltbr-out 5.575 HRD-in -77.36, -51.18 70.55, 1.06 out-in-in SNCoii in-in ActLoopNT-in 2.902 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.63, 164.67 APE9-dihe-na 131.32, -159.09 APE8-dihe-in -135.77, 136.74 APE8-rot-in 298.0 APE67-dihe-in -65.1, -17.6 -34.73, -62.41 APE12-dist-in 7.84 APE11-dist-in 10.617 APE10-dist-in 5.177 APE9-dist-in 3.585 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 B 284 280 0 0 0 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGOA Q6DE08 87 355 361.0 AD5:1357 Type1 Inactive DFGin 5.479 15.718 ABAminus -110.64, -24.62 -124.76, 141.65 -131.15, 31.33 282.63, 81.87 -58.37, -34.49 out-out out 10.606 Saltbr-out 5.911 HRD-in -78.19, -53.38 72.25, 5.89 out-in-in SNCoii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.76, 168.21 APE9-dihe-na 111.78, -137.46 APE8-dihe-in -139.08, 132.11 APE8-rot-in 300.75 APE67-dihe-in -68.65, -14.37 -34.13, -60.06 APE12-dist-in 8.213 APE11-dist-in 10.918 APE10-dist-in 5.335 APE9-dist-in 3.48 None TPO248 TPO248 XRAY 1.7 0.199 0.229 A 284 269 0 0 0 0 [[93, 343]] 1.0 2vgo Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGOB Q6DE08 78 357 361.0 AD5:1359 Type1 Inactive DFGin 5.716 15.87 ABAminus -116.0, -24.11 -123.94, 124.0 -116.54, 29.26 283.63, 82.09 -65.8, -19.18 out-out out 10.9 Saltbr-out 4.048 HRD-in -76.91, -53.59 76.76, 0.28 out-in-in SNCoii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.18, 164.95 APE9-dihe-na 125.46, -147.72 APE8-dihe-in -139.32, 137.17 APE8-rot-in 306.13 APE67-dihe-in -63.38, -20.56 -43.93, -56.51 APE12-dist-in 7.861 APE11-dist-in 10.791 APE10-dist-in 5.234 APE9-dist-in 3.475 None TPO248 TPO248 XRAY 1.7 0.199 0.229 B 284 278 2 0 0 0 [[93, 343]] 1.0 2vgo Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGPA Q6DE08 88 356 361.0 AD6:1357 Type1 Inactive DFGin 5.449 15.891 ABAminus -98.3, -33.69 -126.95, 134.94 -124.01, 35.67 285.65, 84.26 -61.41, -32.04 out-out out 10.762 Saltbr-out 5.952 HRD-in -76.86, -54.63 73.7, 5.15 out-in-in SNCoii in-in ActLoopNT-in 2.97 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.89, 166.18 APE9-dihe-na 114.03, -139.03 APE8-dihe-in -137.76, 134.4 APE8-rot-in 302.62 APE67-dihe-in -68.68, -14.97 -37.15, -59.6 APE12-dist-in 8.28 APE11-dist-in 10.956 APE10-dist-in 5.356 APE9-dist-in 3.514 None TPO248 TPO248 XRAY 1.7 0.208 0.243 A 284 266 3 0 0 0 [[93, 343]] 1.0 2vgp Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGPB Q6DE08 78 355 361.0 AD6:1356 Type1 Inactive DFGin 5.859 15.987 ABAminus -105.69, -38.32 -114.16, 121.11 -114.2, 30.35 282.27, 78.52 -64.28, -21.51 out-out out 10.998 Saltbr-out 5.808 HRD-in -76.18, -52.02 74.91, -0.98 out-in-in SNCoii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.19, 163.44 APE9-dihe-na 125.86, -148.39 APE8-dihe-in -139.78, 135.67 APE8-rot-in 306.38 APE67-dihe-in -62.24, -22.22 -42.75, -57.14 APE12-dist-in 7.943 APE11-dist-in 10.793 APE10-dist-in 5.269 APE9-dist-in 3.582 None TPO248 TPO248 XRAY 1.7 0.208 0.243 B 284 278 0 0 0 0 [[93, 343]] 1.0 2vgp Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 3ZTXA Q6DE08 87 356 361.0 ZTX:1357 Type1 Inactive DFGin 5.292 15.355 ABAminus -114.92, -21.17 -133.22, 134.06 -123.23, 32.99 282.31, 84.28 -61.19, -34.71 out-out out 10.451 Saltbr-out 6.493 HRD-in -82.01, -52.17 75.29, 3.59 out-in-in SNCoii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.09, 163.72 APE9-dihe-na 117.29, -143.4 APE8-dihe-in -134.95, 133.3 APE8-rot-in 299.51 APE67-dihe-in -67.73, -15.78 -33.4, -58.65 APE12-dist-in 8.148 APE11-dist-in 10.87 APE10-dist-in 5.199 APE9-dist-in 3.624 None TPO248 TPO248 XRAY 1.95 0.188 0.226 A 284 270 0 0 0 0 [[93, 343]] 1.0 3ztx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 3ZTXB Q6DE08 78 355 361.0 ZTX:1356 Type1 Inactive DFGin 5.668 15.568 ABAminus -113.33, -30.48 -126.05, 115.12 -108.97, 32.49 284.32, 77.45 -65.15, -25.59 out-out out 10.53 Saltbr-out 5.115 HRD-in -80.99, -52.67 76.25, 3.65 out-in-in SNCoii in-in ActLoopNT-in 3.018 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.8, 162.24 APE9-dihe-na 128.32, -146.73 APE8-dihe-in -138.05, 133.93 APE8-rot-in 300.77 APE67-dihe-in -61.78, -24.54 -38.44, -59.14 APE12-dist-in 7.738 APE11-dist-in 10.696 APE10-dist-in 5.187 APE9-dist-in 3.568 None TPO248 TPO248 XRAY 1.95 0.188 0.226 B 284 273 5 0 0 0 [[93, 343]] 1.0 3ztx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8MA Q6DE08 87 357 361.0 VX6:1359 Type1 Inactive DFGin 5.474 15.774 ABAminus -107.28, -33.64 -117.85, 130.37 -121.34, 30.36 281.58, 83.31 -63.32, -28.71 out-out out 10.587 Saltbr-out 6.05 HRD-in -78.01, -57.17 76.89, 5.94 out-in-in SNCoii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.01, 165.76 APE9-dihe-na 112.26, -138.97 APE8-dihe-in -136.32, 135.05 APE8-rot-in 307.84 APE67-dihe-in -64.19, -18.21 -36.05, -60.56 APE12-dist-in 8.192 APE11-dist-in 10.95 APE10-dist-in 5.343 APE9-dist-in 3.517 None TPO248 TPO248 XRAY 1.85 0.193 0.236 A 286 271 0 0 0 0 [[93, 343]] 1.0 4b8m Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8MB Q6DE08 78 357 361.0 VX6:1359 Type1 Inactive DFGin 5.753 15.874 ABAminus -107.1, -42.62 -111.3, 118.7 -113.47, 25.97 282.13, 80.51 -60.76, -22.0 out-out out 10.633 Saltbr-out 5.409 HRD-in -78.11, -51.63 73.89, 2.84 out-in-in SNCoii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.93, 168.47 APE9-dihe-na 121.34, -152.05 APE8-dihe-in -136.52, 138.0 APE8-rot-in 305.16 APE67-dihe-in -64.39, -18.52 -45.42, -55.73 APE12-dist-in 7.957 APE11-dist-in 10.853 APE10-dist-in 5.267 APE9-dist-in 3.484 None TPO248 TPO248 XRAY 1.85 0.193 0.236 B 286 280 0 0 0 0 [[93, 343]] 1.0 4b8m Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5EYKA Q6DE08 88 355 361.0 5U5:401 Type1.5_Back Inactive DFGin 5.818 16.494 ABAminus -113.53, -11.3 -127.89, 127.9 -123.36, 28.44 280.86, 83.1 -54.75, -34.31 out-out out 11.167 Saltbr-out 6.298 HRD-in -71.81, -53.56 69.94, 2.34 out-in-in SNCoii in-in ActLoopNT-in 2.9 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.24, 164.73 APE9-dihe-na 118.09, -143.76 APE8-dihe-in -130.69, 133.69 APE8-rot-in 302.79 APE67-dihe-in -64.89, -21.02 -31.66, -60.88 APE12-dist-in 8.059 APE11-dist-in 11.155 APE10-dist-in 5.517 APE9-dist-in 3.686 G96V TPO248 TPO248 XRAY 1.93 0.2 0.222 A 276 264 4 0 0 4 [[93, 343]] 1.0 5eyk Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.3e-77 264.5 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VRXB Q6DE08 77 355 361.0 447:1356 Type1.5_Back Inactive DFGin 5.653 15.758 ABAminus -113.46, -27.26 -123.92, 110.09 -106.03, 30.29 284.23, 82.27 -65.09, -18.68 out-out out 10.721 Saltbr-out 5.511 HRD-in -80.07, -54.58 78.53, 0.16 out-in-in SNCoii in-in ActLoopNT-in 2.968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.63, 165.93 APE9-dihe-na 123.43, -149.16 APE8-dihe-in -135.57, 133.36 APE8-rot-in 303.41 APE67-dihe-in -62.94, -19.54 -41.29, -57.33 APE12-dist-in 7.88 APE11-dist-in 10.747 APE10-dist-in 5.203 APE9-dist-in 3.498 None TPO248 TPO248 XRAY 1.86 0.191 0.243 B 285 275 4 0 0 0 [[93, 343]] 1.0 2vrx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VRXA Q6DE08 87 355 361.0 447:1356 Type1.5_Front Inactive DFGin 5.42 15.778 ABAminus -105.62, -30.67 -123.67, 131.33 -117.99, 34.15 285.03, 83.66 -62.28, -30.72 out-out out 10.682 Saltbr-out 8.585 HRD-in -81.76, -55.95 77.01, 3.35 out-in-in SNCoii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.89, 162.13 APE9-dihe-na 112.16, -139.2 APE8-dihe-in -134.38, 133.56 APE8-rot-in 313.33 APE67-dihe-in -66.93, -14.33 -36.35, -56.78 APE12-dist-in 8.24 APE11-dist-in 10.984 APE10-dist-in 5.366 APE9-dist-in 3.599 None TPO248 TPO248 XRAY 1.86 0.191 0.243 A 285 269 0 0 0 0 [[93, 343]] 1.0 2vrx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2VA Q6DE08 87 357 361.0 YJA:1357 Type1.5_Front Inactive DFGin 5.69 15.549 ABAminus -108.16, -35.27 -114.73, 124.49 -117.48, 35.02 287.24, 73.89 -61.26, -33.55 out-out out 10.498 Saltbr-out 6.613 HRD-in -78.14, -58.65 78.38, 3.8 out-in-in SNCoii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.3, 162.85 APE9-dihe-na 114.08, -146.04 APE8-dihe-in -135.51, 133.89 APE8-rot-in 294.11 APE67-dihe-in -71.33, -17.09 -36.81, -55.94 APE12-dist-in 8.288 APE11-dist-in 10.871 APE10-dist-in 5.538 APE9-dist-in 3.614 None TPO248 TPO248 XRAY 1.49 0.168 0.197 A 285 271 0 0 0 0 [[93, 343]] 1.0 4c2v Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2VB Q6DE08 76 356 361.0 YJA:1357 Type1.5_Front Inactive DFGin 5.942 15.883 ABAminus -109.55, -42.74 -106.71, 117.87 -113.37, 30.44 284.56, 79.44 -66.62, -22.24 out-out out 10.936 Saltbr-out 5.894 HRD-in -82.35, -52.94 75.14, -4.14 out-in-in SNCoii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.26, 161.88 APE9-dihe-na 127.85, -152.7 APE8-dihe-in -130.87, 132.44 APE8-rot-in 296.15 APE67-dihe-in -67.07, -19.19 -44.45, -53.34 APE12-dist-in 8.111 APE11-dist-in 10.915 APE10-dist-in 5.332 APE9-dist-in 3.644 None TPO248 TPO248 XRAY 1.49 0.168 0.197 B 285 281 0 0 0 0 [[93, 343]] 1.0 4c2v Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8LA Q6DE08 87 351 361.0 A0P:1352 Type1 Inactive DFGin 7.552 15.564 None -81.6, -93.69 -89.24, 141.54 -107.67, 999.0 288.18, 65.55 999.0, 999.0 out-out out 10.561 Saltbr-out 5.944 HRD-in -91.78, -45.75 80.25, -35.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 143.01 APE8-rot-in 294.25 APE67-dihe-in -54.23, -29.34 -30.25, -64.92 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 P353G None None XRAY 3.0 0.24 0.297 A 286 249 16 0 0 16 [[93, 343]] 1.0 4b8l Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A

