CMGC_DYRK4 (Dual specificity tyrosine-phosphorylation-regulated kinase 4)

Total number of chains: 2
Active chains: 2
Uniprot: DYRK4_HUMAN
Kinase Domain Residues: 104 - 400
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9NR20-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9NR20-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 96 - 408 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 4
AF-Q9NR20-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 96 - 408 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 4

CMGC_DYRK4 (Dual specificity tyrosine-phosphorylation-regulated kinase 4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9NR20-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DYRK4_HUMAN AF-Q9NR20-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 96 - 408 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 4 Homo sapiens
DYRK4_HUMAN AF-Q9NR20-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 96 - 408 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 4 Homo sapiens

CMGC_DYRK4 (Dual specificity tyrosine-phosphorylation-regulated kinase 4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism