CAMK_AURKB (Aurora kinase B)

Total number of chains: 3
Active chains: 2
Uniprot: AURKB_HUMAN
Kinase Domain Residues: 77 - 327
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-Q96GD4-K1A
DFGinter None 1 33.3% 4AF3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AURKB AF-Q96GD4-K1A Q96GD4 69 335 344.0 No_ligand No_ligand Active DFGin 5.7802 15.0258 BLAminus -127.0, 176.5 57.8, 71.92 -79.61, 19.08 285.14, 75.28 -59.65, -34.69 in-in in 9.4814 Saltbr-in 2.7035 HRD-in -78.88, -50.69 66.99, 11.13 in-in-in SNCiii in-in ActLoopNT-in 3.0049 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.14, 164.25 APE9-dihe-na 101.07, -163.18 APE8-dihe-in -106.28, 136.6 APE8-rot-in 304.12 APE67-dihe-in -69.73, -13.69 -45.42, -54.05 APE12-dist-in 8.5723 APE11-dist-in 11.3886 APE10-dist-in 5.657 APE9-dist-in 3.574 None None None AF2 -1.0 1.0 1.0 A 267.0 267.0 0 26 26 0 [[77, 327]] 1.0 AF-Q96GD4-K1 CAMK_AURKB_HUMAN CAMK 4.2e-80 274.7 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B
AURKB AF-Q96GD4-K3A Q96GD4 69 335 344.0 No_ligand No_ligand Active DFGin 5.5768 14.9916 BLAminus -124.01, 179.54 50.32, 77.12 -79.4, 14.41 288.62, 84.9 -59.82, -34.0 out-in out 10.0784 Saltbr-in 2.759 HRD-in -78.41, -50.15 69.96, -4.31 in-in-in SNCiii in-in ActLoopNT-in 2.9549 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.38, 153.11 APE9-dihe-na 117.94, -172.26 APE8-dihe-in -95.05, 139.82 APE8-rot-in 304.53 APE67-dihe-in -69.06, -14.73 -44.88, -56.87 APE12-dist-in 9.0431 APE11-dist-in 11.5726 APE10-dist-in 5.8355 APE9-dist-in 3.9184 None None None AF2 -1.0 1.0 1.0 A 267.0 267.0 0 26 26 0 [[77, 327]] 1.0 AF-Q96GD4-K3 CAMK_AURKB_HUMAN CAMK 4.2e-80 274.7 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B
AURKB 4AF3A Q96GD4 70 338 344.0 VX6:500 Type1 Inactive DFGinter 6.2261 9.0798 None -112.4, 112.13 -127.45, 99.79 -141.88, 168.72 285.68, 83.55 155.44, 999.0 out-out out 12.1796 Saltbr-out 9.9295 HRD-out -154.61, 151.72 -150.08, 147.62 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -62.83, -29.23 999.0, -55.56 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.75 0.208 0.264 A 292.0 253.0 16 26 10 16 [[77, 327]] 1.0 4af3 CAMK_AURKB_HUMAN CAMK 3.6e-80 274.9 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B

CAMK_AURKB (Aurora kinase B)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-Q96GD4-K1A
DFGinter None 1 33.3% 4AF3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AURKB AURKB_HUMAN AF-Q96GD4-K1A Q96GD4 69 335 344.0 No_ligand No_ligand Active DFGin 5.7802 15.0258 BLAminus -127.0, 176.5 57.8, 71.92 -79.61, 19.08 285.14, 75.28 -59.65, -34.69 in-in in 9.4814 Saltbr-in 2.7035 HRD-in -78.88, -50.69 66.99, 11.13 in-in-in SNCiii in-in ActLoopNT-in 3.0049 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.14, 164.25 APE9-dihe-na 101.07, -163.18 APE8-dihe-in -106.28, 136.6 APE8-rot-in 304.12 APE67-dihe-in -69.73, -13.69 -45.42, -54.05 APE12-dist-in 8.5723 APE11-dist-in 11.3886 APE10-dist-in 5.657 APE9-dist-in 3.574 None None None AF2 -1.0 1.0 1.0 A 267.0 267.0 0 26 26 0 [[77, 327]] 1.0 AF-Q96GD4-K1 Homo sapiens CAMK_AURKB_HUMAN CAMK 4.2e-80 274.7 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B
AURKB AURKB_HUMAN AF-Q96GD4-K3A Q96GD4 69 335 344.0 No_ligand No_ligand Active DFGin 5.5768 14.9916 BLAminus -124.01, 179.54 50.32, 77.12 -79.4, 14.41 288.62, 84.9 -59.82, -34.0 out-in out 10.0784 Saltbr-in 2.759 HRD-in -78.41, -50.15 69.96, -4.31 in-in-in SNCiii in-in ActLoopNT-in 2.9549 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.38, 153.11 APE9-dihe-na 117.94, -172.26 APE8-dihe-in -95.05, 139.82 APE8-rot-in 304.53 APE67-dihe-in -69.06, -14.73 -44.88, -56.87 APE12-dist-in 9.0431 APE11-dist-in 11.5726 APE10-dist-in 5.8355 APE9-dist-in 3.9184 None None None AF2 -1.0 1.0 1.0 A 267.0 267.0 0 26 26 0 [[77, 327]] 1.0 AF-Q96GD4-K3 Homo sapiens CAMK_AURKB_HUMAN CAMK 4.2e-80 274.7 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B
AURKB AURKB_HUMAN 4AF3A Q96GD4 70 338 344.0 VX6:500 Type1 Inactive DFGinter 6.2261 9.0798 None -112.4, 112.13 -127.45, 99.79 -141.88, 168.72 285.68, 83.55 155.44, 999.0 out-out out 12.1796 Saltbr-out 9.9295 HRD-out -154.61, 151.72 -150.08, 147.62 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -62.83, -29.23 999.0, -55.56 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.75 0.208 0.264 A 292.0 253.0 16 26 10 16 [[77, 327]] 1.0 4af3 Homo sapiens CAMK_AURKB_HUMAN CAMK 3.6e-80 274.9 1.0 256.0 256.0 217 218 219 221 223 106 125 129 197 199 198 200.0 255 243 238 237 236 235 234 233 232 155 Aurora kinase B

CAMK_AURKB (Aurora kinase B)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name