CAMK_AURKBA (Aurora kinase B-A)

Total number of chains: 23
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 22 95.7% 4C2VA
DFGin None 1 4.3% 4B8LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AUKBA_XENLA 4C2WA Q6DE08 88 356 361.0 ANP:1001 ATPlike Inactive DFGin 5.524 15.79 ABAminus -114.94, -31.28 -113.37, 121.43 -114.18, 23.33 282.52, 84.1 -51.89, -43.92 out-out out 11.268 Saltbr-out 4.973 HRD-in -79.83, -53.41 73.71, 4.05 out-in-in SNCoii in-in ActLoopNT-in 2.893 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.21, 165.55 APE9-dihe-na 112.48, -144.66 APE8-dihe-in -138.33, 133.06 APE8-rot-in 294.04 APE67-dihe-in -66.35, -18.01 -34.41, -59.11 APE12-dist-in 8.359 APE11-dist-in 10.941 APE10-dist-in 5.531 APE9-dist-in 3.561 None TPO248 TPO248 XRAY 1.7 0.158 0.195 A 279 269 0 0 0 0 [[93, 343]] 1.0 4c2w Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.3e-77 265.7 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2WB Q6DE08 78 355 361.0 ANP:1002 ATPlike Inactive DFGin 5.81 15.787 ABAminus -118.01, -19.02 -130.42, 119.39 -114.99, 28.58 284.95, 75.85 -64.5, -21.38 out-out out 10.763 Saltbr-out 4.74 HRD-in -76.03, -52.74 71.93, -3.36 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.86, 167.53 APE9-dihe-na 123.0, -151.95 APE8-dihe-in -138.83, 132.09 APE8-rot-in 301.48 APE67-dihe-in -63.95, -21.5 -45.73, -54.15 APE12-dist-in 8.042 APE11-dist-in 10.769 APE10-dist-in 5.323 APE9-dist-in 3.606 None TPO248 TPO248 XRAY 1.7 0.158 0.195 B 279 278 0 0 0 0 [[93, 343]] 1.0 4c2w Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.3e-77 265.7 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFXA Q6DE08 86 356 361.0 No_ligand No_ligand Inactive DFGin 5.417 15.644 ABAminus -107.61, -30.67 -113.86, 136.24 -125.93, 31.94 284.55, 79.69 -57.08, -32.81 out-out out 10.742 Saltbr-out 5.903 HRD-in -78.02, -52.87 68.01, 8.08 out-in-in SNCoii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.53, 166.48 APE9-dihe-na 119.17, -143.63 APE8-dihe-in -135.39, 135.9 APE8-rot-in 296.62 APE67-dihe-in -64.58, -15.06 -33.93, -64.18 APE12-dist-in 8.332 APE11-dist-in 10.975 APE10-dist-in 5.447 APE9-dist-in 3.513 None TPO248 TPO248 XRAY 1.8 0.197 0.226 A 284 271 0 0 0 0 [[93, 343]] 1.0 2bfx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFXB Q6DE08 78 357 361.0 No_ligand No_ligand Inactive DFGin 5.899 15.801 ABAminus -114.94, -15.81 -125.51, 121.42 -115.63, 30.4 283.27, 76.11 -58.42, -23.3 out-out out 10.771 Saltbr-out 5.829 HRD-in -78.55, -49.03 70.9, -1.43 out-in-in SNCoii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.32, 166.14 APE9-dihe-na 126.8, -152.31 APE8-dihe-in -135.28, 133.05 APE8-rot-in 301.34 APE67-dihe-in -62.87, -20.68 -38.7, -58.88 APE12-dist-in 7.973 APE11-dist-in 10.802 APE10-dist-in 5.289 APE9-dist-in 3.544 None TPO248 TPO248 XRAY 1.8 0.197 0.226 B 284 277 3 0 0 0 [[93, 343]] 1.0 2bfx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5EYKB Q6DE08 81 356 361.0 5U5:401 Type1 Inactive DFGin 6.068 16.575 