PDB: AF-Q9NR20 — CMGC DYRK4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9NR20-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK4 DYRK4_HUMAN AF-Q9NR20-K1A Q9NR20 96 408 520.0 No_ligand No_ligand Active DFGin 6.9399 14.7187 BLAminus -124.04, 176.92 62.19, 60.84 -76.47, 12.95 286.25, 81.3 -65.81, -22.66 in-in in 8.7426 Saltbr-in 2.749 HRD-in -66.75, -37.24 66.29, -14.43 in-in-in SNCiii in-in ActLoopNT-in 2.8239 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.79, 176.9 APE9-dihe-na 61.61, 143.32 APE8-dihe-in -64.88, 138.72 APE8-rot-in 293.68 APE67-dihe-in -65.78, -20.92 -53.04, -44.67 APE12-dist-in 12.9306 APE11-dist-in 11.4079 APE10-dist-in 7.2645 APE9-dist-in 3.0305 None None None AF2 -1.0 1.0 1.0 A 313.0 313.0 0 25 25 0 [[104, 400]] 1.0 AF-Q9NR20-K1 CMGC_DYRK4_HUMAN CMGC 8e-98 333.2 1.0 301.0 301.0 249 250 251 253 255 133 148 152 227 229 228 230.0 286 274 269 268 267 266 265 264 263 184 Dual specificity tyrosine-phosphorylation-regulated kinase 4
CMGC DYRK4 DYRK4_HUMAN AF-Q9NR20-K3A Q9NR20 96 408 520.0 No_ligand No_ligand Active DFGin 6.6454 14.3931 BLAminus -128.08, 176.16 62.53, 62.73 -76.63, 11.35 291.68, 83.66 -67.07, -18.07 in-in in 8.8031 Saltbr-in 2.7326 HRD-in -68.69, -38.02 65.51, -5.47 in-in-in SNCiii in-in ActLoopNT-in 2.8666 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.76, 178.86 APE9-dihe-na 61.23, 142.54 APE8-dihe-in -63.68, 135.59 APE8-rot-in 291.4 APE67-dihe-in -64.98, -23.25 -55.11, -44.48 APE12-dist-in 12.9307 APE11-dist-in 11.4771 APE10-dist-in 7.1396 APE9-dist-in 3.1073 None None None AF2 -1.0 1.0 1.0 A 313.0 313.0 0 25 25 0 [[104, 400]] 1.0 AF-Q9NR20-K3 CMGC_DYRK4_HUMAN CMGC 8e-98 333.2 1.0 301.0 301.0 249 250 251 253 255 133 148 152 227 229 228 230.0 286 274 269 268 267 266 265 264 263 184 Dual specificity tyrosine-phosphorylation-regulated kinase 4

PDB: AF-Q9NR20 — CMGC DYRK4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9NR20-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK4 DYRK4_HUMAN AF-Q9NR20-K1A Q9NR20 96 408 520.0 No_ligand No_ligand Active DFGin 6.9399 14.7187 BLAminus -124.04, 176.92 62.19, 60.84 -76.47, 12.95 286.25, 81.3 -65.81, -22.66 in-in in 8.7426 Saltbr-in 2.749 HRD-in -66.75, -37.24 66.29, -14.43 in-in-in SNCiii in-in ActLoopNT-in 2.8239 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.79, 176.9 APE9-dihe-na 61.61, 143.32 APE8-dihe-in -64.88, 138.72 APE8-rot-in 293.68 APE67-dihe-in -65.78, -20.92 -53.04, -44.67 APE12-dist-in 12.9306 APE11-dist-in 11.4079 APE10-dist-in 7.2645 APE9-dist-in 3.0305 None None None AF2 -1.0 1.0 1.0 A 313.0 313.0 0 25 25 0 [[104, 400]] 1.0 AF-Q9NR20-K1 Homo sapiens CMGC_DYRK4_HUMAN CMGC 8e-98 333.2 1.0 301.0 301.0 249 250 251 253 255 133 148 152 227 229 228 230.0 286 274 269 268 267 266 265 264 263 184 Dual specificity tyrosine-phosphorylation-regulated kinase 4
CMGC DYRK4 DYRK4_HUMAN AF-Q9NR20-K3A Q9NR20 96 408 520.0 No_ligand No_ligand Active DFGin 6.6454 14.3931 BLAminus -128.08, 176.16 62.53, 62.73 -76.63, 11.35 291.68, 83.66 -67.07, -18.07 in-in in 8.8031 Saltbr-in 2.7326 HRD-in -68.69, -38.02 65.51, -5.47 in-in-in SNCiii in-in ActLoopNT-in 2.8666 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.76, 178.86 APE9-dihe-na 61.23, 142.54 APE8-dihe-in -63.68, 135.59 APE8-rot-in 291.4 APE67-dihe-in -64.98, -23.25 -55.11, -44.48 APE12-dist-in 12.9307 APE11-dist-in 11.4771 APE10-dist-in 7.1396 APE9-dist-in 3.1073 None None None AF2 -1.0 1.0 1.0 A 313.0 313.0 0 25 25 0 [[104, 400]] 1.0 AF-Q9NR20-K3 Homo sapiens CMGC_DYRK4_HUMAN CMGC 8e-98 333.2 1.0 301.0 301.0 249 250 251 253 255 133 148 152 227 229 228 230.0 286 274 269 268 267 266 265 264 263 184 Dual specificity tyrosine-phosphorylation-regulated kinase 4

PDB: AF-Q9NR20 — CMGC DYRK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name