PDB: AF-Q5S007 — TKL LRRK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q5S007-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K1A Q5S007 1867 2142 2527.0 No_ligand No_ligand Active DFGin 6.2289 13.0184 BLAminus -123.42, -177.15 48.16, 92.04 -100.88, 18.77 306.82, 91.94 -55.24, -29.66 in-in in 8.5226 Saltbr-in 2.7409 HRD-in -79.01, -43.93 67.99, -8.85 in-in-in SNCiii in-in ActLoopNT-in 2.8557 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.22, 143.85 APE9-dihe-na 143.4, 155.54 APE8-dihe-in -77.65, 123.56 APE8-rot-in 291.78 APE67-dihe-inflip 80.21, 1.47 -53.68, 143.02 APE12-dist-in 9.0778 APE11-dist-in 11.7091 APE10-dist-in 5.6489 APE9-dist-in 3.3733 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[1875, 2134]] 1.0 AF-Q5S007-K1 TKL_LRRK2_HUMAN TKL 3.4e-59 206.4 5.0 266.0 262.0 2016 2017 2018 2020 2022 1906 1920 1924 1991 1993 1992 1994.0 2055 2042 2037 2036 2035 2034 2033 2032 2031 1948 Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K3A Q5S007 1867 2142 2527.0 No_ligand No_ligand Active DFGin 6.328 13.3987 BLAminus -133.98, -172.94 51.72, 69.61 -85.29, 16.73 308.68, 103.46 -56.98, -31.93 in-in in 8.3926 Saltbr-in 2.7668 HRD-in -86.23, -45.15 69.51, -3.36 in-in-in SNCiii in-in ActLoopNT-in 2.8818 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.61, 122.15 APE9-dihe-na 162.76, 154.5 APE8-dihe-in -73.2, 129.38 APE8-rot-in 298.65 APE67-dihe-inflip 69.21, 15.98 -53.32, 138.33 APE12-dist-in 9.2299 APE11-dist-in 11.9129 APE10-dist-in 5.9109 APE9-dist-in 3.4313 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[1875, 2134]] 1.0 AF-Q5S007-K3 TKL_LRRK2_HUMAN TKL 3.4e-59 206.4 5.0 266.0 262.0 2016 2017 2018 2020 2022 1906 1920 1924 1991 1993 1992 1994.0 2055 2042 2037 2036 2035 2034 2033 2032 2031 1948 Leucine-rich repeat serine/threonine-protein kinase 2

PDB: AF-Q5S007 — TKL LRRK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q5S007-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K1A Q5S007 1867 2142 2527.0 No_ligand No_ligand Active DFGin 6.2289 13.0184 BLAminus -123.42, -177.15 48.16, 92.04 -100.88, 18.77 306.82, 91.94 -55.24, -29.66 in-in in 8.5226 Saltbr-in 2.7409 HRD-in -79.01, -43.93 67.99, -8.85 in-in-in SNCiii in-in ActLoopNT-in 2.8557 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.22, 143.85 APE9-dihe-na 143.4, 155.54 APE8-dihe-in -77.65, 123.56 APE8-rot-in 291.78 APE67-dihe-inflip 80.21, 1.47 -53.68, 143.02 APE12-dist-in 9.0778 APE11-dist-in 11.7091 APE10-dist-in 5.6489 APE9-dist-in 3.3733 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[1875, 2134]] 1.0 AF-Q5S007-K1 Homo sapiens TKL_LRRK2_HUMAN TKL 3.4e-59 206.4 5.0 266.0 262.0 2016 2017 2018 2020 2022 1906 1920 1924 1991 1993 1992 1994.0 2055 2042 2037 2036 2035 2034 2033 2032 2031 1948 Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K3A Q5S007 1867 2142 2527.0 No_ligand No_ligand Active DFGin 6.328 13.3987 BLAminus -133.98, -172.94 51.72, 69.61 -85.29, 16.73 308.68, 103.46 -56.98, -31.93 in-in in 8.3926 Saltbr-in 2.7668 HRD-in -86.23, -45.15 69.51, -3.36 in-in-in SNCiii in-in ActLoopNT-in 2.8818 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.61, 122.15 APE9-dihe-na 162.76, 154.5 APE8-dihe-in -73.2, 129.38 APE8-rot-in 298.65 APE67-dihe-inflip 69.21, 15.98 -53.32, 138.33 APE12-dist-in 9.2299 APE11-dist-in 11.9129 APE10-dist-in 5.9109 APE9-dist-in 3.4313 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[1875, 2134]] 1.0 AF-Q5S007-K3 Homo sapiens TKL_LRRK2_HUMAN TKL 3.4e-59 206.4 5.0 266.0 262.0 2016 2017 2018 2020 2022 1906 1920 1924 1991 1993 1992 1994.0 2055 2042 2037 2036 2035 2034 2033 2032 2031 1948 Leucine-rich repeat serine/threonine-protein kinase 2

PDB: AF-Q5S007 — TKL LRRK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name