ABAminus -112.09, -11.83 -128.8, 128.82 -123.57, 29.05 279.71, 82.37 -53.88, -31.06 out-out out 11.193 Saltbr-out 6.626 HRD-in -71.23, -53.97 71.23, 1.84 out-in-in SNCoii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.26, 167.32 APE9-dihe-na 120.55, -149.48 APE8-dihe-in -136.43, 131.31 APE8-rot-in 300.33 APE67-dihe-in -64.5, -20.98 -31.7, -60.74 APE12-dist-in 7.777 APE11-dist-in 10.806 APE10-dist-in 5.18 APE9-dist-in 3.586 G96V TPO248 TPO248 XRAY 1.93 0.2 0.222 B 276 276 0 0 0 0 [[93, 343]] 1.0 5eyk Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.3e-77 264.5 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5K3YA Q6DE08 88 355 361.0 6Q4:401 Type1 Inactive DFGin 5.39 15.764 ABAminus -129.89, 15.53 -140.6, 135.46 -127.58, 29.55 283.48, 83.56 -53.93, -37.13 out-out out 10.789 Saltbr-out 5.917 HRD-in -76.28, -53.29 71.53, 4.3 out-in-in SNCoii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.34, 166.48 APE9-dihe-na 110.58, -147.89 APE8-dihe-in -123.3, 136.87 APE8-rot-in 311.45 APE67-dihe-in -64.31, -18.32 -33.25, -62.05 APE12-dist-in 8.083 APE11-dist-in 11.027 APE10-dist-in 5.386 APE9-dist-in 3.654 None TPO248 TPO248 XRAY 1.6 0.181 0.201 A 280 268 0 0 0 0 [[93, 343]] 1.0 5k3y Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.6e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5K3YB Q6DE08 79 356 361.0 6Q4:401 Type1 Inactive DFGin 5.642 16.138 ABAminus -117.0, -3.6 -132.91, 128.3 -120.32, 27.56 282.79, 83.07 -51.2, -35.51 out-out out 10.949 Saltbr-out 6.516 HRD-in -73.97, -54.22 72.01, 3.24 out-in-in SNCoii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.41, 165.86 APE9-dihe-na 121.1, -153.98 APE8-dihe-in -133.93, 133.55 APE8-rot-in 306.92 APE67-dihe-in -62.61, -22.3 -33.68, -61.96 APE12-dist-in 7.693 APE11-dist-in 10.741 APE10-dist-in 5.142 APE9-dist-in 3.565 None TPO248 TPO248 XRAY 1.6 0.181 0.201 B 280 278 0 0 0 0 [[93, 343]] 1.0 5k3y Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.6e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFYA Q6DE08 86 357 361.0 H1N:1357 Type1 Inactive DFGin 5.534 15.709 ABAminus -116.84, -1.88 -135.6, 140.82 -132.52, 30.57 278.95, 83.35 -56.9, -28.81 out-out out 10.576 Saltbr-out 3.965 HRD-in -79.01, -51.98 70.46, 4.19 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.04, 167.81 APE9-dihe-na 113.75, -150.39 APE8-dihe-in -125.82, 135.68 APE8-rot-in 312.13 APE67-dihe-in -68.48, -12.78 -29.46, -62.69 APE12-dist-in 8.215 APE11-dist-in 10.912 APE10-dist-in 5.385 APE9-dist-in 3.677 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 A 284 272 0 0 0 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2BFYB Q6DE08 78 357 361.0 H1N:1357 Type1 Inactive DFGin 5.527 15.879 ABAminus -115.69, -5.46 -135.16, 135.85 -127.64, 30.68 282.8, 80.72 -58.12, -29.16 out-out out 10.935 Saltbr-out 5.575 HRD-in -77.36, -51.18 70.55, 1.06 out-in-in SNCoii in-in ActLoopNT-in 2.902 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.63, 164.67 APE9-dihe-na 131.32, -159.09 APE8-dihe-in -135.77, 136.74 APE8-rot-in 298.0 APE67-dihe-in -65.1, -17.6 -34.73, -62.41 APE12-dist-in 7.84 APE11-dist-in 10.617 APE10-dist-in 5.177 APE9-dist-in 3.585 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 B 284 280 0 0 0 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGOA Q6DE08 87 355 361.0 AD5:1357 Type1 Inactive DFGin 5.479 15.718 ABAminus -110.64, -24.62 -124.76, 141.65 -131.15, 31.33 282.63, 81.87 -58.37, -34.49 out-out out 10.606 Saltbr-out 5.911 HRD-in -78.19, -53.38 72.25, 5.89 out-in-in SNCoii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.76, 168.21 APE9-dihe-na 111.78, -137.46 APE8-dihe-in -139.08, 132.11 APE8-rot-in 300.75 APE67-dihe-in -68.65, -14.37 -34.13, -60.06 APE12-dist-in 8.213 APE11-dist-in 10.918 APE10-dist-in 5.335 APE9-dist-in 3.48 None TPO248 TPO248 XRAY 1.7 0.199 0.229 A 284 269 0 0 0 0 [[93, 343]] 1.0 2vgo Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGOB Q6DE08 78 357 361.0 AD5:1359 Type1 Inactive DFGin 5.716 15.87 ABAminus -116.0, -24.11 -123.94, 124.0 -116.54, 29.26 283.63, 82.09 -65.8, -19.18 out-out out 10.9 Saltbr-out 4.048 HRD-in -76.91, -53.59 76.76, 0.28 out-in-in SNCoii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.18, 164.95 APE9-dihe-na 125.46, -147.72 APE8-dihe-in -139.32, 137.17 APE8-rot-in 306.13 APE67-dihe-in -63.38, -20.56 -43.93, -56.51 APE12-dist-in 7.861 APE11-dist-in 10.791 APE10-dist-in 5.234 APE9-dist-in 3.475 None TPO248 TPO248 XRAY 1.7 0.199 0.229 B 284 278 2 0 0 0 [[93, 343]] 1.0 2vgo Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGPA Q6DE08 88 356 361.0 AD6:1357 Type1 Inactive DFGin 5.449 15.891 ABAminus -98.3, -33.69 -126.95, 134.94 -124.01, 35.67 285.65, 84.26 -61.41, -32.04 out-out out 10.762 Saltbr-out 5.952 HRD-in -76.86, -54.63 73.7, 5.15 out-in-in SNCoii in-in ActLoopNT-in 2.97 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.89, 166.18 APE9-dihe-na 114.03, -139.03 APE8-dihe-in -137.76, 134.4 APE8-rot-in 302.62 APE67-dihe-in -68.68, -14.97 -37.15, -59.6 APE12-dist-in 8.28 APE11-dist-in 10.956 APE10-dist-in 5.356 APE9-dist-in 3.514 None TPO248 TPO248 XRAY 1.7 0.208 0.243 A 284 266 3 0 0 0 [[93, 343]] 1.0 2vgp Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VGPB Q6DE08 78 355 361.0 AD6:1356 Type1 Inactive DFGin 5.859 15.987 ABAminus -105.69, -38.32 -114.16, 121.11 -114.2, 30.35 282.27, 78.52 -64.28, -21.51 out-out out 10.998 Saltbr-out 5.808 HRD-in -76.18, -52.02 74.91, -0.98 out-in-in SNCoii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.19, 163.44 APE9-dihe-na 125.86, -148.39 APE8-dihe-in -139.78, 135.67 APE8-rot-in 306.38 APE67-dihe-in -62.24, -22.22 -42.75, -57.14 APE12-dist-in 7.943 APE11-dist-in 10.793 APE10-dist-in 5.269 APE9-dist-in 3.582 None TPO248 TPO248 XRAY 1.7 0.208 0.243 B 284 278 0 0 0 0 [[93, 343]] 1.0 2vgp Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 3ZTXA Q6DE08 87 356 361.0 ZTX:1357 Type1 Inactive DFGin 5.292 15.355 ABAminus -114.92, -21.17 -133.22, 134.06 -123.23, 32.99 282.31, 84.28 -61.19, -34.71 out-out out 10.451 Saltbr-out 6.493 HRD-in -82.01, -52.17 75.29, 3.59 out-in-in SNCoii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.09, 163.72 APE9-dihe-na 117.29, -143.4 APE8-dihe-in -134.95, 133.3 APE8-rot-in 299.51 APE67-dihe-in -67.73, -15.78 -33.4, -58.65 APE12-dist-in 8.148 APE11-dist-in 10.87 APE10-dist-in 5.199 APE9-dist-in 3.624 None TPO248 TPO248 XRAY 1.95 0.188 0.226 A 284 270 0 0 0 0 [[93, 343]] 1.0 3ztx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 3ZTXB Q6DE08 78 355 361.0 ZTX:1356 Type1 Inactive DFGin 5.668 15.568 ABAminus -113.33, -30.48 -126.05, 115.12 -108.97, 32.49 284.32, 77.45 -65.15, -25.59 out-out out 10.53 Saltbr-out 5.115 HRD-in -80.99, -52.67 76.25, 3.65 out-in-in SNCoii in-in ActLoopNT-in 3.018 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.8, 162.24 APE9-dihe-na 128.32, -146.73 APE8-dihe-in -138.05, 133.93 APE8-rot-in 300.77 APE67-dihe-in -61.78, -24.54 -38.44, -59.14 APE12-dist-in 7.738 APE11-dist-in 10.696 APE10-dist-in 5.187 APE9-dist-in 3.568 None TPO248 TPO248 XRAY 1.95 0.188 0.226 B 284 273 5 0 0 0 [[93, 343]] 1.0 3ztx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8MA Q6DE08 87 357 361.0 VX6:1359 Type1 Inactive DFGin 5.474 15.774 ABAminus -107.28, -33.64 -117.85, 130.37 -121.34, 30.36 281.58, 83.31 -63.32, -28.71 out-out out 10.587 Saltbr-out 6.05 HRD-in -78.01, -57.17 76.89, 5.94 out-in-in SNCoii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.01, 165.76 APE9-dihe-na 112.26, -138.97 APE8-dihe-in -136.32, 135.05 APE8-rot-in 307.84 APE67-dihe-in -64.19, -18.21 -36.05, -60.56 APE12-dist-in 8.192 APE11-dist-in 10.95 APE10-dist-in 5.343 APE9-dist-in 3.517 None TPO248 TPO248 XRAY 1.85 0.193 0.236 A 286 271 0 0 0 0 [[93, 343]] 1.0 4b8m Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8MB Q6DE08 78 357 361.0 VX6:1359 Type1 Inactive DFGin 5.753 15.874 ABAminus -107.1, -42.62 -111.3, 118.7 -113.47, 25.97 282.13, 80.51 -60.76, -22.0 out-out out 10.633 Saltbr-out 5.409 HRD-in -78.11, -51.63 73.89, 2.84 out-in-in SNCoii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.93, 168.47 APE9-dihe-na 121.34, -152.05 APE8-dihe-in -136.52, 138.0 APE8-rot-in 305.16 APE67-dihe-in -64.39, -18.52 -45.42, -55.73 APE12-dist-in 7.957 APE11-dist-in 10.853 APE10-dist-in 5.267 APE9-dist-in 3.484 None TPO248 TPO248 XRAY 1.85 0.193 0.236 B 286 280 0 0 0 0 [[93, 343]] 1.0 4b8m Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 5EYKA Q6DE08 88 355 361.0 5U5:401 Type1.5_Back Inactive DFGin 5.818 16.494 ABAminus -113.53, -11.3 -127.89, 127.9 -123.36, 28.44 280.86, 83.1 -54.75, -34.31 out-out out 11.167 Saltbr-out 6.298 HRD-in -71.81, -53.56 69.94, 2.34 out-in-in SNCoii in-in ActLoopNT-in 2.9 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.24, 164.73 APE9-dihe-na 118.09, -143.76 APE8-dihe-in -130.69, 133.69 APE8-rot-in 302.79 APE67-dihe-in -64.89, -21.02 -31.66, -60.88 APE12-dist-in 8.059 APE11-dist-in 11.155 APE10-dist-in 5.517 APE9-dist-in 3.686 G96V TPO248 TPO248 XRAY 1.93 0.2 0.222 A 276 264 4 0 0 4 [[93, 343]] 1.0 5eyk Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.3e-77 264.5 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VRXB Q6DE08 77 355 361.0 447:1356 Type1.5_Back Inactive DFGin 5.653 15.758 ABAminus -113.46, -27.26 -123.92, 110.09 -106.03, 30.29 284.23, 82.27 -65.09, -18.68 out-out out 10.721 Saltbr-out 5.511 