| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA6-1 | KS6A6_HUMAN | AF-Q9UK32-K1A | Q9UK32 | 65 | 338 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.7166 | 14.3798 | BLAminus | -122.74, -167.91 | 42.21, 63.67 | -74.28, 13.2 | 286.97, 79.25 | -62.83, -17.84 | in-in | in | 8.9573 | Saltbr-in | 2.6173 | HRD-in | -80.3, -49.99 | 66.24, 7.44 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9045 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.5, 163.94 | APE9-dihe-na | 113.91, 169.75 | APE8-dihe-in | -69.91, 129.74 | APE8-rot-in | 294.78 | APE67-dihe-in | -61.58, -27.56 | -58.44, -40.04 | APE12-dist-in | 8.3195 | APE11-dist-in | 11.3217 | APE10-dist-in | 5.6129 | APE9-dist-in | 3.5642 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K1 | AGC_RPS6KA6-1_HUMAN | AGC | 7.4e-98 | 332.7 | 1.0 | 260.0 | 260.0 | 215 | 216 | 217 | 219 | 221 | 105 | 123 | 127 | 195 | 197 | 196 | 198.0 | 255 | 243 | 238 | 237 | 236 | 235 | 234 | 233 | 232 | 153 | Ribosomal protein S6 kinase alpha-6 |
| AGC | RPS6KA6-1 | KS6A6_HUMAN | AF-Q9UK32-K3A | Q9UK32 | 65 | 338 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.5009 | 14.1016 | BLAminus | -132.27, -175.76 | 52.2, 64.77 | -72.92, 11.15 | 296.44, 84.22 | -64.03, -14.25 | in-in | in | 8.777 | Saltbr-in | 2.623 | HRD-in | -81.65, -46.67 | 67.29, 10.6 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8067 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -156.4, 164.19 | APE9-dihe-na | 112.49, 174.41 | APE8-dihe-in | -75.23, 135.24 | APE8-rot-in | 295.17 | APE67-dihe-in | -61.93, -26.66 | -66.02, -39.52 | APE12-dist-in | 8.4234 | APE11-dist-in | 11.441 | APE10-dist-in | 5.6939 | APE9-dist-in | 3.3677 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K3 | AGC_RPS6KA6-1_HUMAN | AGC | 7.4e-98 | 332.7 | 1.0 | 260.0 | 260.0 | 215 | 216 | 217 | 219 | 221 | 105 | 123 | 127 | 195 | 197 | 196 | 198.0 | 255 | 243 | 238 | 237 | 236 | 235 | 234 | 233 | 232 | 153 | Ribosomal protein S6 kinase alpha-6 |
| CAMK | RPS6KA6-2 | KS6A6_HUMAN | AF-Q9UK32-K2A | Q9UK32 | 418 | 691 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.6941 | 14.1195 | BLAminus | -127.11, -179.69 | 57.75, 68.91 | -77.73, 25.98 | 287.73, 79.4 | -59.46, -33.75 | in-in | in | 8.7959 | Saltbr-in | 2.7406 | HRD-in | -76.48, -42.42 | 69.34, 5.82 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9663 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.57, 125.8 | APE9-dihe-na | -168.54, 160.84 | APE8-dihe-in | -97.66, 131.38 | APE8-rot-in | 298.78 | APE67-dihe-in | -76.51, -14.79 | -51.82, -39.1 | APE12-dist-in | 8.7568 | APE11-dist-in | 10.8685 | APE10-dist-in | 5.0256 | APE9-dist-in | 4.1885 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K2 | CAMK_RPS6KA6-2_HUMAN | CAMK | 3e-86 | 294.8 | 1.0 | 256.0 | 256.0 | 564 | 565 | 566 | 568 | 570 | 455 | 467 | 471 | 540 | 542 | 541 | 543.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 498 | Ribosomal protein S6 kinase alpha-6 |
| CAMK | RPS6KA6-2 | KS6A6_HUMAN | AF-Q9UK32-K4A | Q9UK32 | 418 | 691 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.4341 | 14.2182 | BLAminus | -132.15, -176.4 | 53.04, 63.76 | -70.7, 26.81 | 286.51, 80.64 | -68.87, -29.0 | in-in | in | 8.8545 | Saltbr-in | 2.7163 | HRD-in | -78.09, -41.51 | 66.12, 12.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9057 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.73, 127.94 | APE9-dihe-na | -169.87, 160.84 | APE8-dihe-in | -95.06, 128.48 | APE8-rot-in | 299.27 | APE67-dihe-in | -74.76, -17.34 | -51.97, -39.65 | APE12-dist-in | 8.9319 | APE11-dist-in | 11.0523 | APE10-dist-in | 5.2117 | APE9-dist-in | 4.2897 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K4 | CAMK_RPS6KA6-2_HUMAN | CAMK | 3e-86 | 294.8 | 1.0 | 256.0 | 256.0 | 564 | 565 | 566 | 568 | 570 | 455 | 467 | 471 | 540 | 542 | 541 | 543.