PDB: AF-Q12851 — STE M4K2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12851-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K2 M4K2_HUMAN AF-Q12851-K1A Q12851 8 281 820.0 No_ligand No_ligand Active DFGin 6.1912 13.9464 BLAminus -138.05, 174.91 58.29, 70.79 -86.07, 14.92 295.55, 92.97 -57.87, -30.92 in-in in 8.5773 Saltbr-in 2.7344 HRD-in -84.26, -44.15 65.18, 3.54 in-in-in SNCiii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.15, 155.36 APE9-dihe-na 117.59, 174.48 APE8-dihe-in -80.93, 131.1 APE8-rot-in 306.92 APE67-dihe-inflip 75.82, -38.49 -49.77, 157.09 APE12-dist-in 8.8041 APE11-dist-in 11.7186 APE10-dist-in 5.9306 APE9-dist-in 3.4785 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[16, 273]] 1.0 AF-Q12851-K1 STE_MAP4K2_HUMAN STE 8.1e-95 322.9 1.0 256.0 256.0 153 154 155 157 159 45 61 65 133 135 134 136.0 196 181 176 175 174 173 172 171 170 91 Mitogen-activated protein kinase kinase kinase kinase 2
STE MAP4K2 M4K2_HUMAN AF-Q12851-K3A Q12851 8 281 820.0 No_ligand No_ligand Active DFGin 6.0601 14.0448 BLAminus -141.28, 170.24 56.56, 73.6 -81.97, 11.07 290.7, 86.48 -56.84, -29.39 in-in in 8.7416 Saltbr-in 2.7623 HRD-in -78.88, -43.85 67.61, 2.77 in-in-in SNCiii in-in ActLoopNT-in 2.7951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.39, 150.84 APE9-dihe-na 125.98, 170.33 APE8-dihe-in -79.49, 123.85 APE8-rot-in 303.97 APE67-dihe-in -73.52, -24.38 -44.89, -45.28 APE12-dist-in 8.9698 APE11-dist-in 11.6469 APE10-dist-in 5.9158 APE9-dist-in 3.258 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[16, 273]] 1.0 AF-Q12851-K3 STE_MAP4K2_HUMAN STE 8.1e-95 322.9 1.0 256.0 256.0 153 154 155 157 159 45 61 65 133 135 134 136.0 196 181 176 175 174 173 172 171 170 91 Mitogen-activated protein kinase kinase kinase kinase 2

PDB: AF-Q12851 — STE M4K2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12851-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K2 M4K2_HUMAN AF-Q12851-K1A Q12851 8 281 820.0 No_ligand No_ligand Active DFGin 6.1912 13.9464 BLAminus -138.05, 174.91 58.29, 70.79 -86.07, 14.92 295.55, 92.97 -57.87, -30.92 in-in in 8.5773 Saltbr-in 2.7344 HRD-in -84.26, -44.15 65.18, 3.54 in-in-in SNCiii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.15, 155.36 APE9-dihe-na 117.59, 174.48 APE8-dihe-in -80.93, 131.1 APE8-rot-in 306.92 APE67-dihe-inflip 75.82, -38.49 -49.77, 157.09 APE12-dist-in 8.8041 APE11-dist-in 11.7186 APE10-dist-in 5.9306 APE9-dist-in 3.4785 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[16, 273]] 1.0 AF-Q12851-K1 Homo sapiens STE_MAP4K2_HUMAN STE 8.1e-95 322.9 1.0 256.0 256.0 153 154 155 157 159 45 61 65 133 135 134 136.0 196 181 176 175 174 173 172 171 170 91 Mitogen-activated protein kinase kinase kinase kinase 2
STE MAP4K2 M4K2_HUMAN AF-Q12851-K3A Q12851 8 281 820.0 No_ligand No_ligand Active DFGin 6.0601 14.0448 BLAminus -141.28, 170.24 56.56, 73.6 -81.97, 11.07 290.7, 86.48 -56.84, -29.39 in-in in 8.7416 Saltbr-in 2.7623 HRD-in -78.88, -43.85 67.61, 2.77 in-in-in SNCiii in-in ActLoopNT-in 2.7951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.39, 150.84 APE9-dihe-na 125.98, 170.33 APE8-dihe-in -79.49, 123.85 APE8-rot-in 303.97 APE67-dihe-in -73.52, -24.38 -44.89, -45.28 APE12-dist-in 8.9698 APE11-dist-in 11.6469 APE10-dist-in 5.9158 APE9-dist-in 3.258 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[16, 273]] 1.0 AF-Q12851-K3 Homo sapiens STE_MAP4K2_HUMAN STE 8.1e-95 322.9 1.0 256.0 256.0 153 154 155 157 159 45 61 65 133 135 134 136.0 196 181 176 175 174 173 172 171 170 91 Mitogen-activated protein kinase kinase kinase kinase 2

PDB: AF-Q12851 — STE M4K2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name