| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA1-1 | KS6A1_HUMAN | AF-Q15418-K1A | Q15418 | 54 | 329 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.6211 | 14.3552 | BLAminus | -124.04, -166.26 | 40.15, 63.05 | -75.14, 13.01 | 287.46, 77.73 | -62.04, -17.57 | in-in | in | 8.9956 | Saltbr-in | 2.6553 | HRD-in | -82.17, -49.64 | 65.88, 6.04 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9042 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -158.23, 164.1 | APE9-dihe-na | 113.31, 168.76 | APE8-dihe-in | -68.46, 130.82 | APE8-rot-in | 292.77 | APE67-dihe-in | -60.62, -26.43 | -61.01, -40.77 | APE12-dist-in | 8.4157 | APE11-dist-in | 11.4063 | APE10-dist-in | 5.6955 | APE9-dist-in | 3.4929 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K1 | AGC_RPS6KA1-1_HUMAN | AGC | 8.9e-96 | 325.9 | 1.0 | 260.0 | 260.0 | 204 | 205 | 206 | 208 | 210 | 94 | 112 | 116 | 184 | 186 | 185 | 187.0 | 244 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 142 | Ribosomal protein S6 kinase alpha-1 |
| AGC | RPS6KA1-1 | KS6A1_HUMAN | AF-Q15418-K3A | Q15418 | 54 | 329 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.4457 | 14.3519 | BLAminus | -131.09, -177.74 | 50.28, 63.61 | -71.56, 10.34 | 294.57, 83.15 | -62.78, -13.6 | in-in | in | 8.88 | Saltbr-in | 2.6627 | HRD-in | -82.73, -46.46 | 67.14, 11.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8525 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.19, 164.66 | APE9-dihe-na | 112.66, 172.32 | APE8-dihe-in | -74.19, 134.18 | APE8-rot-in | 293.08 | APE67-dihe-in | -61.38, -26.34 | -64.42, -40.72 | APE12-dist-in | 8.366 | APE11-dist-in | 11.4324 | APE10-dist-in | 5.6764 | APE9-dist-in | 3.3874 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K3 | AGC_RPS6KA1-1_HUMAN | AGC | 8.9e-96 | 325.9 | 1.0 | 260.0 | 260.0 | 204 | 205 | 206 | 208 | 210 | 94 | 112 | 116 | 184 | 186 | 185 | 187.0 | 244 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 142 | Ribosomal protein S6 kinase alpha-1 |
| CAMK | RPS6KA1-2 | KS6A1_HUMAN | AF-Q15418-K2A | Q15418 | 410 | 683 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.6419 | 14.0899 | BLAminus | -126.21, 179.26 | 57.08, 67.05 | -75.1, 22.9 | 287.48, 76.88 | -58.82, -29.2 | in-in | in | 8.8915 | Saltbr-in | 2.7387 | HRD-in | -76.33, -42.0 | 69.77, -2.48 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9656 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -133.48, 128.95 | APE9-dihe-na | -170.39, 159.86 | APE8-dihe-in | -93.38, 131.54 | APE8-rot-in | 299.75 | APE67-dihe-in | -74.29, -9.58 | -51.89, -40.62 | APE12-dist-in | 8.8813 | APE11-dist-in | 10.7555 | APE10-dist-in | 4.9201 | APE9-dist-in | 4.0814 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K2 | CAMK_RPS6KA1-2_HUMAN | CAMK | 6.5e-88 | 300.3 | 1.0 | 256.0 | 256.0 | 556 | 557 | 558 | 560 | 562 | 447 | 459 | 463 | 532 | 534 | 533 | 535.0 | 596 | 584 | 579 | 578 | 577 | 576 | 575 | 574 | 573 | 490 | Ribosomal protein S6 kinase alpha-1 |
| CAMK | RPS6KA1-2 | KS6A1_HUMAN | AF-Q15418-K4A | Q15418 | 410 | 683 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.4569 | 14.2616 | BLAminus | -131.98, -176.82 | 54.0, 62.76 | -70.03, 23.23 | 286.1, 80.23 | -67.75, -25.43 | in-in | in | 8.9278 | Saltbr-in | 2.7183 | HRD-in | -78.48, -40.45 | 68.79, 2.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9067 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.11, 131.7 | APE9-dihe-na | -172.39, 156.57 | APE8-dihe-in | -86.39, 129.69 | APE8-rot-in | 298.28 | APE67-dihe-in | -79.01, -8.51 | -53.84, -37.0 | APE12-dist-in | 8.9196 | APE11-dist-in | 10.9642 | APE10-dist-in | 5.0835 | APE9-dist-in | 4.0332 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K4 | CAMK_RPS6KA1-2_HUMAN | CAMK | 6.5e-88 | 300.3 | 1.0 | 256.0 | 256.0 | 556 | 557 | 558 | 560 | 562 | 447 | 459 | 463 | 532 | 534 | 533 | 535.0 | 596 | 584 | 579 | 578 | 577 | 576 | 575 | 574 | 573 | 490 | Ribosomal protein S6 kinase alpha-1 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA1-1 | KS6A1_HUMAN | AF-Q15418-K1A | Q15418 | 54 | 329 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.6211 | 14.3552 | BLAminus | -124.04, -166.26 | 40.15, 63.05 | -75.14, 13.01 | 287.46, 77.73 | -62.04, -17.57 | in-in | in | 8.9956 | Saltbr-in | 2.6553 | HRD-in | -82.17, -49.64 | 65.88, 6.04 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9042 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -158.23, 164.1 | APE9-dihe-na | 113.31, 168.76 | APE8-dihe-in | -68.46, 130.82 | APE8-rot-in | 292.77 | APE67-dihe-in | -60.62, -26.43 | -61.01, -40.77 | APE12-dist-in | 8.4157 | APE11-dist-in | 11.4063 | APE10-dist-in | 5.6955 | APE9-dist-in | 3.4929 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K1 | Homo sapiens | AGC_RPS6KA1-1_HUMAN | AGC | 8.9e-96 | 325.9 | 1.0 | 260.0 | 260.0 | 204 | 205 | 206 | 208 | 210 | 94 | 112 | 116 | 184 | 186 | 185 | 187.0 | 244 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 142 | Ribosomal protein S6 kinase alpha-1 |
| AGC | RPS6KA1-1 | KS6A1_HUMAN | AF-Q15418-K3A | Q15418 | 54 | 329 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.4457 | 14.3519 | BLAminus | -131.09, -177.74 | 50.28, 63.61 | -71.56, 10.34 | 294.57, 83.15 | -62.78, -13.6 | in-in | in | 8.88 | Saltbr-in | 2.6627 | HRD-in | -82.73, -46.46 | 67.14, 11.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8525 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.19, 164.66 | APE9-dihe-na | 112.66, 172.32 | APE8-dihe-in | -74.19, 134.18 | APE8-rot-in | 293.08 | APE67-dihe-in | -61.38, -26.34 | -64.42, -40.72 | APE12-dist-in | 8.366 | APE11-dist-in | 11.4324 | APE10-dist-in | 5.6764 | APE9-dist-in | 3.3874 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K3 | Homo sapiens | AGC_RPS6KA1-1_HUMAN | AGC | 8.9e-96 | 325.9 | 1.0 | 260.0 | 260.0 | 204 | 205 | 206 | 208 | 210 | 94 | 112 | 116 | 184 | 186 | 185 | 187.0 | 244 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 142 | Ribosomal protein S6 kinase alpha-1 |
| CAMK | RPS6KA1-2 | KS6A1_HUMAN | AF-Q15418-K2A | Q15418 | 410 | 683 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.6419 | 14.0899 | BLAminus | -126.21, 179.26 | 57.08, 67.05 | -75.1, 22.9 | 287.48, 76.88 | -58.82, -29.2 | in-in | in | 8.8915 | Saltbr-in | 2.7387 | HRD-in | -76.33, -42.0 | 69.77, -2.48 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9656 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -133.48, 128.95 | APE9-dihe-na | -170.39, 159.86 | APE8-dihe-in | -93.38, 131.54 | APE8-rot-in | 299.75 | APE67-dihe-in | -74.29, -9.58 | -51.89, -40.62 | APE12-dist-in | 8.8813 | APE11-dist-in | 10.7555 | APE10-dist-in | 4.9201 | APE9-dist-in | 4.0814 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K2 | Homo sapiens | CAMK_RPS6KA1-2_HUMAN | CAMK | 6.5e-88 | 300.3 | 1.0 | 256.0 | 256.0 | 556 | 557 | 558 | 560 | 562 | 447 | 459 | 463 | 532 | 534 | 533 | 535.0 | 596 | 584 | 579 | 578 | 577 | 576 | 575 | 574 | 573 | 490 | Ribosomal protein S6 kinase alpha-1 |
| CAMK | RPS6KA1-2 | KS6A1_HUMAN | AF-Q15418-K4A | Q15418 | 410 | 683 | 735.0 | No_ligand | No_ligand | Active | DFGin | 6.4569 | 14.2616 | BLAminus | -131.98, -176.82 | 54.0, 62.76 | -70.03, 23.23 | 286.1, 80.23 | -67.75, -25.43 | in-in | in | 8.9278 | Saltbr-in | 2.7183 | HRD-in | -78.48, -40.45 | 68.79, 2.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9067 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.11, 131.7 | APE9-dihe-na | -172.39, 156.57 | APE8-dihe-in | -86.39, 129.69 | APE8-rot-in | 298.28 | APE67-dihe-in | -79.01, -8.51 | -53.84, -37.0 | APE12-dist-in | 8.9196 | APE11-dist-in | 10.9642 | APE10-dist-in | 5.0835 | APE9-dist-in | 4.0332 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[62, 321], [418, 675]] | 2.0 | AF-Q15418-K4 | Homo sapiens | CAMK_RPS6KA1-2_HUMAN | CAMK | 6.5e-88 | 300.3 | 1.0 | 256.0 | 256.0 | 556 | 557 | 558 | 560 | 562 | 447 | 459 | 463 | 532 | 534 | 533 | 535.0 | 596 | 584 | 579 | 578 | 577 | 576 | 575 | 574 | 573 | 490 | Ribosomal protein S6 kinase alpha-1 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|