HRD-in -80.07, -54.58 78.53, 0.16 out-in-in SNCoii in-in ActLoopNT-in 2.968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.63, 165.93 APE9-dihe-na 123.43, -149.16 APE8-dihe-in -135.57, 133.36 APE8-rot-in 303.41 APE67-dihe-in -62.94, -19.54 -41.29, -57.33 APE12-dist-in 7.88 APE11-dist-in 10.747 APE10-dist-in 5.203 APE9-dist-in 3.498 None TPO248 TPO248 XRAY 1.86 0.191 0.243 B 285 275 4 0 0 0 [[93, 343]] 1.0 2vrx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 2VRXA Q6DE08 87 355 361.0 447:1356 Type1.5_Front Inactive DFGin 5.42 15.778 ABAminus -105.62, -30.67 -123.67, 131.33 -117.99, 34.15 285.03, 83.66 -62.28, -30.72 out-out out 10.682 Saltbr-out 8.585 HRD-in -81.76, -55.95 77.01, 3.35 out-in-in SNCoii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.89, 162.13 APE9-dihe-na 112.16, -139.2 APE8-dihe-in -134.38, 133.56 APE8-rot-in 313.33 APE67-dihe-in -66.93, -14.33 -36.35, -56.78 APE12-dist-in 8.24 APE11-dist-in 10.984 APE10-dist-in 5.366 APE9-dist-in 3.599 None TPO248 TPO248 XRAY 1.86 0.191 0.243 A 285 269 0 0 0 0 [[93, 343]] 1.0 2vrx Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2VA Q6DE08 87 357 361.0 YJA:1357 Type1.5_Front Inactive DFGin 5.69 15.549 ABAminus -108.16, -35.27 -114.73, 124.49 -117.48, 35.02 287.24, 73.89 -61.26, -33.55 out-out out 10.498 Saltbr-out 6.613 HRD-in -78.14, -58.65 78.38, 3.8 out-in-in SNCoii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.3, 162.85 APE9-dihe-na 114.08, -146.04 APE8-dihe-in -135.51, 133.89 APE8-rot-in 294.11 APE67-dihe-in -71.33, -17.09 -36.81, -55.94 APE12-dist-in 8.288 APE11-dist-in 10.871 APE10-dist-in 5.538 APE9-dist-in 3.614 None TPO248 TPO248 XRAY 1.49 0.168 0.197 A 285 271 0 0 0 0 [[93, 343]] 1.0 4c2v Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4C2VB Q6DE08 76 356 361.0 YJA:1357 Type1.5_Front Inactive DFGin 5.942 15.883 ABAminus -109.55, -42.74 -106.71, 117.87 -113.37, 30.44 284.56, 79.44 -66.62, -22.24 out-out out 10.936 Saltbr-out 5.894 HRD-in -82.35, -52.94 75.14, -4.14 out-in-in SNCoii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.26, 161.88 APE9-dihe-na 127.85, -152.7 APE8-dihe-in -130.87, 132.44 APE8-rot-in 296.15 APE67-dihe-in -67.07, -19.19 -44.45, -53.34 APE12-dist-in 8.111 APE11-dist-in 10.915 APE10-dist-in 5.332 APE9-dist-in 3.644 None TPO248 TPO248 XRAY 1.49 0.168 0.197 B 285 281 0 0 0 0 [[93, 343]] 1.0 4c2v Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.5e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
AUKBA_XENLA 4B8LA Q6DE08 87 351 361.0 A0P:1352 Type1 Inactive DFGin 7.552 15.564 None -81.6, -93.69 -89.24, 141.54 -107.67, 999.0 288.18, 65.55 999.0, 999.0 out-out out 10.561 Saltbr-out 5.944 HRD-in -91.78, -45.75 80.25, -35.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 143.01 APE8-rot-in 294.25 APE67-dihe-in -54.23, -29.34 -30.25, -64.92 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 P353G None None XRAY 3.0 0.24 0.297 A 286 249 16 0 0 16 [[93, 343]] 1.0 4b8l Xenopus laevis CAMK_AURKBA_XENLA CAMK 2.6e-77 265.6 1 256 256 233 234 235 237 239 122 141 145 213 215 214 216 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A