PDB: AF-P52564 — STE MP2K6_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P52564-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN AF-P52564-K1A P52564 45 322 334.0 No_ligand No_ligand Active DFGin 5.9048 13.4996 BLAminus -145.69, 178.96 61.44, 66.89 -85.87, 11.44 309.77, 111.48 -67.09, -18.76 in-na in 7.589 Saltbr-na 2.667 HRD-in -74.85, -45.86 69.56, -2.68 na-in-in SNCaii in-in ActLoopNT-in 2.8851 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -76.95, 150.78 APE9-dihe-na 93.16, 167.58 APE8-dihe-in -77.2, 117.73 APE8-rot-na 197.0 APE67-dihe-in -66.97, -22.1 -48.05, -44.63 APE12-dist-in 12.7751 APE11-dist-in 10.3843 APE10-dist-in 5.3987 APE9-dist-in 3.4485 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 27 27 0 [[53, 314]] 1.0 AF-P52564-K1 STE_MAP2K6_HUMAN STE 2.3e-85 292.0 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN AF-P52564-K3A P52564 45 322 334.0 No_ligand No_ligand Active DFGin 5.626 13.5004 BLAminus -148.45, -176.54 62.42, 65.82 -84.37, 5.85 308.37, 109.48 -62.57, -20.53 in-na in 8.1127 Saltbr-na 2.697 HRD-in -76.25, -41.87 69.23, -6.15 na-in-in SNCaii in-in ActLoopNT-in 2.8793 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -123.41, 140.98 APE9-dihe-na 110.2, 162.45 APE8-dihe-in -76.59, 111.53 APE8-rot-na 194.17 APE67-dihe-in -66.13, -23.13 -42.41, -45.83 APE12-dist-in 12.7696 APE11-dist-in 10.7611 APE10-dist-in 5.4497 APE9-dist-in 3.444 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 27 27 0 [[53, 314]] 1.0 AF-P52564-K3 STE_MAP2K6_HUMAN STE 2.3e-85 292.0 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: AF-P52564 — STE MP2K6_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P52564-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN AF-P52564-K1A P52564 45 322 334.0 No_ligand No_ligand Active DFGin 5.9048 13.4996 BLAminus -145.69, 178.96 61.44, 66.89 -85.87, 11.44 309.77, 111.48 -67.09, -18.76 in-na in 7.589 Saltbr-na 2.667 HRD-in -74.85, -45.86 69.56, -2.68 na-in-in SNCaii in-in ActLoopNT-in 2.8851 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -76.95, 150.78 APE9-dihe-na 93.16, 167.58 APE8-dihe-in -77.2, 117.73 APE8-rot-na 197.0 APE67-dihe-in -66.97, -22.1 -48.05, -44.63 APE12-dist-in 12.7751 APE11-dist-in 10.3843 APE10-dist-in 5.3987 APE9-dist-in 3.4485 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 27 27 0 [[53, 314]] 1.0 AF-P52564-K1 Homo sapiens STE_MAP2K6_HUMAN STE 2.3e-85 292.0 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN AF-P52564-K3A P52564 45 322 334.0 No_ligand No_ligand Active DFGin 5.626 13.5004 BLAminus -148.45, -176.54 62.42, 65.82 -84.37, 5.85 308.37, 109.48 -62.57, -20.53 in-na in 8.1127 Saltbr-na 2.697 HRD-in -76.25, -41.87 69.23, -6.15 na-in-in SNCaii in-in ActLoopNT-in 2.8793 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -123.41, 140.98 APE9-dihe-na 110.2, 162.45 APE8-dihe-in -76.59, 111.53 APE8-rot-na 194.17 APE67-dihe-in -66.13, -23.13 -42.41, -45.83 APE12-dist-in 12.7696 APE11-dist-in 10.7611 APE10-dist-in 5.4497 APE9-dist-in 3.444 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 27 27 0 [[53, 314]] 1.0 AF-P52564-K3 Homo sapiens STE_MAP2K6_HUMAN STE 2.3e-85 292.0 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: AF-P52564 — STE MP2K6_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name