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 498 | Ribosomal protein S6 kinase alpha-6 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA6-1 | KS6A6_HUMAN | AF-Q9UK32-K1A | Q9UK32 | 65 | 338 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.7166 | 14.3798 | BLAminus | -122.74, -167.91 | 42.21, 63.67 | -74.28, 13.2 | 286.97, 79.25 | -62.83, -17.84 | in-in | in | 8.9573 | Saltbr-in | 2.6173 | HRD-in | -80.3, -49.99 | 66.24, 7.44 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9045 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.5, 163.94 | APE9-dihe-na | 113.91, 169.75 | APE8-dihe-in | -69.91, 129.74 | APE8-rot-in | 294.78 | APE67-dihe-in | -61.58, -27.56 | -58.44, -40.04 | APE12-dist-in | 8.3195 | APE11-dist-in | 11.3217 | APE10-dist-in | 5.6129 | APE9-dist-in | 3.5642 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K1 | Homo sapiens | AGC_RPS6KA6-1_HUMAN | AGC | 7.4e-98 | 332.7 | 1.0 | 260.0 | 260.0 | 215 | 216 | 217 | 219 | 221 | 105 | 123 | 127 | 195 | 197 | 196 | 198.0 | 255 | 243 | 238 | 237 | 236 | 235 | 234 | 233 | 232 | 153 | Ribosomal protein S6 kinase alpha-6 |
| AGC | RPS6KA6-1 | KS6A6_HUMAN | AF-Q9UK32-K3A | Q9UK32 | 65 | 338 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.5009 | 14.1016 | BLAminus | -132.27, -175.76 | 52.2, 64.77 | -72.92, 11.15 | 296.44, 84.22 | -64.03, -14.25 | in-in | in | 8.777 | Saltbr-in | 2.623 | HRD-in | -81.65, -46.67 | 67.29, 10.6 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8067 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -156.4, 164.19 | APE9-dihe-na | 112.49, 174.41 | APE8-dihe-in | -75.23, 135.24 | APE8-rot-in | 295.17 | APE67-dihe-in | -61.93, -26.66 | -66.02, -39.52 | APE12-dist-in | 8.4234 | APE11-dist-in | 11.441 | APE10-dist-in | 5.6939 | APE9-dist-in | 3.3677 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K3 | Homo sapiens | AGC_RPS6KA6-1_HUMAN | AGC | 7.4e-98 | 332.7 | 1.0 | 260.0 | 260.0 | 215 | 216 | 217 | 219 | 221 | 105 | 123 | 127 | 195 | 197 | 196 | 198.0 | 255 | 243 | 238 | 237 | 236 | 235 | 234 | 233 | 232 | 153 | Ribosomal protein S6 kinase alpha-6 |
| CAMK | RPS6KA6-2 | KS6A6_HUMAN | AF-Q9UK32-K2A | Q9UK32 | 418 | 691 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.6941 | 14.1195 | BLAminus | -127.11, -179.69 | 57.75, 68.91 | -77.73, 25.98 | 287.73, 79.4 | -59.46, -33.75 | in-in | in | 8.7959 | Saltbr-in | 2.7406 | HRD-in | -76.48, -42.42 | 69.34, 5.82 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9663 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.57, 125.8 | APE9-dihe-na | -168.54, 160.84 | APE8-dihe-in | -97.66, 131.38 | APE8-rot-in | 298.78 | APE67-dihe-in | -76.51, -14.79 | -51.82, -39.1 | APE12-dist-in | 8.7568 | APE11-dist-in | 10.8685 | APE10-dist-in | 5.0256 | APE9-dist-in | 4.1885 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K2 | Homo sapiens | CAMK_RPS6KA6-2_HUMAN | CAMK | 3e-86 | 294.8 | 1.0 | 256.0 | 256.0 | 564 | 565 | 566 | 568 | 570 | 455 | 467 | 471 | 540 | 542 | 541 | 543.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 498 | Ribosomal protein S6 kinase alpha-6 |
| CAMK | RPS6KA6-2 | KS6A6_HUMAN | AF-Q9UK32-K4A | Q9UK32 | 418 | 691 | 745.0 | No_ligand | No_ligand | Active | DFGin | 6.4341 | 14.2182 | BLAminus | -132.15, -176.4 | 53.04, 63.76 | -70.7, 26.81 | 286.51, 80.64 | -68.87, -29.0 | in-in | in | 8.8545 | Saltbr-in | 2.7163 | HRD-in | -78.09, -41.51 | 66.12, 12.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9057 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.73, 127.94 | APE9-dihe-na | -169.87, 160.84 | APE8-dihe-in | -95.06, 128.48 | APE8-rot-in | 299.27 | APE67-dihe-in | -74.76, -17.34 | -51.97, -39.65 | APE12-dist-in | 8.9319 | APE11-dist-in | 11.0523 | APE10-dist-in | 5.2117 | APE9-dist-in | 4.2897 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[73, 330], [426, 683]] | 2.0 | AF-Q9UK32-K4 | Homo sapiens | CAMK_RPS6KA6-2_HUMAN | CAMK | 3e-86 | 294.8 | 1.0 | 256.0 | 256.0 | 564 | 565 | 566 | 568 | 570 | 455 | 467 | 471 | 540 | 542 | 541 | 543.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 498 | Ribosomal protein S6 kinase alpha-6 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|